Medical Microbiology MCQs PDF

Medical Microbiology - Multiple Choice Questions (MCQs) 1. What is the causative agent of syphilis? a) Borrelia burgdorferi b) Treponema pallidum c) Leptospira interrogans d) Rickettsia prowazekii 2. Which stage of syphilis is characterized by painless ulcers? a) Primary stage b) Secon...

Medical Microbiology - Multiple Choice Questions (MCQs) 1. What is the causative agent of syphilis? a) Borrelia burgdorferi b) Treponema pallidum c) Leptospira interrogans d) Rickettsia prowazekii 2. Which stage of syphilis is characterized by painless ulcers? a) Primary stage b) Secondary stage c) Latent stage d) Tertiary stage 3. Which serological test detects 'reagin' antibody? a) VDRL test b) FTA-ABS test c) PCR d) TPHA test 4. Which diagnostic technique is used for T. pallidum in the primary stage? a) ELISA b) Dark-field microscopy c) Rapid plasma reagin (RPR) d) Agglutination test 5. What is the primary treatment for syphilis? a) Tetracycline b) Penicillin G c) Doxycycline  d) Erythromycin 6. What distinguishes Bejel from Pinta? a) Bejel is sexually transmitted b) Bejel involves deeper tissue damage c) Pinta is caused by a virus d) Pinta affects the bones 7. What organism causes Lyme disease? a) Treponema carateum b) Borrelia burgdorferi c) Leptospira interrogans d) Treponema pertenue 8. What is a characteristic symptom of the early stage of Lyme disease? a) Joint pain b) Circular red rash c) Hair loss d) Enlarged lymph nodes 9. How is B. recurrentis transmitted to humans? a) Tick bites b) Louse bites c) Mosquito bites d) Inhalation of spores 10. What stain is used for identifying Borrelia species? a) Giemsa stain b) Gram stain c) Acid-fast stain d) Silver stain 11. What is the primary reservoir for Coxiella burnetii? a) Humans b) Cattle c) Birds d) Arthropods 12. What is the primary symptom of Q fever? a) Rash b) Myocarditis c) Atypical pneumonia d) Enlarged lymph nodes 13. What antibiotic is effective against all Rickettsial diseases? a) Penicillin b) Chloramphenicol c) Amoxicillin d) Metronidazole 14. Which Rickettsial disease has a centripetal rash pattern? a) Epidemic typhus b) Rocky Mountain spotted fever c) Q fever d) Murine typhus 15. What is the vector for epidemic typhus? a) Fleas b) Ticks c) Lice d) Mites 16. What distinguishes murine typhus from epidemic typhus?  a) Murine typhus causes a centripetal rash b) Murine typhus is transmitted by lice c) Murine typhus resolves without treatment d) Murine typhus causes myocarditis 17. What feature allows Coxiella to survive in harsh conditions? a) Capsule formation b) Intracellular survival in phagolysosomes c) Rapid replication d) Ability to form spores 18. Which test confirms Rickettsial infections? a) PCR b) Gram stain c) Silver stain d) Agglutination test 19. What is the most common prevention for tick-borne diseases? a) Antibiotic prophylaxis b) Vaccination c) Avoidance of tick habitats d) Wearing gloves 20. What is the causative agent of Rocky Mountain Spotted Fever? a) Rickettsia rickettsii b) Rickettsia prowazekii c) Coxiella burnetii d) Rickettsia typhi 21. Which form of Chlamydia is metabolically active? a) Elementary body  b) Reticulate body c) Spore d) Vegetative cell 22. What is the main transmission method for C. psittaci? a) Tick bites b) Louse bites c) Inhalation of infected bird droppings d) Contact with infected urine 23. What is a major complication of trachoma? a) Blindness b) Pneumonia c) Skin rash d) Joint pain 24. Which antibiotic is preferred for treating Chlamydia infections? a) Penicillin b) Tetracycline c) Metronidazole d) Amoxicillin 25. How does Mycoplasma differ from other bacteria? a) Presence of capsule b) Lack of cell wall c) Rapid growth d) Gram-positive nature 26. What is the main virulence factor of Mycoplasma? a) Capsule formation b) Hydrogen peroxide production  c) Lipopolysaccharide layer d) Rapid replication 27. What is the hallmark symptom of actinomycosis? a) Sulfur granules in lesions b) Pulmonary abscesses c) Joint pain d) Skin rash 28. Which organism causes Madura foot? a) Actinomyces israelii b) Nocardia asteroides c) Mycobacterium leprae d) Treponema pertenue 29. How is Nocardia most commonly transmitted? a) Direct contact b) Inhalation c) Tick bites d) Blood transfusion 30. What diagnostic test is used for actinomycosis? a) ELISA b) Gram stain c) PCR d) Silver stain