Lecture 6 - Sleep & Memory PDF

Lecture 6 - Sleep & Memory Overview Sleep and its elecrophysical signatures History of memory and sleep Sleep study designs Theories and seminal findings Conclusion Sleep Definition of Sleep Sleep is a naturally recurring state of relatively suspended sensory and motor...

Lecture 6 - Sleep & Memory Overview Sleep and its elecrophysical signatures History of memory and sleep Sleep study designs Theories and seminal findings Conclusion Sleep Definition of Sleep Sleep is a naturally recurring state of relatively suspended sensory and motor activity, characterised by total or partial unonsciousness It is distinguished from quiet wakefulnessby a decreased ability to react to stimuli, and is more easily reversible than a coma While asleep, the brain in humans undergoes a unique cycle of brain-wave activity that includes of dreaming Brain Activity During Sleep We perform polysomnography Electoencephalography (EEG, brain activity) Electrooculography (EOG, eye movements) Electromyography (EMG, muscle activity) The sleeping brain is not dormant, it oscillates NREM vs REM Sleep NREM N1: transition from wake to sleep, rolling eye-movements (5-10% sleep) N2: light sleep, characterised by sleep spindles and K-complexes (45-60% of sleep) N3: deep sleep or slow-wave sleep (SWS) characterised by slow oscillations (