Summary

This document contains a review of medications used for various conditions, including Graves' disease, hyperthyroidism, and cancer. It also discusses mechanisms and side effects of different drugs. The document appears to be study materials for a pharmaceutical exam.

Full Transcript

- This medication is used for Graves\' disease; hyperthyroidism; make sure to check liver function; assess clinical manifestation of hyperthyroidism. - **PROPYLTHIOURACIL -- PTU** - When you have clinical manifestations of hypertension; the medication for this is ketoconazole...

- This medication is used for Graves\' disease; hyperthyroidism; make sure to check liver function; assess clinical manifestation of hyperthyroidism. - **PROPYLTHIOURACIL -- PTU** - When you have clinical manifestations of hypertension; the medication for this is ketoconazole; mood swings, chubby face, moon face, humpback, and the cortisol levels are elevated. - **CUSHINGS DISEASE** - S/S: fever, tachycardia, agitation, restlessness, everything is elevated; associated with hyperthyroidism - **THYROID STORM** - Mechanism of which the body no longer needs a specific hormone stimulator - **NEGATIVE FEEDBACK** - This medication is used for cancer it increases neutrophils and increases leukocytes - FILGASTRIM - This medication is used for breast cancer; pregnancy category D; not for breastfeeding - Tamoxifen - This medication is given for cancer: non-Hodgkin's lymphoma, T cell lymphoma, Crohn's; but also given for psoriasis and rheumatoid arthritis - Methotrexate - This is what is secreted in the body in response to low blood sugar levels - Glucagon - give this medication for anemias; low red blood cells; also known as cyanocobalamin - B12 - With this medication watch for fevers and chills; monitor the liver; monitor the CBC; thyroid is working if patient begins to lose weight; used for hyperthyroidism - Methimazole - What does a body need to be able to absorb calcium - vitamin D3 - This plays a role in the synthesis of T3 and T4; used to suppress the thyroid before surgery - RADIOACTIVE IODINE I -131 - Which insulin do you give at hour of sleep to monitor blood sugar from dropping at night; long acting - Glargine (Lantis) - Intermediate acting; cloudy - NPH - when mixing insulin clear goes into cloudy - Regular insulin fast acting; used for sliding scale - Someone with DKA place them on what insulin drip - regular - only pharmacy can mix it - 1:1 ratio - Watch for low grade fever; can\'t handle any type of stress (They don\'t have enough cortisol to handle stress); they will need high doses of hydrocortisone because they have what? - ADDISON'S DISEASE - This is a disease process with autoimmune response - Hashimoto's disease (hypothyroidism) - Medication for Hashimoto's disease or hypothyroidism - Levothyroxine (micrograms not mg) - education for levothyroxine - give at 0600 to be able to digest - give same time every morning - wait one hour to eat - This is a diabetes medication; it can cause GI upset; it can cause lactic acidosis; hold if patient gets CT scan with contrast - METFORMIN - give this medication for acromegaly - OCTREOTIDE IV or PO - education for Octreotide - Constipation, don\'t be scared if stool is dark and tarry; take with iron supplements - Someone has cancer and needs to increase RBC production gets a shot to help stimulate body to produce more RBC - erythropoietin/epoetin alpha - Sure to watch for thrombolytic events - when taking iron supplements when is it administered - 1 hour before or 2 hours after meals - take with a full glass of water or juice - This stimulates neutrophil production for those patients who have low white blood cells due to cancer - COLONY STIMULATING FACTORS - Used for Hodgkin\'s Lymphoma; a cancer Med; serious side effect is tingling in hands and feet; pregnancy category D; neurotoxic - VINCRISTINE - This medication is cardiotoxic; 3-6 months after finishing medication your patient can experience heart failure; chemo medication; do not take if pregnant; cardiotoxic - DOXORUBICIN - This is responsible for glucose homeostasis in the body - INSULIN; GLUCAGON - What is generic name for NovoLog or Aspart - regular insulin (NovoLog & Aspart is brand name) - Acue checks are done four times a day - KNOW WHICH INSULIN IS INTERMIDIATE AND LONG LASTING - HYPOGLYCEMIA S/S COOL CLAMY, FATIGUE, DIAPHORTEIC - Group of medications for Type 2 diabetics; metformin is in this group - BIGUANIDE - This medication is given for endocrine issues; it can also be given for nighttime wetting (nocturia); GIVEN FOR DI; Hemophilia; this is a synthetic vasopressin - DESMOPRESSIN - The opposite of DI is SIADH - Give this for Adrenal Cortisol Insufficiency - COSYNTROPIN - Oral medication that increases glucose secretion in the urine - DAPAGLIFLOZIN (FARXIGA) - Medication given for hypothyroid; given NPO; must take for the rest of your life - LEVOTHYROXINE

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