Summary

This document discusses hypertension, a cardiovascular disorder. It provides classifications, pathophysiology, and treatment options, along with clinical presentations, diagnosis, and compelling indications for certain drugs for hypertension. Relevant sections include treatments, pharmacologic therapy, and special populations such as older persons and children/adolescents.

Full Transcript

College of Pharmacy Fourth year. Clinical Pharmacy Cardiovascular disorders Hypertension Introduction 1-Hypertension is defined as persistently elevated arterial blood pressure (BP). (See Table -1 for the classification of BP in adults). Table-1: Classification of Blood Pressure in Adults 2-Isolated...

College of Pharmacy Fourth year. Clinical Pharmacy Cardiovascular disorders Hypertension Introduction 1-Hypertension is defined as persistently elevated arterial blood pressure (BP). (See Table -1 for the classification of BP in adults). Table-1: Classification of Blood Pressure in Adults 2-Isolated systolic hypertension is diastolic blood pressure (DBP) 180/120 mm Hg) is categorized as hypertensive emergency (extreme BP elevation with acute or progressing end-organ damage) or hypertensive urgency (extreme BP elevation without acute or progressing end-organ injury). Pathophysiology 1-Hypertension may result from an unknown etiology (primary or essential hypertension) or from a specific cause (secondary hypertension). 2-Secondary hypertension (

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