GIT Microbiology PDF

Summary

These notes cover various aspects of microbiology related to the Gastrointestinal Tract (GIT). Topics include staphylococcal food poisoning, symptoms, sources, and detection methods. Other intestinal diseases like neurocysticercosis and ancylostamiasis are also briefly discussed.

Full Transcript

GIT Microbiology Anurag Kothari VMMC 2020 LEE W / locus of say trone syte effacement factor (simula to susgeben) - demonst...

GIT Microbiology Anurag Kothari VMMC 2020 LEE W / locus of say trone syte effacement factor (simula to susgeben) - demonstrate test · by stery - -aswenes - rabid eye jeduati - - sorbital nonfermenter In all Eval are sabitos flementer * STAPHYLOCOCLAL FOOD POISONING Infected laued by contamination carriers of food from. herman. 1. Enterotonin formed by of S strains -> Sot. aureus. preformed town (secreted food before ~ in - consumption perised sheet 11-6 has) -> Incubation is -> Staph. enterotonin is heat stable Site of action 2. You stimulates vagus nerve -> vomiting centre ofbrain I intestinal - peristaltic acurly.. · 3. Symptoms -> Nausea , reprniting Occasionally and diar hoea hypotension > , dehydration No fever -> -> Symptoms resolve within 8-10 his 4 Source of infection · Food Infected Dairyproduct Harve item -> such as , , foultay , salad , Mayorais s. Serotyping Enterotonins be typed into IS serotypes -> can (A-E G-P) All , a act as superantigens. Type A most common to food · is cause poisoning. Serotype-F does not cause food poisoning · , but tonic stock causes syndrome Detection of enterotoim laten - caused by ELISA/ agglutination - lest Detection of enterotonin -> gene by PCR multiples. 7. Treatment electrolyte imbalance corresting flied and -. * DIAGNOSIS : Sulture and Identification -> Yood culture Pre-enrichment culture - Pathogenie bacteria isolated from suspected foods also be by agan - can culture after fore-eneachment I wish helps in recovery of any damaged organisms) selective enrichment This is followed by focomoting the growth of target organism. -> stool culture 2. PCR Detect gene encoding for toxin ELISA) Later tests. 3 Agglutination Detection stool of entero-tow in * TREATMENT Gild Diseases 1. Self-limiting and Adequate electrolyte h i d e rat i on 2. supplementation solution rehydration Ocal (ORS > -> Interacenous solutions Ringe lastate sol eg - :. Isotonic Nal sol. 3 Symptomatic treatment : Antipyretic -> > Anti-spasmodic -> Probiotics sever Diseases 4 Imore Anti-towins effective : Eg : Heflavalent botulin equine ↳ server anti-town-for food botulism s. Antibiotics , do not have much role because bacteria have already produced the tonin > Eg Botulism- Dinillin - metronidazole or shigellosis Jeuoroquinolone - leg ciprofronaien) Cholera Azithromyin is DO L.. e transplant inmediately ↳ Sach's buffered sale generat Berechermal I- C-0- Alhale/Aca 4) TS7 s. ) Manches Fermenters except 3- depentertas I I S I I I I 99 Comma shaped GNB- hich in stream appearance * Host - 1 (Many morpalogy I cyst sinfectives forme traphozpite - ~ ~ - Intestinal Terass NEUROCYSTICERCOSIS Saturday, 1 January 2022 4:35 PM Loeffler Pulmonary opt Mechanical abster in Intesting, Respiration truct a bidinI obstruction , Malnutritn -- ~culdren , Ancylostamiasis 2 : ground itch Abd pain Diaraloca resicides eupHou · , ofentry at point Iron · defansia Estanon. 3 carva regar n. Pulscionary ~ cosinophiles CUTANEOUS LARVA MIGRANS Saturday, 1 January 2022 12:46 PM R Tonocariasis - Albendazole 3 days De Mebendazole for 21 days with gluso-cortrioids Cutasaus Goa Oral and topical thirbendazole is Megacam- effectives -> Freezing the advancing end of keeping exception in ethys reoside useful is \.;,.. 1 17 - ~ta'~;,- ifel s1,41 pfo Off""m""""9--0""'""""'e''-'----- ~~'!~:::1=W~S:--=--1f'-'~~=====:=Jd:::'-,:":'.v½A'='='==_____ _ ~,a\,-, _______________,~,,~~~,__,_-,...____- - - /', ~\'\.P----------------------------- ~as'""' 10.,J cgfu,-JH- ~ _· _ '---'M'-'-"'"""'pl;""'g,.,___ - _ _c..- c..._F_A_ __..1.{__c_c..._'{_ A___ _ ~,-, d6-f ct- ~ule..... Ceff !Uft" ~-, _ _ _ _ _ _ _ _ _ _ _ _ _ _ _i: ~00~ ~~ + ""'1q~Cii-::i c,_ s~ +

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