Metabolism Tables.pptx

ANABOLIC PATHWAYS Purpose Location Gluconeogenesis Gluconeogenes is Glycogenesis Glycogenesis Makes glucose from precursor molecules Mitochondri a and cytosol Makes glycogen to store glucose Cytosol FattyFatty acid synthesis Acid Makes fatty acids from acetyl CoA Cytosol Adds fatty acids...

ANABOLIC PATHWAYS Purpose Location Gluconeogenesis Gluconeogenes is Glycogenesis Glycogenesis Makes glucose from precursor molecules Mitochondri a and cytosol Makes glycogen to store glucose Cytosol FattyFatty acid synthesis Acid Makes fatty acids from acetyl CoA Cytosol Adds fatty acids to a glycerol backbone to make triglyceride lipids Cytosol Ketogenesis Makes ketone bodies from acetyl CoA Mitochondri a Pentose Phosphate ShuntPentose (PPS) Shunts glucose into the creation of various 5carbon sugars and NADPH Cytosol Synthesis Lipogenesis/ Lipogenesis triglyceride synthesis Ketogenesis Phosphate Shunt CATABOLIC PATHWAYS Purpose Location Glycogenolysis Breakdown of glycogen to release glucose. Glucose can then enter glycolysis to produce energy. Cytosol Breakdown of glucose to pyruvate to produce energy (NADH, ATP). After glycolysis, pyruvate can be converted to acetyl CoA to enter the CAC to produce more energy. Cytosol Glycogeno lysis Glycolysi Glycolysis s Lipolysis Lipolysis Beta Beta oxidation oxidation Ketolysis Breakdown of lipids (triglycerides) to release fatty acids from the glycerol backbone. The fatty acids can then enter beta oxidation to produce more energy. Breakdown of fatty acyls to acetyl CoA to produce energy (NADH, FADH2). Acetyl CoA can enter the CAC to produce more energy. Ketolysis/ketone Breakdown of ketone bodies to acetyl CoA. body oxidation Acetyl CoA can enter the CAC to produce more energy. Citric Krebs Acid Acid Cycle/Citric Breakdown of citrate (made from acetyl CoA and oxaloacetate) to produce energy (NADH, Mitochondri a Mitochondri a Mitochondri a