Summary

This document provides information on ketamine, including its mechanisms of action, indications, contraindications, adverse reactions, and routes of administration. It also details the onset and duration of action for different routes.

Full Transcript

GENERIC NAME ketamine TRADE, BRAND, OR PROPRIETARY NAME Ketalar® CLASSES Sedative Anesthetic Analgesic STANDARD SUPPLY Vial MECHANISMS OF ACTION Blocks pain receptors Produces a dissociative state Produces anesthesia INDICATIONS Procedural sedation for rapid sequence intubation Chemical restraint fo...

GENERIC NAME ketamine TRADE, BRAND, OR PROPRIETARY NAME Ketalar® CLASSES Sedative Anesthetic Analgesic STANDARD SUPPLY Vial MECHANISMS OF ACTION Blocks pain receptors Produces a dissociative state Produces anesthesia INDICATIONS Procedural sedation for rapid sequence intubation Chemical restraint for agitated (excited) delirium Pain management CONTRAINDICATIONS Known hypersensitivity to the drug Not recommended for use with pediatric patients ADVERSE REACTIONS/SIDE EFFECTS Respiratory depression Respiratory arrest Bradycardia Tachycardia Dysrhythmias Hallucinations Nausea Vomiting ROUTES OF ADMINISTRATION IV IO IM KETAMINE 1 ONSETS OF ACTION IV/IO: less than 1 minute IM: 3 to 4 minutes ADULT DOSAGES IV/IO: 1.0 to 2.0 mg/kg over 1 minute IM: 2.0 to 4.0 mg/kg SPECIAL CONSIDERATION The peak effect of IV/IO administration of the drug is 15 minutes The peak effect of IM administration of the drug is 30 to 45 minutes The duration of IV/IO administration of the drug is 15 to 60 minutes The duration of IM administration of the drug is 15 to 60 minutes The duration of rectal administration of the drug is variable KETAMINE 2

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