Heart Conditions PDF
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McMaster University
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Summary
This document provides information about various heart conditions, including congestive heart failure, myocardial infarction (heart attack), angina pectoris, and coronary artery disease. The document details the definitions, causes, symptoms, and treatments for each condition.
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1. Congestive Heart Failure (CHF): De nition: A chronic condition where the heart cannot pump blood effectively to meet the body’s needs. Causes: ◦ Coronary artery disease (CAD) ◦ Hypertension ◦...
1. Congestive Heart Failure (CHF): De nition: A chronic condition where the heart cannot pump blood effectively to meet the body’s needs. Causes: ◦ Coronary artery disease (CAD) ◦ Hypertension ◦ Valvular heart disease Symptoms: ◦ Fatigue, shortness of breath (dyspnea), swelling in legs/feet (edema) ◦ Fluid retention leading to pulmonary congestion Types: ◦ Left-sided: Affects the lungs (pulmonary symptoms). ◦ Right-sided: Causes systemic symptoms (edema, ascites). Treatment: ◦ Lifestyle changes: low-sodium diet, exercise. ◦ Medications: diuretics, ACE inhibitors, beta-blockers. ◦ Advanced cases: implantable devices or heart transplant. ◦ Main goal: reduce uid retention ◦ heart’s reduced ability to pump blood effectively, causing uid buildup in tissues (edema) and lungs 2. Myocardial Infarction (MI): De nition: Commonly known as a heart attack, it occurs when blood ow to the heart muscle is blocked, leading to tissue damage or death. Causes: ◦ Blockage in coronary arteries due to atherosclerosis or a clot. Symptoms: ◦ Chest pain (often radiating to the arm, jaw, or back), shortness of breath, nausea, cold sweat. ◦ Symptoms can be atypical in women and diabetics (e.g., fatigue, indigestion-like pain). Diagnosis: ◦ ECG changes, elevated cardiac biomarkers (e.g., troponins). Treatment: ◦ Immediate: aspirin, nitroglycerin, oxygen, thrombolytics, or percutaneous coronary intervention (PCI). ◦ Long-term: statins, ACE inhibitors, beta-blockers, lifestyle modi cations. fi fi fl fl fi fl 3. Angina Pectoris: De nition: Chest pain or discomfort caused by insuf cient blood ow to the heart muscle (ischemia), often triggered by exertion or stress. Types: ◦ Stable Angina: Predictable; occurs with exertion, relieved by rest or nitroglycerin. ◦ Unstable Angina: Occurs unpredictably; a medical emergency. ◦ Prinzmetal’s (Variant) Angina: Caused by coronary artery spasm, not necessarily linked to exertion. Symptoms: ◦ Pressure, tightness, or burning sensation in the chest. Treatment: ◦ Acute: nitroglycerin. ◦ Chronic: beta-blockers, calcium channel blockers, lifestyle changes, revascularization (e.g., stenting) ◦ Nitrates ◦ Beta blockers ◦ Calcium channel blockers ◦ Main goal: dilate blood vessels, reducing the heart's oxygen demand, or improving the heart's ef ciency. 4. Coronary Artery Disease (CAD): De nition: Narrowing or blockage of the coronary arteries due to plaque buildup (atherosclerosis), reducing blood ow to the heart. Further classi ed as: ▪ Arteriosclerosis ▪ Atherosclerosis ▪ Angina ▪ MI Risk Factors: ◦ Smoking, high cholesterol, hypertension, diabetes, obesity, sedentary lifestyle. Symptoms: ◦ Often asymptomatic until signi cant blockage develops. ◦ Angina, shortness of breath, fatigue. Complications: ◦ Can lead to MI, heart failure, arrhythmias. Treatment: ◦ Medications: statins, antiplatelets, ACE inhibitors. ◦ ACE: lower BP, ◦ ARBS (sartan) ◦ Antiplatelets (e.g., aspirin, clopidogrel): Prevent blood clots. ◦ Statins (e.g., atorvastatin, rosuvastatin): Lower LDL cholesterol fi fi fi fi fi fl fi fl ◦ Statins are drugs that can lower your cholesterol ◦ Lifestyle: diet, exercise, smoking cessation. ◦ Procedures: PCI (stent placement), coronary artery bypass grafting (CABG). ◦ Main goal: improve blood ow to the heart, 5. Arrhythmias: De nition: Abnormal heart rhythms that can be too fast (tachycardia), too slow (bradycardia), or irregular. Types: ◦ Atrial Fibrillation (AFib): Irregular, rapid atrial activity; increases stroke risk. ◦ Ventricular Tachycardia/Fibrillation: Life-threatening; requires immediate treatment. ◦ Bradyarrhythmias: Slow rhythms; may need a pacemaker. ◦ Supraventricular Tachycardia (SVT): Rapid rhythm originating above the ventricles. Causes: ◦ Electrolyte imbalances, CAD, heart failure, medications, structural heart disease. Symptoms: ◦ Palpitations, dizziness, fainting, chest discomfort. Treatment: ◦ Procedures: cardioversion, catheter ablation, implantable devices ◦ Medications ◦ Class I - sodium channel blockers ◦ Class 2 - beta blockers ◦ Class 3 - “amiodarone” ◦ Class 4 - calcium channel blockers fi fl 1. Arteriosclerosis (CAD) De nition: A general term for the thickening, hardening, and loss of elasticity of arterial walls. Cause: Aging, hypertension, and wear-and-tear on blood vessels. Impact: Reduces the exibility of arteries, leading to increased blood pressure and impaired circulation. Key Point: It is a broad category of arterial diseases, including atherosclerosis. 2. Atherosclerosis (CAD) De nition: A speci c type of arteriosclerosis characterized by the buildup of fatty deposits (plaques) in the arterial walls. Cause: High cholesterol, smoking, hypertension, and diabetes. Impact: ◦ Narrows the arteries, restricting blood ow. ◦ Increases the risk of blood clots, leading to angina, heart attacks, or strokes. Key Point: Atherosclerosis is a form of arteriosclerosis but speci cally involves plaque buildup. 3. Angina (Chest Pain) De nition: A symptom of reduced blood ow to the heart muscle (ischemia) caused by narrowed or blocked coronary arteries. Cause: Often due to atherosclerosis or coronary artery spasm. Types: ◦ Stable Angina: Predictable; occurs during exertion and is relieved by rest or nitroglycerin. ◦ Unstable Angina: Occurs unpredictably; signals a higher risk of heart attack. ◦ Variant Angina: Caused by coronary artery spasms, not blockages. Impact: Temporary pain or discomfort; does not cause permanent heart damage. Key Point: Angina is a symptom, not a disease. fi fi fi fi fl fl fl fi 4. Myocardial Infarction (MI) De nition: Commonly called a heart attack, it occurs when blood ow to a part of the heart is completely blocked, causing damage or death to heart muscle tissue. Cause: Often due to the rupture of an atherosclerotic plaque leading to a blood clot. Symptoms: ◦ Severe chest pain or pressure, not relieved by rest. ◦ Shortness of breath, nausea, sweating. ◦ Can present atypically in some individuals (e.g., women, diabetics). Impact: ◦ Permanent damage to heart muscle. ◦ Can lead to heart failure or fatal arrhythmias if untreated. Key Point: MI is a life-threatening event caused by prolonged ischemia. fi fl