Objective_Answers_Compilation.csv

Objective,Answer Define long-term steroid use.,Long-term steroid use is defined as use exceeding 14 days at doses equivalent to prednisone \> 5 mg daily. Describe the structure and function of the adrenal gland including the secretions specific to each cortex layer.,"The adrenal gland consists of th...

Objective,Answer Define long-term steroid use.,Long-term steroid use is defined as use exceeding 14 days at doses equivalent to prednisone \> 5 mg daily. Describe the structure and function of the adrenal gland including the secretions specific to each cortex layer.,"The adrenal gland consists of three cortex layers: zona glomerulosa (produces aldosterone), zona fasciculata (produces cortisol), and zona reticularis (produces androgens). Each layer secretes specific hormones regulating metabolism, immune response, and electrolyte balance." Explain the rationale for corticosteroids in adrenal insufficiency treatment.,"Corticosteroids are used in adrenal insufficiency to replace deficient cortisol, essential for metabolic and immune functions." "Describe the presentation of Cushing's syndrome, adrenal insufficiency, hyperaldosteronism, and hyperprolactinemia.","Cushing's syndrome presents with hypercortisolism symptoms (e.g., obesity, skin changes), adrenal insufficiency with cortisol deficiency symptoms (e.g., fatigue, low BP), hyperaldosteronism with hypertension and hypokalemia, and hyperprolactinemia with galactorrhea." Describe the pathophysiology of adrenal insufficiency.,"Adrenal insufficiency pathophysiology involves cortisol deficiency due to adrenal gland dysfunction, leading to compensatory ACTH elevation and associated symptoms of fatigue and electrolyte imbalance." Describe complications of Cushing's syndrome.,"Complications of Cushing's syndrome include osteoporosis, diabetes, cardiovascular disease, and increased infection risk due to prolonged high cortisol levels." Identify the role of corticosteroids in treatment of Adrenal Insufficiency.,Corticosteroids in adrenal insufficiency serve as hormone replacement to manage symptoms caused by deficient adrenal production of cortisol. Describe adrenal crisis and its causes.,"Adrenal crisis, an acute deficiency of cortisol, can be triggered by stress or abrupt steroid withdrawal and requires immediate corticosteroid treatment." "List agents used for treatment of Cushing's syndrome, adrenal insufficiency, adrenal crisis, hyperaldosteronism, and hyperprolactinemia.","Agents for treatment include metyrapone for Cushing's syndrome, hydrocortisone for adrenal insufficiency and crisis, spironolactone for hyperaldosteronism, and cabergoline for hyperprolactinemia." Identify pharmacologic classification of adrenal drugs.,"Adrenal drugs are classified based on their actions as glucocorticoids, mineralocorticoids, or anti-adrenal agents."