LS-HEH I 201-Hematology I White Blood Cells PDF

LS-HEH I 201-Hematology I White Blood Cells Asaad Mohammed Ahmed (Leukocytes) Associate Professor In Hematology BSc, MSc, PhD، H (ASCPi)، SH (ASCPi)Hematology 1  General introduction White blood cells (WBCs), or leukocytes, ar...

LS-HEH I 201-Hematology I White Blood Cells Asaad Mohammed Ahmed (Leukocytes) Associate Professor In Hematology BSc, MSc, PhD، H (ASCPi)، SH (ASCPi)Hematology 1  General introduction White blood cells (WBCs), or leukocytes, are a part of the immune system and help our bodies fight infection. They circulate in the blood so that they can be transported to an area where an infection has developed. In a normal adult body, there are 4,500 to 11,000 WBCs per microliter (4.5 to 11.0 × 109/L). (average 7,000).  Hematopoiesis general myeloid tissue lymphoid tissue  Hematopoiesis general myeloid tissue bone marrow lymphoid tissue  Hematopoiesis general myeloid tissue bone marrow erythrocytes platelets granulocytes monocytes lymphoid tissue  Hematopoiesis general Myeloid tissue bone marrow erythrocytes platelets granulocytes monocytes Lymphoid tissue thymus lymph nodes spleen Leukocyte Descriptions (WBCs) Granulocytes - Eosinophils - 2-4% - Basophils - sieve-like appearance  Promyelocyte cell division: + -5% of nucleated cells in BM size: 20 mm diameter cytoplasm: deep blue azurophilic granules abundant rER, free ribosome numerous mitochondria well developed Golgi nucleus: round to ovoid occasionally indented prominent nucleoli  Myelocyte cell division: + 5-20% of nucleated cells in BM cytoplasm: specific granules decreased in basophilia nucleus: ovoid irregular shape disappearing of nucleoli dense and compact chromatin  Metamyelocyte no more cell division ~22% of nucleated cells in BM size: 10-18 mm diameter (slightly larger than mature PMN) cytoplasm: prominent secondary granules nucleus: slightly indented, kidney-shaped dense chromatin no nucleolus Granulocyte maturation stem cell: