Summary

This document provides a list of medications, including their dosages, actions, adverse reactions, and contraindications. The document lists various classes of medications like anti-hypertensives, anti-anginals, and others. Information for each medication is presented in table format.

Full Transcript

MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Dosage Action Adverse Reaction Contraindications Name Anti-Hypertensives...

MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Dosage Action Adverse Reaction Contraindications Name Anti-Hypertensives  Blocks binding of  Dizziness  Hypersensitivity angiotensin II to  Headache  Renal or heart disease Diovan Valsartan receptor sites  Insomnia  2nd & 3rd Trimester  Fatigue (pregnancy)  Vertigo  Breast feeding  Hypotension  Diarrhea  Nausea  Abdominal Pain  Blocks beta  Dizziness  Hypersensitivity to drug Apo-Atenolol Atenolol adrenergic receptors,  Fatigue  Sinus bradycardia (Tenormin)  ↓ cardio output &  Hypotension  Overt cardiac failure CO2 consumption  Nausea  Cardiogenic Shock (BETA  Depresses renin  Diarrhea BLOCKER) secretion With-hold if pulse is < 60bpm  Blocks both Alpha &  Dizziness  Hypersensitivity to drug Coreg Carvedilol Beta adrenergic  Fatigue  Bronchial Asthma portions of CNS  Hypotension  Severe Bradycardia  Postural Hypertension  Diarrhea  Nausea  Vomiting  Stroke  Bradycardia  May inhibit central  Dizziness  Hypersensitivity to drug Aldomet Methyldopa 250mg vasomotor centers  Depression  Nausea  Vomiting  Diarrhea ↓ Aldosterone secretion  Dizziness  Hypersensitivity to drug Capote Captopril and reduces water &  Headache sodium retention which  Fatigue lowers BP  Hypotension  Diarrhea  Nausea  Vomiting ↓ Aldosterone secretion  Dizziness  Hypersensitivity to drug Enalapril Enam Enalapril and reduces water &  Headache (Vasotec) Maleate sodium retention which  Fatigue lowers BP  Hypotension  Diarrhea  Nausea ACE Inhibitor  Vomiting 1 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade name Generic Name Dosage Action Adverse Contraindications Reaction Anti-Anginals: Calcium Channel Blockers  Relaxes vascular  Dizziness  Hypersensitivity to drug Isodril Isosorbide smooth muscle,  Weakness  Severe Hypotension Dinitrate thereby↓ CO2  Headache  ↑ Intracranial pressure demand  Nausea   Vomiting  Tachycardia  Palpitations  Ankle swelling (edema)  Relaxes vascular  Dizziness  Hypersensitivity to drug GTN Nitroglycerin smooth muscle,  Weakness  Severe Hypotension (glyceryl thereby↓ CO2  Headache  ↑ Intracranial pressure trinitrate) demand  Nausea  Severe Anemia  Vomiting  Inhibits calcium ion  Dizziness  Hypersensitivity to drug Nifedipine Nifedipine 20mg PO entry across cardiac  Headache  Hypotension & smooth muscle  Fatigue  Heart failure cells  Nausea  Decreases  Diarrhea contractility and  Dyspnea oxygen demand  Inhibits calcium ion  Dizziness  Hypersensitivity to drug Norvasc Amlodipine entry across cardiac  Headache  Hypotension & smooth muscle  Fatigue  Heart failure cells  Nausea  Decreases  Sexual difficulty contractility and  Dyspnea oxygen demand 2.5 –  ↓ cardiac oxygen  Fatigue  Bronchial Asthma Propranolol Propranolol 5mg PO demand by blocking  Lethargy  Hepatic or Renal disease OD Hydrochloride catecholamine  Fever induced  Diarrhea  Nausea  Vomiting Cardiac Glycoside  Slow, Steady &  Dizziness  Hypersensitivity to drug Digoxin Digoxin strengthen heartbeat  Headache  Severe pulmonary disease (Digitalis-Fox  Promotes movement  Diarrhea  Hypothyroidism glove plant) of calcium from  Nausea extracellular to  Vomiting intracellular  Fatigue cytoplasm  Strengthen With-hold if pulse myocardial is < 60bpm contraction 2 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Name Dosage Action Adverse reactions Contraindications Anti-Coagulants - To prevent the formation of blood clots Heparin Heparin  Accelerates  Pyrexia  Hypersensitivity to drug Sodium formation of  Hemorrhage  Menses or after child birth antithrobin III-  Pruritus  Hepatic or renal disease Thrombin complex  Urticaria and deactivates  Mild pain thrombin, preventing conversion of Antidote: fibrogen to fibrin. Protamine Heparin with Sulphate warfarin  Heparin is often administered Coumadin Warfarin  Inhibits Vitamin K-  Pyrexia  Hypersensitivity to drug Sodium Dependent activation  Headache  Menses or after child birth of clotting factors II,  Diarrhea  Hepatic or renal disease VII, IX and X,  Anorexia formed in the liver  Nausea  Vomiting  Heparin is often  Hematuria administered with  Hepatitis Antidote: warfarin. This is as Vit K warfarin’s action is delayed. Heparin is then tapered off; as abrupt withdrawal may cause increase coagubility. Clexane Enoxaparin  clexae Injection  Bleeding  Hypersensitivity to drug Sodium contains the active  Pain & irritation  Menses or after child birth ingredient to injection site  Hepatic or renal disease enoxaparin, which is  High Blood Administer SC a type of medicine Potassium level as it absorbs called a low (Hyperkalemia) faster molecular weight  Osteoporosis heparin. It works by inactivating thrombin in the clotting process Diuretics  Loop diuretic  Dizziness  Hypersensitivity to drug Lasix Furosemide  Inhibits Sodium  Headache  Anuria chloride reabsorption  Weakness  Hepatic Cirrhosis from ascending  Diarrhea Loop of Henley  Abdominal pain  Slows the release of  Nausea potassium, therefore  Vomiting potassium must be  Dehydration replaced in the  Hypokalemia system 3 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Name Dosage Action Adverse reactions Contraindications  Distal tubule diuretic  Headache  Hypersensitivity to drug Aldactone Spironolactone  Antagonizes  Drowsiness  Anuria aldosterone in distal  Weakness  Hepatic Cirrhosis tubules, increasing  Hypotension sodium and water  Diarrhea excretion  Abdominal pain  Causes retention of  Nausea potassium and are  Vomiting therefore used as an  Dehydration alternative to giving  Hypokalemia potassium supplements.  Blocks the enzyme  Headache  Hypersensitivity to drug Diamox Acetazolamide carbonic anhydrase,  Diarrhea  Anuria and produces a weak  Drowsiness  Hepatic Cirrhosis diuretic effect that  Vomiting helps to treat  Dehydration glaucoma by  Hyperkalemia decreasing Ocular Pressure Electrolyte & Fluid Replacement  Replaces potassium  Dizziness  Oliguria (↓ urine output) Slow – K Potassium & maintains  Headache  Anuria Chloride potassium level  Weakness  Hyperkalemia  Hypotension  Abdominal Pain  Nausea  Vomiting  Dehydration  Hypokalemia  Replaces potassium  Abdominal Pain  Oliguria (↓ urine output) Kaylixir Potassium & maintains  Nausea  Anuria Gluconate intracellular &  Vomiting  Hyperkalemia extracellular  Diarrhea potassium levels  Stimulates calcium  Headache  Hyperkalemia Rocaltrol Calcitriol absorption from GI  Weakness  Patients using cardiac tract and promotes  Nausea glycosides (Digoxin) movement of  Vomiting calcium from bone  Constipation to blood  Replaces calcium  Bradycardia  Cancer with bone metastases Calcium Calcium and maintains  Arrhythmias  Ventricular fibrillation Chloride; Chloride; calcium levels.  Constipation  Hypercalcemia Indicated for  Nausea  Hypophosphatemia Calcium Calcium Hypocalcemia  Vomiting  Renal Calculi emergency,  Thirst Gluconate Gluconate hyperphosphatemia  Renal Calculi & hyperkalemia  Hypercalcemia 4 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Name Dosage Action Adverse reactions Contraindications Alkalinizers – Fluid & Electrolyte Balance  Restores buffering  Tetany  Metabolic Alkalosis Sodium Sodium capacity of the body  Edema  Respiratory alkalosis Bicarbonate Bicarbonate & neutralizes excess  Flatulence  Hypocalcemia acid.  Hypokalemia  Loss of chloride  Used as an  Hypernatremia  Renal insufficiency emergency drug for  Heart failure cardiac arrest Antacids  Reduces total acid  Headache  Ventricular fibrillation Ca CO3 Calcium load in GI tract  Weakness  Hypercalcemia Carbonate  Elevates gastric pH to  Nausea  Patients using cardiac reduce pepsin activity  Constipation glycosides (digoxin)  Strengthens mucosal  Flatulence barrier  Increases esophageal sphincter tone Antiemetic  May affect neural  Drowsiness  Hypersensitivity to drug Gravol Dimenhydrinate pathway originating  Headache  Seizures in the labyrinth to  Dizziness  inhibit nausea and  Nausea vomiting  Constipation  Urine retention  Stimulates motility  Anxiety  Hypersensitivity to drug Maxolon Metoclopramide of upper GI tract,  Drowsiness  Seizure Hydrochloride Increases lower  Fatigue esophageal sphincter  Diarrhea tones & blocks  Nausea dopamine receptors at the chemoreceptor trigger zone 5 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade name Generic Dosage Action Adverse Reaction Contraindications Name Antibiotics  Inhibits DNA  Headache  Hypersensitivity to drug Flagyl Metronidazole synthesis of  Dizziness  Hepatic disease microorganisms  Nausea  Diarrhea  Inhibits bacterial  Seizures  Hypersensitivity to drug Noroxin Nofloxacin DNA synthesis  Flatulence  Seizure  Dizziness  Pregnancy  Vomiting  Diarrhea  Nausea  Antifungal  Nausea  Hypersensitivity to drug Mycostatin Nystatin  Vomiting  Headache  ↓ bacterial folic acid  Seizures  Porphyria Septra Co-trimoxazole synthesis  Fatigue  Megaloblastic anemia from  Hallucinations folate deficiency  Diarrhea  Nausea  Vomiting  Abdominal pain Maxipime  Inhibits Bacterial cell  Fever  Hypersensitivity to drug Cefepime wall synthesis  Headache  Hypersensitive to penicillin Hydrochloride  Diarrhea  Nausea  Vaginitis  Vomiting  Inhibits bacteria  Dizziness  Hypersensitivity to drug Zithromax Azithromycin protein synthesis  Fatigue  Hypersensitive to  Headache erythromycin  Diarrhea  Nausea  Vomiting  Inhibits bacterial cell  Dizziness  Hypersensitivity to drug Augmentin Amoxicillin wall synthesis  Nausea  Hypersensitive to penicillin (Penicillin  Vomiting  Persons receiving drug)  Diarrhea hemodialysis treatment  Vaginitis  Breast feeding women  Thought to inhibit  Burning & Itching  Hypersensitivity to drug Garamycin Gentamicin protein synthesis, of eyes  Hypersensitive to sulfate usually bactericidal  Hyperemia aminoglycosides (Excess blood in vessels)  Kills bacteria by  Headache  Hypersensitivity to drug Fortum Ceftazidime interfering with the  Diarrhea  Kidney Disease ability of bacteria to  Pyrexia form cell walls.  Nausea  Vomiting 6 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS  Kills bacteria by  Headache  Allergic to penicillin Rocephin Ceftriaxone interfering with the  Rash sodium ability of bacteria to  Itching form cell walls.  Diarrhea  Dizziness  Nausea  Vomiting  Kills bacteria that are  Nausea  Hypersensitivity to drug Cipro, Ciprofloxacin causing an infection  Rash  Kidney Disease Ciproxin  Diarrhea Antidiabetics  Biguanides:  Diarrhea  Hypersensitivity to drug Glucophage Metformin Stimulates the uptake  Nausea  Kidney disease of glucose by the  Vomiting  muscles  Flatulence  Sulphonylureas: Diamicron, increases insulin Daonil (Type secretion II)  ↑ glucose transport  Blurred vision  Allergic to pork Humulin R Isophane across muscle & fat  Dry mouth  Hypoglycemia Insulin cell membrane to  Urticaria Humulin N reduce glucose levels  Pruritus  Helps convert  Dyspnea Humulin 70/30 glucose to glycogen  Triggers amino acid uptake and conversion to protein  Stimulates triglyceride formation and inhibits release of free fatty acids from adipose tissue  Stimulates lipoprotein lipase activity which converts circulating lipoproteins to fatty acids 7 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Name Dosage Action Adverse Contraindication Reaction Anti-Lipemics  Interferes with the  Headache  Hypersensitivity to drug Simlo Simvastatin production of  Nausea  Pregnant & Breastfeeding cholesterol in the  Vomiting women body  Diarrhea Anti-Convulsants  Inhibits activity in  Headache  Hypersensitivity to drug Dilantin Phenytoin the area of the brain  Nausea  Sinus Bradycardia responsible for grand  Vomiting mal seizures  Constipation  May depress CNS  Drowsiness  Hypersensitivity to drug Phenobarbitone Phenobarbitone and ↑ seizure  Bradycardia  Hepatic or Renal (phenobarbital) (phenobarbital) threshold  Vomiting Dysfunction  Respiratory Depression  Apnea  Inhibits activity in  Headache  Hypersensitivity to drug Tegretol Carbamazepine the area of the brain  Nausea  Hepatic dysfunction responsible for  Vomiting grand mal seizures  Constipation Anxiolytic – Used to relief Anxiety or minor tranquilizer  Depresses the CNS  Drowsiness  Hypersensitivity to drug Valium Diazepam  Suppresses the  Headaches  Liver or renal impairment spread of seizure  Bradycardia activity  Hypotension  Indicated for status  Nausea epilepticus, severe  Constipation recurrent seizures, and for patients on stable regiments of antiepileptic drugs who need diazepam intermittently to control bouts of increased seizure activity. 8 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade name Generic Dosage Action Adverse Contraindication Name Reaction Anti-ulcer  Inhibits activity of  Headache  Hypersensitivity to drug Omez Omeprazole gastric parietal cells  Nausea  Hypocalcemia to block formation  Vomiting of gastric acid  Constipation  Reduces gastric acid  Headache  Hypersensitivity to drug Nexium Esomeprazole secretion and  Nausea  Hepatic insufficiency Magnesium decreases gastric  Vomiting  Breastfeeding or pregnant acidity  Diarrhea women  Inhibits proton pump  Dizziness  Hypokalemia Pantecta Pantoprazole activity by binding  Headache  Respiratory Alkalosis to hydrogen  Abdominal Pain potassium adenosine  Diarrhea triphosphate, located  Nausea at secretory surface  Vomiting of gastric parietal  Flatulence cells to suppress gastric acid secretion  Competitively  Headache  Acute porphyria Zantac Ranidine inhibits action of  Malaise Hydrochloride histamine on the H2  Vertigo at receptor sites of  Blurred vision parietal cells,  Jaundice decreasing gastric acid secretion  Prescribed for  Headache  Allergy to prostaglandins Cytotec Misoprostol stomach ulcer,  Abdominal pain  Inflammatory bowel suppresses stomach  Diarrhea disease acid secretion and  Nausea increases gastric  Vomiting mucus and  Hypermenorrhea bicarbonate production.  It may also be used to soften the cervix, inducing contractions to begin labour 9 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Dosage Action Adverse Contraindication Name Reaction Laxative  Produces an osmotic  Abdominal  Low galactose diet Lactulose, Lactulose effect in colon, cramps  Diabetes Mellitus duphala, resulting distention  Belching Lactulax promotes peristalsis  Diarrhea  Flatulence  Gaseous distention  Nausea  Vomiting Analgesic  Inhibit the reuptake of  Dizziness  Hypersensitivity to drug Ultram Tramadol norepinephrine and  Headache  seizure Hydrochloride serotonin  Vertigo  Seizures  Vomiting  Constipation Local Anti-Infective  Inhibits bacterial  SKIN burning  Hypersensitivity to drug Batroban Mupirocin synthesis by  Itching (topical) reversibly and  Stinging rash specifically binding to  Pain Erythema bacterial isoleucyl with topical use transfer – RNA synthase. Corticosteroids Dexamethasone Dexamethasone  ↓ inflammation  Euphoria  GI Ulcer mainly by stabilizing  Insomnia  Renal disease leukocyte lysosomal  Headache  Heart Failure membranes  Heart failure  suppresses bone  Hypertension marrow  Nausea  influences protein fat  Vomiting and carbohydrate metabolism  ↓ inflammation  Vertigo  GI Ulcer Hydrocortone Hydrocortisone mainly by stabilizing  Headaches  Renal Disease leukocyte lysosomal  Paraesthesia  Heart failure membranes  Nausea  suppresses bone  Vomiting marrow  Fatigue  influences protein fat and carbohydrate metabolism Indicated for Asthma 10 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Dosage Action Adverse Contraindication Name Reaction  ↓ inflammation  Euphoria  GI Ulcer Solu-Medrol Methyl- mainly by stabilizing  Insomnia  Renal Disease prednisolone leukocyte lysosomal  Heart failure  Heart failure sodium membranes  Hypertension succinate  suppresses immune  Nausea response  Vomiting  influences protein fat  ↑ urine glucose & and carbohydrate calcium levels metabolism Emergency drug for shock  ↓inflammation mainly  Vertigo  GI Ulcer Prednisolone Prednisolone by stabilizing  Headache  Renal Disease leukocyte lysosomal  Nausea  Heart failure membranes  Vomiting  suppresses bone  Fatigue marrow  Paraesthesia  influences protein fat and carbohydrate metabolism Indicated for Asthma Anti-Neoplastics  Used as an adjunct  Stoke  Deep Vein thrombosis Tamoxifen Tamoxifen treatment in breast  Confusion  Pulmonary embolism citrate cancer  Headache  To reduce breast  Weakness cancer occurrence in  Nausea high risk women  Vomiting  Diarrhea Blocks the effects of  Uterine Sarcoma estrogen in breast  Pulmonary tissue Embolism Immunomodulators  Mimics effects of  Asthenia  Breast feeding women Eprex Epotin alfa erythropoietin  Dizziness (erythropoietin)  Functions as a growth  Fatigue factor and as a  Headache differentiating factor,  Seizures enhancing RBC  Pharyngitis production  Constipation  Pyrexia 11 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Dosage Action Adverse Contraindications Name Reaction Ophthalmic Anti-Infective Giloxan Ciprofloxacin  Inhibits bacterial  Local burning or  Hypersensitivity to drug (ophthalmic Hydrochloride DNA gyrase an discomfort  Use cautiously in breast ointment & enzyme needed for  Conjunctival feeding women as drug ophthalmic bacterial replication hyperemia appears in breast milk solution)  Used for corneal ulcer  Itching and bacterial  Bad or bitter taste conjunctivitis in mouth Ophthalmic Anti-Inflammatory  Suppressed Edema,  Cataracts  Acute superficial herpes Pred Forte Prednisolone fibrin deposition,  Corneal ulcer simplex Acetate capillary dilation,  Discharge  Fungal eye disease (suspension) leucocyte migration, increased capillary intraocular proliferation and pressure collagen deposition  Visual field defects used for allergic and inflammatory conditions of the eye Miotic – Pupil Contraction  A cholinergic that  Hypertension  Acute cardiac failure Pilocarpine Pilocarpine causes contraction of  Blurred vision  Bronchial asthma Hydrochloride iris sphincter muscles,  Diarrhea  Peptic Ulcer resulting in miosis and  Nausea produces ciliary  Vomiting spasm, deepening of  Pulmonary edema the anterior chamber and vasodilation of conjunctival vessel of the outflow tract Mydriatic  Dilates pupil of the  Confusion  Hypersensitivity to drug Atropine Atropine sulfate eye  Headache  Blurred vision  Reduces production  Headache  Hypersensitivity to drug Mydriacyl Tropicamide of aqueous humor by  Hypertension unknown  Tachycardia mechanisms.  Dysrhythmias  Used for ocular  Burning & hypertension; stinging of the eye Chronic open-angle glaucoma 12 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Dosage Actions Adverse Contraindications name Reaction  Dilates the pupil by  Brow ache  Angle closure glaucoma Mydfrin Phenylephrine contraction dilator  Headache Hydrochloride muscle  Allergic Conjunctivitis  Blurred Vision Bronchodilators  Relaxes bronchial  Drowsiness  General Anesthesia Epinephrine Epinephrine smooth muscle by  Headache  Cardiovascular Disease (Adrenaline) (Adrenaline stimulating beta II  Nervousness receptors and alpha  Cerebral & beta receptors in Hemorrhage the SNS  Palpitations  Ventricular Fibrillation  Shock  Nausea  Vomiting  Dyspnea  Xanthine  Drowsiness  Hypersensitivity to drug Aminophylline Aminophylline bronchodilator -  Headache  General Anesthesia relaxes bronchial  Nervousness  Cardiovascular disease smooth muscles  Palpitations  Ventricular Fibrillation  Shock  Nausea  Vomiting  Relaxes bronchial  Headache  Hypersensitivity to drug Isuprel HcL Isoproterenol smooth muscles by  Dizziness  General Anesthesia (Refrigerate) Hydrochloride stimulating beta II  Tachycardia  Cardiovascular disease receptors, as a  Angina cardiac stimulant  Rapid ↑ and ↓ in acts on beta I BP receptors in the heart  Nausea  Vomiting  Diaphoresis (Sweating)  Anticholinergic:  Bronchitis  Hypersensitivity to drug Atrovent Ipratropium Inhibits vaguely  URTI  General Anesthesia bromide mediate reflexes by  Nervousness  Cardiovascular disease antagonizing  Dizziness acetylcholine at  Headache muscarinic receptors  Dry mouth on bronchial smooth  Throat irritation muscle, thereby ↓  Cough bronchial muscle  Heat palpitations spasms (during an  Nausea asthma attack) 13 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Name Dosage Action Adverse Reaction Contraindications  Prophylactic action  Coughing  Hypersensitivity to drug Intal Cromolyn prevents the release  Sneezing  General Anesthesia Sodium of chemical  Nasal congestion  Cardiovascular disease mediators of  Throat irritation anaphylaxis (slow  Nausea reacting substances  Wheezing of Anaphylaxis – histamine, prostaglandin, bradykinin) and used to prevent asthma attacks  Stimulates beta II  Agitation  Hypersensitivity to drug Ventolin Albuterol receptors relaxing  Diarrhea  General Anesthesia constricted muscles  Dizziness  Cardiovascular disease of the lungs bronchi  Headache  Indigestion  Nausea  Muscle Cramps  Nose bleeds  Tinnitus  Sleeplessness  Vomiting  Decrease  Cough  Hypersensitivity to drug Beclovent; Beclomethason inflammation by  Tachycardia  General Anesthesia Beconase e dipropionate decreasing the  Fluid retention  Cardiovascular disease number and activity  Hives of inflammatory  Wheezing cells, inhibiting  Rash bronchoconstriction mechanisms producing direct smooth muscle relaxation, and ↓ airway hyper- responsiveness. Doesn’t provide immediate relief 14 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Name Dosage Action Adverse Reaction Contraindications Neuromuscular Blockers  Binds with a high  Arrhythmias  Hypersensitivity to drug Anectine Succinylcholine affinity to  Bradycardia (Refrigerate) Chloride cholinergic  Cardia arrest receptors, prolonging  Apnea depolarization of the  Bronchoconstrictio motor end plate and n ultimately producing  Prolonged muscle paralysis Respirator depression  Anaphylaxis  Malignant hyperthermia  Rhabdomyolysis with acute renal failure  May block central  Confusion  Hypersensitivity to drug Cogentin Bentropine cholinergic  Memory  Cardiovascular disease Mesylate receptors, helping impairment balance cholinergic  Hallucinations activity in the basal  Tachycardia ganglia.  Constipation  Nausea Cogentin is given to  Vomiting treat side effects of  Paralytic ileus above mentioned  Urine retention antipsychotic drugs Antiparkinsons  May decarboxylated  Orthostatic  Hypersensitivity to drug Larodopa Levodopa to dopamine, hypertension  Severe cardiovascular countering the  Phlebitis disease depletion of striatal  Anorexia dopamine in  Nausea extrapyramidal  Vomiting centers; this  Urine retention depletion is thought to produce parkinsonism 15 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Name Dosage Action Adverse Reaction Contraindications Adrenergic (sympathominetics)  Stimulates heart beat  Headache  Hypersensitivity to drug Dobutrex Dobutamine 1 receptor to increase  Hypertension Hydrochloride myocardial  Nausea contractility and  Vomiting stroke volume  Dyspnea  Used to ↑ cardia output in short term treatment of cardiac decompensation cause by depressed contractility  Stimulates  Headache  Hypersensitivity to drug Dopamine Dopamine dopaminergic and  Anxiety  Occlusive vascular disease (Intropin) Hydrochloride alpha & beta  Hypotension  Ventricular Fibrillation receptors of the SNS  Ventricular resulting in positive Arrhythmia inotropic effect and ↑  Nausea cardiac output.  Vomiting  Treats hemodynamic  Dypsnea imbalances and shock  To improve perfusion to vital organs  To correct hypotension Opioids  Binds with opiate  Dizziness  Hypersensitivity to drug Morphine Morphine receptors in CNS,  Seizures  Opioid addiction Sulphate alternating  Bradycardia perception of and  Cardiac Arrest Morphine emotional response  Shock Hydrochloride to pain  Hypotension  Constipation  Nausea  Vomiting  Diaphoresis  Binds to and  Confusion  Pethidine Demerol depresses opiate  Sedation meperidine receptors in spinal  Headache cord and CNS,  Hypotension altering perception  Cardiac Arrest and of response to  Bradycardia pain  Shock  Nausea  Respiratory Depression  Vomiting  Constipation 16 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Name Dosage Action Adverse Reaction Contraindications Opioid Antagonist  May displace opioid  Seizures  Hypersensitivity to drug Narcan Naloxone analgesics from their  Ventricular  Cardiac Irritability Hydrochloride receptors fibrillation  Opioid addiction (competitive  Tachycardia antagonism).  Nausea  Vomiting Known to cause opioid  Pulmonary edema induced respiratory  Diaphoresis depression Antidepressants  selective serotonin  Nervousness  Hypersensitivity to drug Prozac Fluoxetine reuptake inhibitors  Headache  High risk for suicide Hydrochloride (SSRI)  Insomnia antidepressant  Nausea  used to treat major  Diarrhea depressive disorder,  Anorexia bulimia nervosa (an  Dyspepsia eating disorder)  Constipation obsessive- compulsive disorder, and panic disorder Anti-psychotics  A piperidine that  Parkinsons – like  Hypersensitivity to drug Thorazine Chloropromazine may block condition (dry  Cardiovascular disease Hydrochloride postsynaptic mouth, blurred dopamine receptors vision, postural in the brain. hypotension, Dopamine is a dizziness & neurotransmitter of Nausea nervous impulses  A piperidine that  Parkinsons – like  Hypersensitivity to drug Haldol Haloperidol may block condition (dry  Cardiovascular disease postsynaptic mouth, blurred dopamine receptors vision, postural in the brain. hypotension, dizziness & Nausea  A piperidine that  Parkinsons – like  Hypersensitivity to drug Stelazine Trifluoperazine may block condition (dry  Cardiovascular disease Hydrochloride postsynaptic mouth, blurred dopamine receptors vision, postural in the brain. hypotension, dizziness & Nausea 17 MEDICATIONS – DOSAGE, USAGE, SIDE EFFECTS & CONTRAINDICATIONS Trade Name Generic Name Dosage Action Adverse Reaction Contraindications Anti-Tuberculotics  Antibiotic,  Peripheral  Hypersensitivity to drug Isoniazid Isoniazid (INH bactericidal. May neuropathy isonicotinic inhibit cell wall  Seizures acid hydrazide) biosynthesis by  Nausea interfering with lipid  Vomiting & DNA synthesis.  Aplastic anemia  Jaundice  Agranulocytosis  Antibiotic,  Headache  Hypersensitivity to drug Rifampin Rifampin bactericidal. Inhibits  Dizziness  Liver disease (rifampicin) DNA - dependent  Vomiting RNA polymerase  Diarrhea which impairs RNA  Anorexia synthesis  Flatulence  Hyperuricaemia  Antibiotic; inhibits  Headache  Hypersensitivity to drug Mycobutin Rifabutin DNA – dependent  Fever  Neutropenia RNA polymerase in  Dyspepsia  Thrombocytopenia susceptible bacteria,  Flatulence blocking bacteria  Diarrhea protein synthesis  Nausea  Vomiting  Myalgia (muscle pain)   Headache  Hypersensitivity to drug Priftin Rifapentine  Hypertension  Liver disease  Anorexia  Dizziness  Nausea  Vomiting  Dyspepsia  Diarrhea  Pyuria  Proteinuria 18

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