Male Reproductive Histology PDF

Practical Male reproductive system Histology By Dr.Diena Idris Male Genital System Two testes..formation of spermatozoa & synthesis, release and storage of testosterone Genital ducts...

Practical Male reproductive system Histology By Dr.Diena Idris Male Genital System Two testes..formation of spermatozoa & synthesis, release and storage of testosterone Genital ducts Associated glands..formation of noncellular portion of semen Paired seminal vesicles Single prostate glands Bulbourethral (Cowper) glands Penis...delivery of semen to female reproductive system  Testes Paired oval organs, located in the scrotum (approx 4x3x3cm) Tunica albuginea (irregular dense connective tissue) surrounds each testis Tunica vasculosa (highly vascular loose connective tissue) located immediately deep to TA forms the vascular capsule. Testes The posterior aspect of TA is thickened to form mediastinum testis. The connective tissue septa radiate from MT to subdivide each testis into approx 250 pyramid shaped lobuli testis. Each lobule has 1-4 blindly ending seminiferous tubules Richly vascularized and innervated loose connective tissue derived from TV surrounds STs. Interstitial cells of Leydig make groups within this CT. Each seminephrous tubule is lined by spermatognia and spermatogenic epithelium and sertoli cells  Part of the wall of a seminiferous tubule. Several cells of the spermatogenic lineage are present: a spermatogonium, primary spermatocytes, and young and late spermatids. The approximate limits of a Sertoli cell holding several spermatids are delineated. H&E stain. High magnification.  Spermatocytes and spermatids in the epithelium of a seminiferous tubule. The tubule is covered by myoid cells.. Leydig cells Epithelium of seminiferous tubules surrounded by myoid cells. The spaces between the tubules contain connective tissue, blood and lymphatic vessels, and interstitial cells. Secretes testosterone in response to Luetenizing hormome secreted by anterior pituitary gland While the spermatogonia develop under the influence of FSH.Follicle stimulating hormone.  Extra testicular genital ducts Epididymis Ductus deferens Ductus ejaculatorius Epididymis Highly coiled ductus epididymidis, sectioned several times. Its wall is made of a pseudostratified columnar epithelium surrounded by connective tissue and smooth muscle. Inset: Higher magnification of the epithelial cells with their long microvilli (stereocilia).  Ductus deferens (Vas deferens) Each DF is a thick walled muscular tube with a small irregular lumen that conveys the spermatozoa from the tail of the epididimis to the ejaculatory duct. Mucosa formed by pseudostratified columnar epithelium (principal cells are shorter) with stereocilia and a lamina propria. Thick outer wall is formed of smooth muscle (three layers:inner outer longitudunal middle circular) and collagen fibers (blue). SML isinvested by a thin layer of fibroelastic connective tissue Accessory genital glands Paired seminal vesicle Single prostate gland Paired bulbourethral glands Seminal vesicles About 15 cm long highly tubular structures located between post aspect of the neck of the bladder and the prostate gland; and join the ampulla of the ductus deferens just above the prostate gland Its mucosa is highly convoluted forming labyrinth-like cul-de-sacs that are observed to open into a central lumen. Lumen is lined by a pseudustartified columnar epithelium (short basal cells and low columnar) Each columnar cell cell-with numerous short microvilli and a single flagellum Subepithelial fibroelastic CT is surrounded by inner circular outer longitudinal smooth muscle coat SM is surrounded by fibroelastic CT again This gland produces a viscose yellow fructose rich seminal fluid that makes 70% of the volume of the semen. It is the source of the enery for the spermatozoa. The characteristic pale yellow colour of semen is due to the lipochrome pigment released by seminal vesicles Seminal vesicles Tortuous tubular gland with a much- folded mucosa gives the impression that the gland consists of many tubules. Prostate Mucosal glands are closest to the urethra and thus are the shortest of the glands Submucosal glands are peripheral to the mucosal glands and are consequently larger than the mucosal glands. Largest and most numerous of the glands are the peripheralmost main glands, which compose the bulk of the prostate. Lumina of the tubuloalveolar glands frequently house round to oval prostatic concretions (corpora amylacea), composed of calcified glycoproteins, whose numbers increase with a person’s age. Prostate Distribution of its glands in 3 zones. The gland ducts open into the urethra. Prostate Section of the central region of the prostate showing the prostatic urethra and tubuloalveolar glands surrounded by connective tissue and smooth muscle. Prostate Components of prostate gland are lined by a simple to pseudustratified to columnar epihelium; surrounded by connective tissue and smooth muscle. Bulbourethral (Cowper’s) glands Paired small (3-5 mm diam) glands located at the root of penis, just just at the beginning of membranous urethra Capsule contains fibroblasts, smooth and skeletal muscle cells (sk muscle derived from the muscles of the urogenital diaphragm) Capsule sends septa dividing each gland into lobules Epith of these compound tubuloalveolar glands varies from simple cuboidal to simple columnar The secretion is a thick slippery fluid that lubricate the lumen of the urethra  Penis Is composed of three columns of erectile tissue, each enclosed by its own dense, fibrous connective tissue capsule, the tunica albuginea. Two of the columns of erectile tissue, the corpora cavernosa, are positioned dorsally; their tunicae albugineae are discontinuous in places, permitting communication between their erectile tissues. Third column of erectile tissue, the corpus spongiosum, is positioned ventrally. Because the CS houses the penile portion of the urethra, it is also called the corpus cavernosum urethrae. CS ends distally in an enlarged, bulbous portion, the glans penis (head of the penis). The tip of the glans penis is pierced by the end of the urethra as a vertical slit. Penis Thankyou!