Module 10: The Circulatory System PDF

Summary

This document describes the circulatory system, including diffusion, gastrovascular cavities, and different types of circulatory systems. It also explains the organization of vertebrate circulatory systems and the three main types of blood vessels.

Full Transcript

‭MODULE 10: THE CIRCULATORY SYSTEM‬ ‭ losed‬ ‭Circulatory‬ ‭System:‬ ‭Blood‬ ‭is‬ ‭confined‬ ‭to‬ C ‭vessels and is dist...

‭MODULE 10: THE CIRCULATORY SYSTEM‬ ‭ losed‬ ‭Circulatory‬ ‭System:‬ ‭Blood‬ ‭is‬ ‭confined‬ ‭to‬ C ‭vessels and is distinct from the interstitial fluid.‬ ‭ irculatory‬‭systems‬‭link‬‭exchange‬‭surfaces‬‭with‬‭cells‬ C ‭‬ ‭Annelids, cephalopods, and vertebrates‬ ‭throughout the body‬ ‭ iffusion:‬ ‭It‬ ‭is‬ ‭a‬ ‭process‬ ‭by‬ ‭which‬ ‭small‬ ‭molecules‬ D ‭can‬‭move‬‭between‬‭cells‬‭and‬‭their‬‭surroundings‬‭(O‬‭2‬ ‭and CO‬‭2‬‭).‬ I‭t‬ ‭is‬ ‭only‬ ‭efficient‬‭over‬‭small‬‭distances‬‭because‬‭the‬ ‭time‬ ‭it‬ ‭takes‬‭to‬‭diffuse‬‭is‬‭proportional‬‭to‬‭the‬‭square‬ ‭of the distance.‬ I‭n‬ ‭small‬ ‭or‬ ‭thin‬ ‭animals,‬ ‭cells‬ ‭can‬ ‭exchange‬ ‭ORGANIZATION OF VERTEBRATE CIRCULATORY‬ ‭materials directly with the surrounding medium.‬ ‭SYSTEMS‬ ‭The‬‭cardiovascular system‬‭:‬ I‭n‬ ‭most‬ ‭animals,‬ ‭cells‬ ‭exchange‬ ‭materials‬ ‭with‬ ‭the‬ ‭‬ ‭Closed‬ ‭circulatory‬ ‭system‬ ‭in‬ ‭humans‬ ‭and‬ ‭environment via a fluid-filled circulatory system.‬ ‭other vertebrates‬ ‭‬ ‭Blood flow is one way‬‭in these vessels‬ ‭ ASTROVASCULAR CAVITIES‬ G ‭It‬ ‭functions‬ ‭in‬ ‭both‬ ‭digestion‬ ‭and‬ ‭distribution‬ ‭of‬ ‭There are‬‭three main types of blood vessels‬‭:‬ ‭substances‬‭throughout the body.‬ ‭ rteries:‬ ‭These‬ ‭branch‬ ‭into‬ ‭arterioles‬ ‭and‬ ‭carry‬ A T‭ he‬ ‭body‬ ‭wall‬ ‭that‬ ‭encloses‬ ‭the‬ ‭gastrovascular‬ ‭blood away from the heart to capillaries.‬ ‭cavity is‬‭only two cells thick‬‭.‬ ‭ apillaries:‬ ‭Sites‬ ‭of‬ ‭chemical‬ ‭exchange‬ C S‭ ome‬ ‭cnidarians‬ ‭have‬ ‭elaborate‬ ‭gastrovascular‬ ‭between the blood and interstitial fluid.‬ ‭cavities.‬ ‭Veins:‬‭Return blood from capillaries to the heart.‬ F‭ latworms‬ ‭have‬ ‭a‬ ‭gastrovascular‬ ‭cavity‬ ‭and‬ ‭a‬‭flat‬ ‭body‬‭that minimizes diffusion distances.‬ ‭ rteries‬‭and‬‭veins‬‭are‬‭distinguished‬‭by‬‭the‬‭direction‬ A ‭of blood flow‬‭, not by O‬‭2‬ ‭content.‬ ‭Some animals lack a circulatory system.‬ ‭Vertebrate hearts contain‬‭two or more chambers‬‭.‬ T‭ HE CIRCULATORY SYSTEMS‬ ‭‬ ‭Blood‬ ‭enters‬ ‭through‬ ‭an‬ ‭atrium‬ ‭and‬ ‭is‬ ‭It‬ ‭connects‬ ‭the‬ ‭fluid‬ ‭that‬ ‭surrounds‬ ‭cells‬ ‭with‬ ‭the‬ ‭pumped out through a ventricle.‬ ‭organs‬‭that‬‭exchange‬‭gasses,‬‭absorb‬‭nutrients,‬‭and‬ ‭dispose of waste.‬ ‭ ‬ ‭circulatory‬ ‭system‬ ‭has:‬ ‭(1)‬ ‭circulatory‬ ‭fluid,‬ ‭(2)‬ A ‭interconnecting‬ ‭vessels,‬ ‭and‬ ‭(3)‬ ‭a‬ ‭pump,‬ ‭which‬ ‭is‬ ‭the heart.‬ ‭ pen‬ ‭Circulatory‬ ‭System:‬ ‭Circulatory‬ ‭fluid‬ ‭called‬ O ‭hemolymph‬‭bathes the organs directly.‬ ‭‬ ‭It‬ ‭is‬ ‭found‬ ‭in‬ ‭insects,‬ ‭other‬ ‭arthropods,‬ ‭and‬ ‭molluscs.‬ ‭8‬ ‭TYPES OF CIRCULATION‬ ‭ ingle‬ ‭Circulation:‬ ‭Blood‬ ‭leaving‬ ‭the‬ ‭heart‬ ‭passes‬ S ‭through two capillary beds‬‭before returning.‬ ‭ ony‬ ‭fishes,‬ ‭rays,‬‭and‬‭sharks‬‭have‬‭single‬‭circulation‬ B ‭with a‬‭two-chambered heart‬‭.‬ ‭ volutionary Variation in Double Circulation‬ E ‭Some‬ ‭vertebrates‬ ‭with‬ ‭double‬ ‭circulation‬ ‭are‬ ‭intermittent‬ ‭breathers.‬ ‭Amphibians‬ ‭and‬ ‭many‬ ‭reptiles‬ ‭may‬ ‭pass‬ ‭long‬ ‭periods‬ ‭without‬ ‭gas‬ ‭exchange,‬ ‭or‬ ‭relying‬ ‭on‬ ‭gas‬ ‭exchange‬ ‭from‬ ‭another tissue, usually the skin.‬ ‭ ouble‬ ‭Circulation:‬ ‭Oxygen-poor‬ ‭and‬ ‭Oxygen-rich‬ D ‭blood‬ ‭are‬ ‭pumped‬ ‭separately‬ ‭from‬ ‭the‬ ‭right‬ ‭and‬ ‭Frogs and other amphibians:‬ ‭left sides of the heart.‬ ‭‬ ‭Have‬ ‭a‬ ‭three-chambered‬ ‭heart‬‭:‬ ‭two‬ ‭atria‬ ‭and one ventricle‬ I‭t‬ ‭maintains‬ ‭higher‬ ‭blood‬ ‭pressure‬ ‭in‬ ‭the‬ ‭organs‬ ‭‬ ‭The‬ ‭ventricle‬ ‭pumps‬ ‭blood‬ ‭into‬ ‭a‬ ‭forked‬ ‭than it does in single circulation.‬ ‭artery‬ ‭that‬ ‭splits‬ ‭the‬ ‭ventricle’s‬ ‭output‬ ‭into‬ ‭the‬ ‭pulmocutaneous‬ ‭circuit‬ ‭and‬ ‭the‬ ‭It is found in amphibians, reptiles, and mammals.‬ ‭systemic circuit.‬ ‭‬ ‭When‬‭underwater,‬‭blood‬‭flow‬‭to‬‭the‬‭lungs‬‭is‬ ‭In‬‭amphibians‬‭:‬ ‭nearly shut off‬‭.‬ ‭‬ ‭Oxygen-poor‬ ‭blood‬ ‭flows‬ ‭through‬ ‭a‬ ‭pulmocutaneous‬ ‭circuit‬ ‭to‬ ‭pick‬ ‭up‬ ‭oxygen‬ ‭through the lungs and skin.‬ ‭‬ ‭Oxygen-rich‬ ‭blood‬ ‭delivers‬ ‭oxygen‬ ‭through‬ ‭the systemic circuit‬‭.‬ ‭9‬ ‭Mammals & birds:‬ ‭‬ ‭Endotherms‬ ‭that‬ ‭require‬ ‭more‬ ‭O‭2‬ ‬ ‭than‬ ‭ectotherms‬ ‭‬ ‭Separation‬ ‭of‬ ‭deoxygenated‬ ‭and‬ ‭oxygenated blood‬ ‭‬ ‭Septum is fully formed.‬ ‭‬ ‭Have‬ ‭a‬ ‭four-chambered‬ ‭heart‬‭;‬ ‭two‬ ‭atria‬ ‭and two ventricles‬ ‭‬ ‭The‬ ‭left‬ ‭side‬ ‭of‬ ‭the‬ ‭heart‬ ‭pumps‬ ‭and‬ ‭receives‬‭only oxygen-rich blood‬‭.‬ ‭‬ ‭The‬ ‭right‬ ‭side‬ ‭of‬ ‭the‬ ‭heart‬ ‭receives‬ ‭and‬ ‭pumps‬‭only oxygen-poor blood‬‭.‬ ‭Turtles, snakes, & lizards:‬ ‭‬ ‭Have‬ ‭a‬ ‭three-chambered‬ h ‭ eart‬‭:‬ ‭two‬ ‭atria‬ ‭and one ventricle‬ ‭‬ ‭It‬ ‭is‬ ‭partially‬ ‭divided‬ ‭by‬ ‭an‬ ‭incomplete‬ ‭septum‬‭.‬ ‭MAMMALIAN CIRCULATION‬ ‭Alligators, caimans, & other crocodilians:‬ ‭‬ ‭A‬ ‭septum‬ ‭divides‬ ‭the‬ ‭ventricles‬ ‭but‬ ‭pulmonary‬ ‭and‬ ‭systemic‬ ‭circuits‬ ‭connect‬ ‭where the arteries exit‬‭the heart.‬ ‭10‬ (‭ 1)‬ ‭The‬‭right‬‭ventricle‬‭pumps‬‭blood‬‭to‬‭the‬‭lungs‬‭via‬ T‭ he‬ ‭Atria‬ ‭(Atrium):‬ ‭It‬ ‭has‬ ‭thin‬ ‭walls.‬ ‭It‬ ‭serves‬ ‭as‬ ‭pulmonary arteries.‬ ‭collection‬ ‭chambers‬ ‭for‬ ‭blood‬ ‭returning‬ ‭to‬ ‭the‬ ‭heart‬‭.‬ (‭ 2)‬ ‭In‬ ‭the‬ ‭lungs‬‭,‬ ‭the‬ ‭blood‬ ‭loads‬ ‭O‭2‬ ‬ ‭and‬ ‭unloads‬ ‭CO‬‭2‬‭.‬ T‭ he‬ ‭Ventricles:‬ ‭It‬ ‭has‬ ‭thicker‬ ‭walls‬ ‭and‬ ‭contracts‬ ‭much‬ ‭more‬ ‭forcefully.‬ ‭It‬ ‭pushes‬ ‭blood‬ ‭out‬ ‭of‬ ‭the‬ (‭ 3)‬‭Oxygen-rich‬‭blood‬‭from‬‭lungs‬‭enters‬‭the‬‭heart‬‭at‬ ‭heart to the heart.‬ ‭the‬‭left‬‭atrium‬‭via‬‭pulmonary‬‭veins‬‭.‬‭(4)‬‭It‬‭is‬‭pumped‬ ‭through‬ ‭the‬ ‭aorta‬ ‭to‬ ‭the‬ ‭body‬ ‭tissues‬ ‭by‬ ‭the‬ ‭left‬ T‭ he Cardiac Cycle‬ ‭ventricle‬‭.‬ ‭The heart contracts and relaxes in a rhythmic cycle.‬ (‭ 5)‬ ‭The‬ ‭aorta‬ ‭provides‬ ‭blood‬ ‭to‬ ‭the‬ ‭heart‬ ‭through‬ ‭Systole:‬‭Contraction or pumping phase‬ ‭the‬‭coronary arteries‬‭.‬ ‭Diastole:‬‭Relaxation or filling phase‬ (‭ 9‬ ‭&‬ ‭10)‬‭Blood‬‭returns‬‭to‬‭heart‬‭through‬‭the‬‭superior‬ ‭vena‬ ‭cava‬ ‭(from‬ ‭head,‬ ‭neck,‬ ‭&‬ ‭forelimbs)‬ ‭and‬ ‭Heart rate:‬‭Number of of beats per minute‬ ‭inferior vena cava‬‭(from trunk & hind limbs).‬ ‭The SVC and IVC flow into the‬‭right atrium‬‭.‬ I‭n summary:‬ ‭Oxygenated Blood‬ ‭Right‬ ‭ventricle‬ ‭(deoxygenated)‬ ‭→‬ ‭Lungs‬ ‭→‬ ‭Pulmonary‬ ‭Veins‬ ‭→‬ ‭Left‬ ‭Atrium‬ ‭→‬ ‭Left‬ ‭Ventricle‬ ‭→‬ ‭Aorta → Body Tissues & Heart‬ ‭Deoxygenated Blood‬ ‭ lood‬ ‭from‬ ‭head,‬ ‭neck,‬ ‭&‬ ‭forelimbs‬ ‭→‬ ‭Superior‬ B ‭Vena‬ ‭Cava‬ ‭(SVC)‬ ‭→‬ ‭Right‬ ‭Atrium‬ ‭→‬ ‭Heart‬ ‭(right‬ ‭ventricle)‬ ‭←‬ ‭Right‬ ‭Atrium‬ ‭←‬ ‭Inferior‬ ‭Vena‬ ‭Cava‬ ‭(IVC) ← Blood from trunk & hind limbs‬ ‭THE MAMMALIAN HEART‬ T‭ here‬ ‭are‬ ‭four‬ ‭valves‬ ‭in‬ ‭the‬ ‭heart‬ ‭that‬ ‭prevent‬ ‭backflow of blood‬‭in the heart.‬ ‭‬ ‭Atrioventricular‬ ‭Valves‬‭:‬ ‭between‬ ‭atrium‬ ‭&‬ ‭ventricles‬ ‭‬ ‭Semilunar‬ ‭Valves‬‭:‬ ‭between‬ ‭right‬‭ventricle‬‭&‬ ‭pulmonary‬‭artery‬‭(right‬‭side),‬‭left‬‭ventricle‬‭&‬ ‭aorta (left side)‬ ‭ aintaining the Heart’s Rhythmic Beat‬ M ‭Cardiac‬ ‭muscle‬ ‭cells‬ ‭are‬ ‭autorhythmic‬‭,‬ ‭meaning‬ ‭they‬ ‭contract‬ ‭without‬ ‭any‬ ‭signal‬ ‭from‬ ‭the‬ ‭nervous‬ ‭system.‬ ‭11‬ ‭ inoatrial‬ ‭(SA)‬ ‭Node:‬ ‭Also‬ ‭called‬ ‭pacemaker,‬ ‭sets‬ S ‭the‬ ‭rate‬ ‭and‬ ‭timing‬ ‭at‬ ‭which‬ ‭cardiac‬ ‭muscle‬‭cells‬ ‭contract.‬ ‭ lectrocardiogram‬ ‭(ECG‬ ‭or‬ ‭EKG):‬ ‭It‬ ‭can‬ ‭record‬ E ‭impulses that travel during the cardiac cycle.‬ ‭ LOOD COMPOSITION & FUNCTION‬ B ‭Blood‬ ‭is‬ ‭a‬ ‭connective‬ ‭tissue‬ ‭consisting‬ ‭of‬ ‭several‬ ‭kinds‬ ‭of‬ ‭cells‬ ‭suspended‬ ‭in‬ ‭a‬ ‭liquid‬ ‭matrix‬ ‭called‬ ‭plasma‬‭.‬ ‭ lasma:‬ ‭It‬‭contains‬‭inorganic‬‭salts‬‭as‬‭dissolved‬‭ions,‬ P ‭sometimes called‬‭electrolytes‬‭.‬ ‭ lasma‬ ‭proteins‬ ‭influence‬ ‭blood‬ ‭pH‬ ‭and‬ ‭help‬ P ‭maintain‬ ‭osmotic‬ ‭balance‬ ‭between‬ ‭and‬‭interstitial‬ ‭fluid.‬ ‭ articular‬‭plasma‬‭proteins‬‭function‬‭in‬‭lipid‬‭transport,‬ P ‭immunity, and blood clotting.‬ ‭ rythrocytes‬ ‭(Red‬ ‭Blood‬ ‭Cells):‬ ‭It‬ ‭is‬ ‭the‬ ‭most‬ E ‭numerous‬‭blood‬‭cell.‬‭It‬‭contains‬‭Hemoglobin‬‭(Hgb),‬ ‭the‬‭iron-containing protein that transports O‬‭2‭.‬ ‬ I‭n‬ ‭mammals,‬ ‭mature‬ ‭RBCs‬ ‭l‬‭ack‬ ‭nuclei‬ ‭and‬ ‭mitochondria‬‭.‬ ‭ latelets:‬ ‭Fragments‬ ‭of‬ ‭cells‬ ‭and‬ ‭function‬ ‭in‬ ‭blood‬ P ‭clotting.‬ L‭ eukocytes‬ ‭(White‬ ‭Blood‬ ‭Cells):‬ ‭It‬ ‭is‬ ‭mainly‬ ‭for‬ ‭defense‬ ‭either‬ ‭by‬ ‭phagocytizing‬ ‭bacteria‬ ‭and‬ ‭debris‬ ‭(rest‬ ‭of‬ ‭WBCs)‬ ‭or‬ ‭by‬ ‭mounting‬ ‭immune‬ ‭ ellular‬‭elements‬‭occupy‬‭about‬‭45%‬‭of‬‭the‬‭volume‬ C ‭responses‬ ‭against‬ ‭foreign‬‭substances‬‭(lymphocytes‬ ‭of blood.‬ ‭only).‬ I‭t‬ ‭is‬ ‭found‬ ‭both‬ ‭in‬ ‭and‬ ‭outside‬ ‭of‬ ‭the‬ ‭circulatory‬ ‭system.‬ ‭12‬ T‭ here‬ ‭are‬ ‭five‬ ‭major‬ ‭types:‬ ‭(1)‬ ‭monocytes,‬ ‭(2)‬ ‭neutrophils,‬ ‭(3)‬ ‭basophils,‬ ‭(4)‬ ‭eosinophils,‬ ‭and‬ ‭(5)‬ ‭lymphocytes.‬ ‭BLOOD CLOTTING (COAGULATION)‬ ‭It is the‬‭formation of a solid clot from liquid blood‬‭.‬ ‭ ‬‭cascade‬‭of‬‭reactions‬‭converts‬‭inactive‬‭fibrinogen‬ A ‭to fibrin‬‭, forming a clot.‬ ‭ ‬ ‭blood‬ ‭clot‬‭formed‬‭within‬‭a‬‭blood‬‭vessel‬‭is‬‭called‬ A ‭a‬‭thrombus‬‭and can block blood flow.‬ ‭ 1:‬ ‭The‬ ‭enzymatic‬ ‭cascade‬ ‭performed‬ ‭by‬ ‭clotting‬ # ‭factors‬ ‭(platelets,‬ ‭damaged‬ ‭cells,‬ ‭&‬ ‭plasma)‬ ‭initiates the‬‭conversion of prothrombin to thrombin‬‭.‬ ‭#2:‬‭Thrombin converts fibrinogen to fibrin.‬ ‭#3:‬‭Clot formation is initiated.‬ T‭ his‬ ‭is‬ ‭a‬ ‭positive‬ ‭feedback‬ ‭loop.‬ ‭This‬ ‭is‬ ‭due‬ ‭to‬ ‭the‬ ‭enzymatic‬ ‭cascade‬ ‭initiation‬ ‭of‬ ‭the‬ ‭conversion‬ ‭of‬ ‭prothrombin‬ ‭to‬ ‭thrombin.‬ ‭Thrombin‬ ‭then‬ ‭also‬ ‭increases the stimulus of the enzymatic cascade.‬ ‭13‬

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