Interstitial Keratitis - A Comprehensive Overview - PDF
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Alex Hynes OD FAAO
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Summary
This presentation provides a thorough overview of Interstitial Keratitis, an eye disease involving the corneal stroma. It details various aspects including causes like syphilis, clinical presentation, and potential treatments. The presentation emphasizes the different types of vessels and structures found in the eye.
Full Transcript
Interstitial Keratitis Alex Hynes OD FAAO What is interstitial keratitis? _____-ulcerating vascular-inflammation of K stroma _______________ nations ____________ endpoint several diseases Potentially blinding Therapy effective if given ________ Syphilitic Interstitial Ke...
Interstitial Keratitis Alex Hynes OD FAAO What is interstitial keratitis? _____-ulcerating vascular-inflammation of K stroma _______________ nations ____________ endpoint several diseases Potentially blinding Therapy effective if given ________ Syphilitic Interstitial Keratitis Congenital Syphilis Etiology in _________of bilateral IK cases Acquired Syphilis (& HSK) Unilateral IK However, _____________ segment involvement = more likely Interstitial Keratitis 1= posterior stromal scarring 2= blood vessel? Interstitial Keratitis Superficial BV’s Deep BV’s IK Clinical Pres Initial symptoms= pain, tearing, photophobia, perilimbal injection Early Signs: Sectoral superior stromal inflammation KP’s Late Signs: Deep K vascularization Can become so intense K = pink Ultimately: K scarring, ghost vessels VA ↓’d Irregular cyl and/or stromal opacification Ghost Vessels Clearer lines = bv’s Interstitial Keratitis 2/2 Syphilis Salmon patch (deep stromal NV) Interstitial Keratitis 1= deep stromal scarring 2= ghost vessels Seropositive adult Had bilateral keratitis during childhood Congenital Syphilis Dental deformities CN VIII (vestibulocochlear) Bone & Cartilage abnormalities Saddle nose, saber shins, frontal bossing Cognitive impairment ______________________ triad: Teeth, deafness, IK Syphilitic IK Manifestations in 1st 2 yrs: Infectious IK generally= later immune mediated manifestation __________________ decade Other causes of IK Other (rare) causes of IK Mycobacterium tuberculosis Mycobacterium leprae Borrelia burgdoferi (Lyme Disease) Measles Epstein-Barr virus (infectious mononucleosis) C trachomatis Leishmania Onchocerca volvulus (onchocerciasis) *IK doesn’t always ≠ active infection → immune rxn Onchocerciasis Aka ___________________-blindness Onchocerca volvulus nematode Human hosts Simulium blackfly Tx: ivermectin q6mo Adjunctive= doxycycline Cogan syndrome Rare autoimmune disorder Young adults Stromal keratitis Tx= topical steroid Vertigo Hearing loss Urgent prednisolone p.o. Systemic vasculitis Polyarteritis nodosa
