PHARM CH2.pptx
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CHAPTER 2: ROUTES AND TECHNIQUES OF DRUG ADMINISTRATION Introduction The Technician’s Role Administer proper treatment to patient Document medical record Observe patient response to tx Dosage Forms - Oral Forms Tablets – scored vs unscored, enteric coating Capsules Boluses Liq...
CHAPTER 2: ROUTES AND TECHNIQUES OF DRUG ADMINISTRATION Introduction The Technician’s Role Administer proper treatment to patient Document medical record Observe patient response to tx Dosage Forms - Oral Forms Tablets – scored vs unscored, enteric coating Capsules Boluses Liquids suspension: preparation of solid particles dispersed in a liquid but not dissolved in it syrups: contain the drug and flavoring in a solution of sugar water or other aqueous liquid elixirs: hydroalcoholic liquid that contains sweeteners, flavoring and a medicinal agent emulsions: oily substances dispersed in an aqueous medium w/ an additive that stabilizes the mixture Dosage Forms - Oral Factors which influence absorption Species & individual differences pH of the drug Solubility of drug Size & shape of molecule Presence or absence of food in the GI tract GI motility Presence & nature of any disease processes Dosage Forms – Parenteral Forms Injectable – IV, IM, SC, ID, IP, IA, IC, intraarticular, intramedullary, epidural/subdural Implants – hard sterile pellets that contain a chemical or hormonal agent Syringes & needles – sterile, various sizes & shapes, used needles discarded in sharps container Do not store drugs in syringes Dosage Forms - Parenteral Reconstitution of a Medication Syringes and Needles Dosage Forms - Topical Preparations Sublingual Uterine Vaginal Rectal Ophthalmic Otic Transdermal Dosage Forms - Topical Liniments: medicinal preparation in an oily, soapy, or alcoholic vehicle to be rubbed on the skin to relieve pain or act as a counterirritant Ointment: semisolid preparation of oil and water that contains a medicinal agent(s) for application to the skin or eyes Cream: semisolid preparation of oil, water and a medicinal agent Lotions: liquid suspensions or solutions with soothing substances for application to the skin Powders: drugs in powder form mixed with an adsorbent (corn starch) or lubricant (talcum) Aerosols: drugs incorporated into a solvent and packaged under pressure with a propellant Dosage Forms Microencapsulation – process in which an active ingredient is contained in microcapsules Uses Stabilize substances commonly considered unstable Provide slow release of a drug Mask flavor of a drug Drug Preservatives and Solvents Organic or inorganic additives or pharmaceutic aids Inactive/inert ingredients Can cause adverse effects Drug Administration The 5 Rights Right patient Right drug – check label 3 times Right dose Right route Right time & frequency Drug Administration - Oral Easy to administer Slow onset, longer duration of action Mucosa of GI tract has large surface area and rich blood supply Not suitable for animals w/ V/D Drug Administration - Oral Pet Piller Balling gun Drug Administration - Oral Nasogastric admin. using a stomach tube Orogastric admin. using a Frick’s speculum & stomach tube Drug Administration Parenteral IV – most rapid onset of action and shortest duration Route used for irritating medications Give slow to lessen possibility of toxic or allergic rxn Thick or cloudy medications usually NOT given this route Sites of admin. – cephalic v., jugular v., lateral saphenous v. Multiple doses may require IV catheter Drug Administration Parenteral IM – slower onset of action and longer duration of action Avoid vv., aa. & nn. Depot preparations SQ –slowest onset of action and longest duration of action Hypodermoclysis: refers to admin. of SQ fluids Hyaluronidase: enzyme added to drug to speed absorption ID – TB & allergy testing IP, IA, IC, intraarticular, intramedullary, epidural and subdural/intrathecal Anatomy Review Drug Administration Parenteral Common complications – irritation, necrosis, infection at injection site and allergic rxns Clinical signs of an allergic rxn Swelling around face or extremities Raised bumps or swellings on skin Edema Salivation Drug Administration Inhalation medications Vaporizer – part of anesthetic machine which converts inhalant in liquid form to gas which is then delivered via endotracheal tube, mask or induction chamber Nebulizer –apparatus for reducing liquids to a fine spray, as for medicinal administration Topical medications Skin – clip hair Eyes – multiple applications per day Ears – clean prior to medicating Medication Orders Written or Oral Abbreviations – Appendix A Includes patient info, amount of drug, route of admin., frequency and duration Record, record, record!!! Medication Orders Sample medical record treatment entry made by LVMT. Medication Orders Sample medical record presciption entry made by LVMT. Controlled Substances Substances that have the ability to become habit forming DEA requires Unmovable locked area Inventory log Label – “Caution: Federal law prohibits the transfer of this drug to any person other than the patient for whom it was prescribed.” Client Education How to administer Why prescribed Possible adverse reactions Proper storage