Lithium Carbonate Medication Guide PDF

Toxicity grades: Pt Teaching Grade1 : (1.5-2.5 mEq/L). ¤Take this drug exactly as prescribed, after S/S: Nausea ,Vomiting, Tremors, Hyperreflexia, meals or with food or milk. Swallow extended...

Toxicity grades: Pt Teaching Grade1 : (1.5-2.5 mEq/L). ¤Take this drug exactly as prescribed, after S/S: Nausea ,Vomiting, Tremors, Hyperreflexia, meals or with food or milk. Swallow extended- Ataxia, Muscular weakness. or controlled-release tablets whole; do not Treatment: Hydration Q4-6 hours, Kayexalate. chew or crush. Grade2 : (2.5-3.5mEq/L ). ¤Eat a normal diet with normal salt intake; S/S: Hypertonia, Hypotension, Rigidity, Stupor. maintain adequate fluid intake (at least 2.5 Treatment: Hydration, Kayexalate, dialysis. Lithium quarts/day). ¤Arrange for frequent checkups, including blood tests. Keep all appointments for Grade3:>3.5 mEq/L. S/S: Coma and Seizure. Treatment: Hemodialysis. Carbonate checkups to get the most benefits with the least toxicity. ¤Discontinue drug, and notify your health care Contraindications 1. Hypersensitivity provider if toxicity occurs—diarrhea, vomiting, 2. Cardiac &renal disease ataxia, tremor, drowsiness, lack of coordination 3. Dehydration &sodium depletion or muscular weakness. 4. Brain damage ¤You may experience these side effects: 5. Pregnancy and lactation Drowsiness, dizziness (avoid driving or performing tasks that require alertness); GI upset (eat frequent small meals); mild thirst, BLACK BOX greater than usual urine volume, fine hand tremor (may persist throughout therapy; notify WARNING: your health care provider if severe). Report diarrhea or fever. Monitor clinical status closely, especially ¤drug-drug interactions: during initial stages of therapy twice per ACE Inhibitors, Thiazide diuretics, week and for maintenance dose once Carbazepine,NSAIDs, methyldopa,fluoxetine monthly ; monitor for therapeutic serum ¤drug-food interactions: levels of 0.6–1.2 mEq/L; toxicity is closely caffeine as a natural diuretics, sodium should related to serum levels. normal intake  Side Effect: Dosing: Classification ¤Initial dose: Often begins around 600- Leukocytosis & 900 mg/day, typically split into 2-3 doses Action ¤Maintenance dose: Generally ranges ¤Anti manic drug Increase thirst,urine, weight from 900 to 1,200 mg/day, divided into 2- 3 doses ¤ Mechanism of action: ¤Acute Mania or Severe Cases: the dose Tremor, Tinnig hair Unknown Mechanism, but it’s thought to be may start higher, usually around 1,800 to working in CNS and alters chemical transmitter 2,400 mg/day by decrease dopamine and norepinephrine Target blood levels: It's known as release and increase serotonin synthesis Hypothyroidism, hypotension narrow therapeutic range so the normal range for lithium is typically between 0.6 and 1.2 mEq/L Indication: Impaired memories Toxicity: It's used to treat Upset stomach 1. Bipolar disease The toxicity occurs when the lithium level 2. Mania and hypomania reaches above 1.5mEq/L 3. Recurrent and sever depression 5. Used to treat symptoms of mania (high Medications interactions Factor ⬆️toxicity: level of energy, feeling extremely happy 1-Fluid loss and dehydration ,not sleeping or get few hours of sleep, 2-Hyponatremia euphoria, hyper activity, risk taking 3-Decrease renal function Skin issues behavior, being talkative) 4-NSAIDS 6. Schezoaffective 5-Thiazide diuretics 6-ACE inhibitors 7-Antipsychotics 8-Fluoxetine