Pharm EXAM 3.pdf

Pharm Exam 3 HF and Study online at https://quizlet.com/_fy6ydl Right Sided HF Dependent edema; vein distention; fluid retention Left-sided HF (most common...

Pharm Exam 3 HF and Study online at https://quizlet.com/_fy6ydl Right Sided HF Dependent edema; vein distention; fluid retention Left-sided HF (most common) from left ventricular dysfunction (e.g., MI hypertension, CAD, cardiomyopathy) Left Sided HF Backup of blood into the left atrium and pulmonary veins Pulmonary congestion The precontraction pressure in the heart as the volume of blood Preload builds up. Afterload The amount of resistance to ejection of blood from the ventricle Statin MOA Inhibit HMG-CoA reductase Reduce the production of LDL (Low density lipoprotein) in the liver; Statins are used for? High cholesterol Statins Complications Hepatotoxicity, rhabdomyolysis You should report muscle aches, rust colored urine, and pain with. Statins Binds to bile acid to limit the reabsorption of bile acids in the Cholestyramine MOA gastrointestinal tract. Cholestyramine is used to. Reduce serum cholesterol and LDL Cholestyramine must be given in 60-80mls of liquid and must be 2 hours before medications OR 4 hours after medications given around. Gemfibrozil MOA Breaks down TG particles Gemfibrozil is used for what? High cholesterol. It increases HDL and reduces VLDL Gemfibrozil can cause what? Gallstones, GI Distress, and affect Liver Function Ezetimibe MOA Inhibits absorption of cholesterol in small intestine Ezetimibe is used to? Lower Cholesterol Ezetimibe can cause what? Angioedema Alirocumab MOA PCSK9 inhibitor --> binds to LDL receptors on the liver. Alirocumab is used for what? Hypercholesterolemia Alirocumab is administered through witch route. SUBQ Alirocumab can cause? Flu like symptoms. Captopril, Lisinopril, and Enalapril are all examples of what? ACE-1 Inhibitors Reducing BP and reducing afterload and preload improving car- ACE-1 Inhibitors and ARB work by? diac output. ACE-1 Inhibitors can cause? Dizziness, Orthostatic Hypotension, and Cough Losartan is an example of a? ARB Furosemide, Thiazides, and Spironolactone treat HF by? Removing excess fluid prevent HF exacerbation. Beta Blockers like Metoprolol and Carvedilol work by? Slowing the HR and decreasing the BP afterload Carvedilol is contraindicated with what condition? Asthma, and bronchospastic disorders Digoxin is an example of a? cardiac glycoside increased contractions and force of heart which decreases heart Digoxin works by? rate Before administering a beta blocker and a glycoside you should BP and HR check? Visual Halos, Yellow-Green Tinged or Blurred Vision, and Anorex- What are some Digoxin toxicity cues? ia. Hydralazine and Isosorbide are examples of? Vasodilators Hydralazine and Isosorbide can cause what? Reflex Tachycardia, and Orthostatic Hypotension Milrinone is normally given via? IV Milrinone can cause what? Dysrhythmias and must be placed on a cardiac monitor and BP. 1/3  Pharm Exam 3 HF and Study online at https://quizlet.com/_fy6ydl Milrinone is normally used in? Advanced HF and exacerbations Monitor weight and report an increase of 2 lbs a day or 5 lbs a What are some nursing considerations for managing HF? week. SpO2 of 92%