Meiosis and Sexual Life Cycles PDF

Chapter 13 Meiosis and Sexual Life Cycles Lecture Presentations by Nicole Tunbridge and © 2021 Pearson Education, Inc....

Chapter 13 Meiosis and Sexual Life Cycles Lecture Presentations by Nicole Tunbridge and © 2021 Pearson Education, Inc. Kathleen Fitzpatrick Figure 13.1 © 2021 Pearson Education, Inc. Figure 13.1 © 2021 Pearson Education, Inc. CONCEPT 13.1: Offspring acquire genes from parents by inheriting chromosomes The transmission of traits from one generation to the next is called inheritance, or heredity Sons and daughters are not identical copies of either parent or of their siblings Along with inherited similarity, there is variation The study of heredity and inherited variation is called genetics © 2021 Pearson Education, Inc. Inheritance of Genes Genes are the units of heredity and are made up of segments of DNA Genes are passed to the next generation via reproductive cells called gametes (sperm and eggs) Most DNA is packaged into chromosomes Humans have 46 chromosomes in the nuclei of their somatic cells—all cells of the body except gametes and their precursors A gene’s specific position along a chromosome is called its locus © 2021 Pearson Education, Inc. Comparison of Asexual and Sexual Reproduction In asexual reproduction, a single individual passes all of its genes to its offspring without the fusion of gametes A clone is an individual or group of genetically identical individuals from the same parent In sexual reproduction, two parents give rise to offspring that have unique combinations of genes inherited from the two parents © 2021 Pearson Education, Inc. Figure 13.2 © 2021 Pearson Education, Inc. Video: Hydra Budding © 2021 Pearson Education, Inc. CONCEPT 13.2: Fertilization and meiosis alternate in sexual life cycles A life cycle is the generation-to-generation sequence of stages in the reproductive history of an organism The behavior of chromosomes is related to the human lifecycle and other types of sexual life cycles © 2021 Pearson Education, Inc. Sets of Chromosomes in Human Cells Human somatic cells have 23 pairs of chromosomes A karyotype is an ordered display of the pairs of chromosomes from a cell The two chromosomes in each pair are called homologous chromosomes, or homologs Chromosomes in a homologous pair have the same length, centromere position, and staining pattern They also carry genes controlling the same inherited characters © 2021 Pearson Education, Inc. Figure 13.3 © 2021 Pearson Education, Inc.  The sex chromosomes, which determine the sex of the individual, are called X and Y Human females have a homologous pair of X chromosomes (XX) Human males have one X and one Y chromosome The remaining 22 pairs of chromosomes are called autosomes © 2021 Pearson Education, Inc.  Each pair of homologous chromosomes includes one chromosome from each parent The 46 chromosomes in a human somatic cell are two sets of 23: one from the mother and one from the father A diploid cell (2n) has two sets of chromosomes For humans, the diploid number is 46 (2n = 46) © 2021 Pearson Education, Inc.  In a cell in which DNA synthesis has occurred, each chromosome is replicated Each replicated chromosome consists of two identical sister chromatids © 2021 Pearson Education, Inc.  A gamete (sperm or egg) contains a single set of chromosomes and is thus a haploid cell (n) For humans, the haploid number is 23 (n = 23) Each set of 23 consists of 22 autosomes and a single sex chromosome In an unfertilized egg (ovum), the sex chromosome is X In a sperm cell, the sex chromosome may be either X or Y © 2021 Pearson Education, Inc. Figure 13.4 © 2021 Pearson Education, Inc. Behavior of Chromosome Sets in the Human Life Cycle Fertilization is the union of gametes (the sperm and the egg) The fertilized egg is called a zygote and has one set of chromosomes from each parent The zygote produces somatic cells by mitosis and develops into an adult © 2021 Pearson Education, Inc. Figure 13.5 © 2021 Pearson Education, Inc.  The ovaries and testes produce haploid gametes Gametes are the only type of human cells produced by meiosis, rather than by mitosis Meiosis results in one set of chromosomes in each gamete Fertilization and meiosis alternate in sexual life cycles to maintain chromosome number © 2021 Pearson Education, Inc. The Variety of Sexual Life Cycles The alternation of meiosis and fertilization is common to all organisms that reproduce sexually The three main types of sexual life cycles differ in the timing of meiosis and fertilization © 2021 Pearson Education, Inc. Figure 13.6 © 2021 Pearson Education, Inc.  Gametes are the only haploid cells in most animals They are produced by meiosis and undergo no further cell division before fertilization Gametes fuse to form a diploid zygote that divides by mitosis to develop into a multicellular organism © 2021 Pearson Education, Inc. Figure 13.6a © 2021 Pearson Education, Inc.  Plants and some algae exhibit an alternation of generations This life cycle includes both a diploid and haploid multicellular stage The diploid organism, called the sporophyte, makes haploid spores by meiosis © 2021 Pearson Education, Inc.  Each spore grows by mitosis into a haploid organism called a gametophyte A gametophyte makes haploid gametes by mitosis Fertilization of gametes results in a diploid sporophyte © 2021 Pearson Education, Inc. Figure 13.6b © 2021 Pearson Education, Inc.  In most fungi and some protists, the only diploid stage is the single-celled zygote; there is no multicellular diploid stage The zygote produces haploid cells by meiosis Each haploid cell grows by mitosis into a haploid multicellular organism The haploid adult produces gametes by mitosis © 2021 Pearson Education, Inc. Figure 13.6c © 2021 Pearson Education, Inc.  Depending on the type of life cycle, either haploid or diploid cells can divide by mitosis However, only diploid cells can undergo meiosis In all three life cycles, the halving and doubling of chromosomes contribute to genetic variation in offspring © 2021 Pearson Education, Inc. CONCEPT 13.3: Meiosis reduces the number of chromosome sets from diploid to haploid Like mitosis, meiosis is preceded by the replication of chromosomes Meiosis takes place in two consecutive cell divisions, called meiosis I and meiosis II The two cell divisions result in four daughter cells, rather than the two daughter cells in mitosis Each daughter cell has only half as many chromosomes as the parent cell © 2021 Pearson Education, Inc. Figure 13.7 © 2021 Pearson Education, Inc. The Stages of Meiosis Chromosomes duplicate before meiosis The resulting sister chromatids are closely associated along their lengths This is called sister chromatid cohesion The chromatids are sorted into four haploid daughter cells © 2021 Pearson Education, Inc.  Division in meiosis I occurs in four phases: – Prophase I – Metaphase I – Anaphase I – Telophase I and cytokinesis © 2021 Pearson Education, Inc.  Prophase I In early prophase I, each chromosome pairs with its homolog and crossing over occurs X-shaped regions called chiasmata are sites of crossovers © 2021 Pearson Education, Inc.  Metaphase I In metaphase I, pairs of homologs line up at the metaphase plate, with one chromosome facing each pole Microtubules from one pole are attached to the kinetochore of one chromosome of each pair Microtubules from the other pole are attached to the kinetochore of the other chromosome © 2021 Pearson Education, Inc.  Anaphase I In anaphase I, pairs of homologous chromosomes separate One chromosome of each pair moves toward opposite poles, guided by the spindle apparatus Sister chromatids remain attached at the centromere and move as one unit toward the pole © 2021 Pearson Education, Inc.  Telophase I and Cytokinesis In the beginning of telophase I, each half of the cell has a haploid set of duplicated chromosomes Each chromosome still consists of two sister chromatids Cytokinesis usually occurs simultaneously, forming two haploid daughter cells © 2021 Pearson Education, Inc.  In animal cells, a cleavage furrow forms; in plant cells, a cell plate forms No chromosome replication occurs between the end of meiosis I and the beginning of meiosis II because the chromosomes are already replicated © 2021 Pearson Education, Inc. Figure 13.8a © 2021 Pearson Education, Inc.  Division in meiosis II also occurs in four phases: – prophase II – metaphase II – anaphase II – telophase II and cytokinesis Meiosis II is very similar to mitosis © 2021 Pearson Education, Inc.  Prophase II In prophase II, a spindle apparatus forms In late prophase II, chromosomes (each still composed of two chromatids) move toward the metaphase plate © 2021 Pearson Education, Inc.  Metaphase II In metaphase II, the sister chromatids are arranged at the metaphase plate Because of crossing over in meiosis I, the two sister chromatids of each chromosome are no longer genetically identical The kinetochores of sister chromatids attach to microtubules extending from opposite poles © 2021 Pearson Education, Inc.  Anaphase II In anaphase II, the sister chromatids separate The sister chromatids of each chromosome now move as two newly individual chromosomes toward opposite poles © 2021 Pearson Education, Inc.  Telophase II and Cytokinesis In telophase II, the chromosomes arrive at opposite poles Nuclei form, and the chromosomes begin decondensing © 2021 Pearson Education, Inc.  Cytokinesis separates the cytoplasm At the end of meiosis, there are four daughter cells, each with a haploid set of unreplicated chromosomes Each daughter cell is genetically distinct from the others and from the parent cell © 2021 Pearson Education, Inc. Figure 13.8b © 2021 Pearson Education, Inc. BioFlix® Animation: Meiosis © 2021 Pearson Education, Inc. Video: Meiosis I in Sperm Formation © 2021 Pearson Education, Inc. Crossing Over and Synapsis During Prophase I After interphase, the sister chromatids are held together by proteins called cohesins The nonsister chromatids are broken at precisely matching points A zipper-like structure called the synaptonemal complex holds the homologs together tightly During synapsis, DNA breaks are repaired, joining DNA from one nonsister chromatid to the corresponding segment of another © 2021 Pearson Education, Inc. Figure 13.9 © 2021 Pearson Education, Inc. A Comparison of Mitosis and Meiosis Mitosis conserves the number of chromosome sets, producing two cells that are genetically identical to the parent cell Meiosis reduces the number of chromosomes sets from two (diploid) to one (haploid), producing four cells that differ genetically from each other and from the parent cell © 2021 Pearson Education, Inc.  Three events are unique to meiosis, and all three occur in meiosis I – 1. Synapsis and crossing over in prophase I: Homologous chromosomes physically connect and exchange genetic information – 2. Alignment of homologous pairs at the metaphase plate – 3. Separation of homologs during anaphase I © 2021 Pearson Education, Inc. Figure 13.10 © 2021 Pearson Education, Inc.  Sister chromatid cohesion allows sister chromatids to stay together through meiosis I In mitosis, cohesins are cleaved at the end of metaphase In meiosis, cohesins are cleaved along the chromosome arms in anaphase I (separation of homologs) and at the centromeres in anaphase II (separation of sister chromatids) © 2021 Pearson Education, Inc. CONCEPT 13.4: Genetic variation produced in sexual life cycles contributes to evolution Mutations (changes in an organism’s DNA) are the original source of genetic diversity Mutations create different versions of genes called alleles Reshuffling of alleles during sexual reproduction produces genetic variation © 2021 Pearson Education, Inc. Origins of Genetic Variation Among Offspring The behavior of chromosomes during meiosis and fertilization is responsible for most of the variation that arises in each generation Three mechanisms contribute to genetic variation: – Independent assortment of chromosomes – Crossing over – Random fertilization © 2021 Pearson Education, Inc. Independent Assortment of Chromosomes Homologous pairs of chromosomes orient randomly at metaphase I of meiosis In independent assortment, each pair of chromosomes sorts maternal and paternal homologs into daughter cells independently of the other pairs © 2021 Pearson Education, Inc.  The number of combinations possible when chromosomes assort independently into gametes is 2n, where n is the haploid number For humans (n = 23), there are more than 8 million (223) possible combinations of chromosomes © 2021 Pearson Education, Inc. Figure 13.11 © 2021 Pearson Education, Inc. Crossing Over Crossing over produces recombinant chromosomes, which combine DNA inherited from each parent Crossing over contributes to genetic variation by combining DNA from two parents into a single chromosome In humans, an average of one to three crossover events occur per chromosome © 2021 Pearson Education, Inc. Figure 13.12 © 2021 Pearson Education, Inc. Animation: Genetic Variation from Independent Assortment of Chromosomes © 2021 Pearson Education, Inc. Animation: Genetic Variation from Crossing Over © 2021 Pearson Education, Inc. Random Fertilization Random fertilization adds to genetic variation because any sperm can fuse with any ovum (unfertilized egg) The fusion of two gametes (each with 8.4 million possible chromosome combinations from independent assortment) produces a zygote with any of about 70 trillion diploid combinations © 2021 Pearson Education, Inc.  Crossing over adds even more variation Each zygote has a unique genetic identity © 2021 Pearson Education, Inc. The Evolutionary Significance of Genetic Variation Within Populations Natural selection results in the accumulation of genetic variations favored by the environment Mutations are the original source of different alleles These are mixed and matched during meiosis Sexual reproduction is almost universal among animals Asexually reproducing organisms like the bdelloid rotifer increase genetic diversity by incorporating foreign DNA from the environment © 2021 Pearson Education, Inc. Figure 13.13 © 2021 Pearson Education, Inc. Figure 13-eco-01 © 2021 Pearson Education, Inc. Figure 13-eco-02 © 2021 Pearson Education, Inc. Figure 13-eco-03 © 2021 Pearson Education, Inc.