Anaerobic Metabolism in Children PDF

ANAEROBIC METABOLISM IN CHILDREN PEDIATRIC EXERCISE SCIENCE (KIN 3382)  KINE 3382 REMINDERS Guest Lecture  next two Thursdays (Feb 6th & 13th) Quiz #2  February 11th (next week) Midterm  February 27th CONCEPT REVISION BASIC CONCEPTS IN EXERCISE PHYSIOLOGY ATP-PC SYSTEM...

ANAEROBIC METABOLISM IN CHILDREN PEDIATRIC EXERCISE SCIENCE (KIN 3382)  KINE 3382 REMINDERS Guest Lecture  next two Thursdays (Feb 6th & 13th) Quiz #2  February 11th (next week) Midterm  February 27th CONCEPT REVISION BASIC CONCEPTS IN EXERCISE PHYSIOLOGY ATP-PC SYSTEM ATP ADP Molecule Molecule A + P P P + H2O A + P P + Pi +Energy Hydrolysis Energy Store Energy Used Muscle Contraction 2-Sec. BASIC CONCEPTS IN EXERCISE PHYSIOLOGY ATP-PC – ATP RESYNTHESIS Creatine ADP Molecule C + P A + P P + Pi Creatine Phosphate Creatine ATP synthase Kinase Pi Enzyme Enzyme ATP Molecule 10-Sec.  BASIC CONCEPTS IN EXERCISE Glycogen- phosphorylase Hexokinase Glucose-6 PHYSIOLOGY Glucose Investment Phosphate Glucose-P- GLYCOLYSIS ADP ATP isomerase SYSTEM Fructose-6 Phosphate Lactate Phosphofructosekina ADP ATP se Fructose-1,6 Lactate Biphosphate Dehydrogena Aldolase se Pyruvate Glyceraldehyde Glyceraldehyde 3-phosphate 3-phosphate Phosphoenolopyruvate 1 molecule Pyruvate kinase Pay off 3- diphosphoglycerate ADP ATP Phosphoglycerate ADP ATP kinase 3 2 Phosphoglycerate Phosphoglycerate Phosphoglycerate mutase  BASIC CONCEPTS IN EXERCISE PHYSIOLOGY GLCOLYSIS - ATP RESYNTHESIS Anaerobi c Glycolytic pathway is capable of resynthesizing ATP rapidly ATP produced by this system is quite limits Key limiting enzymes in glycolytic cascade: Glycogen-phosphorylase  converts glycogen to glucose-6- phosphate Phosphofructokinase  converts fructose-6-phosphate to fructose-1,6- diphosphate Aerobic BASIC CONCEPTS IN EXERCISE PHYSIOLOGY AEROBIC VS. ANAEROBIC Aerobic 12% 15 sec burst of maximal exercise Anaerobic 88% Anaerob ic 20% 4 min burst of exercise Aerobic 80% BASIC CONCEPTS IN EXERCISE PHYSIOLOGY MIXTURE OF AEROBIC & ANAEROBIC METABOLISM Short-Burst Activities and Anaerobic Metabolism: 19 to 44% of energy used during a Wingate test comes from aerobic sources (Chia et al., 1997) Aerobic contribution of a Wingate test is 26% in children (Counil et al., 1997) In a child-to-adult comparison, aerobic input to a Wingate tests was 34% in boys (aged 9-12) and 23% in men (aged 19-23) (Hebestreit et al., 1993) ANAEROBIC FITNESS TERMINOLOGY Peak Power: the highest mechanical power that is generated during a