Cancer Statistics for 2024 PDF
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Uploaded by RightSunflower
The University of Texas at Dallas
2024
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Summary
This document provides information about the leading cancer types and their statistics for the year 2024, as well as the factors that can cause cancer, exploring the genetic mutations and other aspects related to genomics. Keywords include cancer, genetics, mutations, and oncology.
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Ten leading cancer types for the estimated new cancer cases and deaths by sex, United States, 2024 Rebecca Sieg et al. 2024, Cancer sta L. el tistics. Cancer and genome Genome: the complete set of genes or...
Ten leading cancer types for the estimated new cancer cases and deaths by sex, United States, 2024 Rebecca Sieg et al. 2024, Cancer sta L. el tistics. Cancer and genome Genome: the complete set of genes or genetic material present in a c ell Carcinogen: or organism. a substance, organism or agent capable of c ausing cancer. Mutagen: an agent, such as radiation or a chemical substance, which causes Types of mutati ons: geneticmutation. Substitutions/ Transition a purine orsubstitution: pyrimidine being replaced by a base of the same kind. point mutations: those mutations that affect a single base pair. Transversionsubstitution: silent mutations: code for athe purine samebeing aminoreplaced acid, by to due a pyrimidine, the or vice degeneracy of versa. the gene tic code, usually a substitution in the third missense mutation: the base of a codon, substitution known results as the for in a codon wobble position. a different amino acid. nonsense mutation: the substitution results in the formation of a stop codon. Insertions and Dele frameshift mutations: shift the reading frame of the codons. tions Translocation: a piece of DNA from one chromosome get moved to another chromosome or to a nother region of the same chromosome Cancer and Types of mutati genome ons: Germline mutations: changes to your DNA that you inherit from the egg and sperm cells d uring conception. Somatic mutations: Other and sperm.changes to your DNA that happen after conception to cells other than chang the egg Epigenetic change: a reversible mechanism in regulating the function of the genome with es: out altering DNA underlying the sequence of the genome. E. g., DNA methylation, histone modification, chromatin remodeling , Extrachromosomal non‐coding DNA (ecDNA): RNA (ncRNA) a distinct regulation, and RNA type of DNA that does not reside on a chro modification. mosome, is circular. Factors Causing Genetics:
