Pharmacology Key Terms PDF
Document Details

Uploaded by WarmHeliotrope5861
Tags
Summary
This document provides a glossary of key terms in pharmacology. It defines concepts such as absorption, adverse effects, and drug interactions, aiming to establish a foundational understanding of how drugs interact with the body and other medications. The resource is beneficial for anyone studying pharmacology.
Full Transcript
Pharmacology Key Terms Key Terms The first stage of pharmacokinetics: medications enter the absorption body and travel from the...
Pharmacology Key Terms Key Terms The first stage of pharmacokinetics: medications enter the absorption body and travel from the site of administration into the body's circulation. An unintended pharmacological effect adverse effects that occurs when a medication is administered correctly. The strength of binding affinity between drug and receptor. A drug which binds to its agonist "receptor" and produces its characteristic effect. A molecule that prevents the action of other molecules, often by antagonist competing for a cellular receptor; opposite of agonist. The ability of a drug or other chemical to be taken up by the body bioavailability and made available in the tissue where it is needed. blood-brain barrier A nearly impenetrable barricade that is built from a tightly woven Pharmacology Key Terms 1 mesh of capillaries cemented together to protect the brain from potentially dangerous substances such as poisons or viruses. Individual consumer of healthcare services who clients can be either a patient, resident or tenant The second stage of pharmacokinetics; the distribution process by which medication is distributed throughout the body. As the dose of a drug increases, the response should increase. The dose-response slope of the curve is characteristic of the particular drug-receptor interaction. Medications or other substances that have a drugs physiological effect when introduced to the body. The length of time that a medication is available duration within the body and producing its desired therapeutic effect. The maximum effect of efficacy which the drug is capable. excretion The final stage of pharmacokinetics; process by which the Pharmacology Key Terms 2 body eliminates waste or excess. The breakdown of orally first-pass effect administered drugs in the liver and intestines. The rate at which 50% half-life of a drug is eliminated from the bloodstream. How a medication works mechanism of action at a cellular level within the body. The breakdown of a drug molecule via enzymes in metabolism the liver (primarily) or intestines (secondarily). When a medication first begins to work and onset exerts a therapeutic effect. When the maximum peak concentration of drug is in the body. The study of how drugs pharmacodynamics act at target sites of action in the body. The study of how people's genes affect pharmacogenetics their response to medicines. The study of how the body absorbs, pharmacokinetics distributes, metabolizes, and eliminates drugs. The science dealing with pharmacology actions of drugs on the body. Pharmacology Key Terms 3 The clinical purpose or pharmacotherapeutics reason for the medication The drug dose required potency to produce a specific intensity of effect. How readily the drug targets specific cells to selectivity produce an intended therapeutic effect. The effect of a drug, other than the desired side effect effect, sometimes in an organ other than the target organ. A measurement of the amount of drug that produces a therapeutic therapeutic index effect compared to the amount of drug that produces a toxic effect. The dosing window in which the safest and therapeutic window most effective treatment will occur. The trough level of medication indicates the lowest concentration of that medication in a person's body. Troughs trough of medication concentration occur after the drug has been broken down and metabolized by the body. Pharmacology Key Terms 4 Pharmacology Key Terms 5