Molecular Genetics PDF
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Summary
This document covers core concepts in molecular genetics. It defines the genome and chromosome, explaining their roles in storing and transmitting genetic information. Key topics include DNA structure, the genetic code, and the processes involved in cell division.
Full Transcript
Molecular genetics - chromosomes...
Molecular genetics - chromosomes are only visible during cell division. because DNA exists usually · Genome in losse-thread like structure but - a genome is all the genetic during cell division , DNA coils up material of which makes it visible an organism.. All the DNA inside one cell is called the Chromatin DNA structural proteins. genome ·. : + So DNA when it's , chromatin is basically DNA is stored inside our chrom- in it's lose thread like form and wrap - · somes but there is also DNA ped around histone proteins. (DNA exists in our mitochondria. So all of that as chromatin most of the time , except combined is the for when the cell about to divide -> genome. is then chromatin coils up into a chromo- found Genome is cell in body ) · in every our some. base- - & - mitochondria DNA pairs & 3 nuclear DNA Genome a - · The genome includes , base pairs , DNA Pie strands , DNA double helix , Nucleotide , histone proteins nucleosome , chromatin , chrosomeses and Chromosome it's coiled genes tightly ·. : a version S of chromatin it's DNA-mole. a very long all of these make up the wrapped around each other. genome , cule > - is not molecule it's genome - a just concept that includes all & a this. It's Like collection of genetic · material. It provides all the information required for to function a exists two form single organism an chromosome i , and develop S chromosome which is unreplicated and summary : A genome is all the genes an individual * - shaped chromosome (replicated form) · cell has eukaryotes : nucleus - a chromatid is one half of a duplicated nucleoid refers to single strand Prokaryotes : region chromosome. a not Chromosome · connected to another chromatid ~ * chromosome thread-like is long · a a structure that is made up of DNA and proteins. in eukaryotic # Centromere ↑ cells DNA is coiled · sister chromatids is then the two · chromosomes are located in- up inside them identical copies of a chromosome that side of the nucleus each cell in our body. - are made when DNA is replicated , they - we have 46 chromosomes in the nucleus and are joined by a centromere. always come - each one of them has a DNA molecule inside in pairs. centromere them. - held by centro- mere information chromosomes carry genetic - no In in the form of genes. I code for specific sister. Sister chromatid chromatid proteins location ~ · Order of chromosome chromatin etc. · Locus it's a location of gene , : a on a chromosome. So would be located gene a on a locus it's like address of a , an gene , Chromatin > chromosome - > helps you locate a chromosome. gene on - a o Different alleles of exist 3 at the a gene can same locus. chromatid called chromatid ene for blue eyes ~ 9 o - * when separate different ↓ * , of locus eye chromosomes. Color gene. Sister chromatids - same chromosome - called Sister chromatids > - chromatin (in daughter cell) · Homologous chromosomes : - similar in Shape/size Homologous chromosomes they pairs of each locus is in the same position - : are chromosomes that the same for the. trait carry genes carry genes - same in the order but have different same may alleles (alleles different forms of Genetic inform -. are the code : contains all - the genetic the of color has ation needed to control the cells activity gene ex same. gene eye. different alleles , blue eyes or green eyes) The genetic code has three letter nucleotides We inherit different alleles from each parent. that are called codons (it's a sequence of - we have chromosomes in cell expect the sex three nucleotides that code for specific amino every cells which are also called gamets. acid) The genetic code has 64 codons. 61 codons - we have 22 pairs of chromosomes that are are for amino acid and 3 for stop/start. autosomes (they don't determine the sex , they contain genes for ex eye color , height etc). We have 2 pair of sex chromosoms that determine the sex. · Genes a chromosome of & - a gene is a small section in DNA , & that is made up of a sequence of nucleotides (A-T-C-G) Genes contain (1. the information to code for specific proteins (proteins are responsible for traits like height , eye color etc. ) this of nucleotids act code. sequence as a thisiscalledage productits t the · Dut In - alleles are different versions of the same (blue eyes). characteristic. us brown We have 20-25 000 , genes. - Nucleotide. - don Genetic code = contains all the information to necessary control the cell's activities. Karystype ? Histones ? Diploid organism ? Diploid ? individuals ? haploid ?! Nucleosome ? ? homogoulus chromosomes