Pralidoxime Chloride (2-Pam) & Proparacaine Ophthalmic Solution PDF

GENERIC NAME pralidoxime chloride (2-Pam) TRADE, BRAND, OR PROPRIETARY NAME • Protopam® CLASS • Antidote STANDARD SUPPLY • Auto-injector MECHANISM OF ACTION • Regenerates cholinesterase activity that became inhibited by an organophosphate pesticide INDICATION • Organophosphate pesticide poisoning C...

GENERIC NAME pralidoxime chloride (2-Pam) TRADE, BRAND, OR PROPRIETARY NAME • Protopam® CLASS • Antidote STANDARD SUPPLY • Auto-injector MECHANISM OF ACTION • Regenerates cholinesterase activity that became inhibited by an organophosphate pesticide INDICATION • Organophosphate pesticide poisoning CONTRAINDICATIONS • None in the emergency setting • Not recommended for use with pediatric patients ADVERSE REACTIONS/SIDE EFFECTS • Tachycardia • Hypertension • Dizziness • Headache • Blurred vision ROUTE OF ADMINISTRATION • IM ONSET OF ACTION • Variable ADULT DOSAGES • Auto-injector: 600 mg • May repeat the dosage after 15 minutes SPECIAL CONSIDERATIONS • The drug may be used in conjunction with atropine sulfate • The peak effect of the drug is 10 to 20 minutes • The duration of the drug is variable PRALIDOXIME CHLORIDE (2-PAM) 1 GENERIC NAME proparacaine ophthalmic solution 0.5% TRADE, BRAND, OR PROPRIETARY NAME • Alcaine® CLASS • Topical anesthetic STANDARD SUPPLY • Eye drop bottle MECHANISM OF ACTION • Alleviates pain at the ophthalmic nerve cell membrane INDICATION • Chemical exposure to the eyes requiring irrigation CONTRAINDICATION • Known hypersensitivity to the drug ADVERSE REACTIONS/SIDE EFFECTS • Stinging • Burning • Irritation • Conjunctival redness ROUTE OF ADMINISTRATION • Ocular ONSET OF ACTION • 30 seconds to 2 minutes ADULT DOSAGES • 1 to 2 drops PEDIATRIC DOSAGES • 1 to 2 drops SPECIAL CONSIDERATIONS • The peak effect of the drug is 30 seconds to 2 minutes • The duration of the drug is 5 to 10 minutes PROPARACAINE OPHTHALMIC SOLUTION 0.5% 1