Gastrointestinal Tract & HPB PDF
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This document discusses the gastrointestinal tract (GIT) and hepatobiliary system (HPB), covering various aspects such as cancer types in the oesophagus, stomach, and related conditions, including their causes and treatments. The information presented is relevant for post-graduate level medical studies.
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GASTROINTESTINA L TRACT OESOPHAGUS SQUAMOUS CELL CARCINOMA Elderly, mainly males Tobacco, alcohol, GORD Often present late (Stage) – bad prognosis If caught early – good prognosis Diagnosis by biopsy OESOPHAGUS ADENOCARCINOMA 50% of oesophageal cancers Arise i...
GASTROINTESTINA L TRACT OESOPHAGUS SQUAMOUS CELL CARCINOMA Elderly, mainly males Tobacco, alcohol, GORD Often present late (Stage) – bad prognosis If caught early – good prognosis Diagnosis by biopsy OESOPHAGUS ADENOCARCINOMA 50% of oesophageal cancers Arise in Barrett’s due to GORD, association with hiatus hernia Inflammation, ulceration, metaplasia, dysplasia (5-10%) STOMACH ADENOCARCINOMA >90% stomach cancers (half in antrum) 3% cancer deaths Elderly, poor prognosis unless early Helicobacter pylori, AI gastritis, smoking
