Essentials of Biochemistry 2 PDF

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co co co co co m m m m m m m m m m m eb eb eb eb eb e o ok oo oo oo oo s ks ks k sf ks fre fre fre re fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre fre fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re fre e. e. e. e. e. co co co co c m m m m om m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re f re e. e. e. e. e. co co co c co m m m om m  co co co co co m m m m m m m m m m m eb eb eb eb eb e o ok oo oo oo oo s ks ks k sf ks fre fre fre re fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre fre fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re fre e. e. e. e. e. ESSENTIALS OF co co co co c m m m m om BIOCHEMISTRY m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re f re e. e. e. e. e. co co co c co m m m om m  co co co co co m m m m m m m m m m m eb eb eb eb eb e o ok oo oo oo oo s ks ks k sf ks fre fre fre re fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre fre fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re fre e. e. e. e. e. co co co co c m m m m om m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re f re e. e. e. e. e. co co co c co m m m om m  co co co co co m m m m m m m m m m m eb eb eb eb eb e o ok oo oo oo oo s ks ks k sf ks fre fre fre re fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre fre fre e. e. e. e. e. co co co co co m m m m m Professor Pankaja Naik m m m m m m PhD e Nashik, Maharashtra, India eb eb eb eb eb Department of Biochemistry oo oo oo oo oo Second Edition ks ks ks ks ks fre fre fre f re fre New Delhi | London | Philadelphia | Panama The Health Sciences Publisher SMBT Institute of Medical Sciences and Research Center e. e. e. e. e. ESSENTIALS OF co co co co c m m m m om BIOCHEMISTRY m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re f re e. e. e. e. e. co co co c co m m m om m  e e e e m m m m m m m om m co co co co c e. e. e. e. fre fre fre f re ks ks ks ks oo oo oo oo eb eb eb eb Jaypee Brothers Medical Publishers (P) Ltd m m m m Headquarters Jaypee Brothers Medical Publishers (P) Ltd m m m m om 4838/24, Ansari Road, Daryaganj co co co co New Delhi 110 002, India c Phone: +91-11-43574357 e. e. e. e. Fax: +91-11-43574314 Email: [email protected] re fre re re sf f f Overseas Offices ks ks ks k J.P. Medical Ltd Jaypee-Highlights Medical Publishers Inc Jaypee Medical Inc oo oo oo oo 83 Victoria Street, London City of Knowledge, Bld. 235, 2nd Floor, Clayton 325 Chestnut Street SW1H 0HW (UK) Panama City, Panama Suite 412, Philadelphia, PA 19106, USA eb eb eb eb Phone: +44 20 3170 8910 Phone: +1 507-301-0496 Phone: +1 267-519-9789 Fax: +44 (0)20 3008 6180 Fax: +1 507-301-0499 Email: [email protected] m m m m Email: [email protected] Email: [email protected] Jaypee Brothers Medical Publishers (P) Ltd Jaypee Brothers Medical Publishers (P) Ltd 17/1-B Babar Road, Block-B, Shaymali Bhotahity, Kathmandu, Nepal m m m m m Mohammadpur, Dhaka-1207 Phone +977-9741283608 Bangladesh Email: [email protected] co co co co co Mobile: +08801912003485 Email: [email protected] e. e. e. e. fre fre fre fre Website: www.jaypeebrothers.com Website: www.jaypeedigital.com ks ks ks ks oo oo oo oo © 2017, Jaypee Brothers Medical Publishers The views and opinions expressed in this book are solely those of the original contributor(s)/author(s) and do not necessarily represent those eb eb eb eb of editor(s) of the book. m m m m All rights reserved. No part of this publication may be reproduced, stored or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission in writing of the publishers. All brand names and product names used in this book are trade names, service marks, trademarks or registered trademarks of their respective owners. The publisher is not associated with any product or vendor mentioned in this book. m m m m m Medical knowledge and practice change constantly. This book is designed to provide accurate, authoritative information about the subject co co co co co matter in question. However, readers are advised to check the most current information available on procedures included and check information from the manufacturer of each product to be administered, to verify the recommended dose, formula, method and duration of e. e. e. e. administration, adverse effects and contraindications. It is the responsibility of the practitioner to take all appropriate safety precautions. fre fre fre fre Neither the publisher nor the author(s)/editor(s) assume any liability for any injury and/or damage to persons or property arising from or related to use of material in this book. ks ks ks ks This book is sold on the understanding that the publisher is not engaged in providing professional medical services. If such advice or services are required, the services of a competent medical professional should be sought. oo oo oo oo Every effort has been made where necessary to contact holders of copyright to obtain permission to reproduce copyright material. If any have been inadvertently overlooked, the publisher will be pleased to make the necessary arrangements at the first opportunity. eb eb eb eb m m m m Inquiries for bulk sales may be solicited at: [email protected] Essentials of Biochemistry First Edition: 2012 m m m m m Second Edition: 2017 co co co co co ISBN 978-93-86150-30-1 e. e. e. e. fre fre fre fre Printed at s ks ks ks ok oo oo oo o eb eb eb eb m m m m  co co co co co m m m m m m m m m m m eb eb eb eb eb e o ok oo oo oo oo s ks ks k sf ks fre fre fre re fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre fre fre e. e. e. e. e. co co co co co m m m m m My Parents m m m m m m Dedicated to eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re fre e. e. e. e. e. co co co co c m m m m om m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re f re e. e. e. e. e. co co co c co m m m om m  co co co co co m m m m m m m m m m m eb eb eb eb eb e o ok oo oo oo oo s ks ks k sf ks fre fre fre re fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre fre fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re fre e. e. e. e. e. co co co co c m m m m om m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re f re e. e. e. e. e. co co co c co m m m om m  e e e e m m m m m m m om m co co co co c e. e. e. e. fre fre fre f re ks ks ks ks Preface oo oo oo oo eb eb eb eb m m m m This second edition of Essentials of Biochemistry is a clear, concise, comprehensive and in full color, exam oriented m m m m om ideal textbook for medical, dental, physiotherapy, occupational therapy, nursing and other health sciences students. co co co co This book is revised and updated keeping in view all categories of students and it addresses their needs in a simple c manner. Essentials of Biochemistry has been streamlined to focus on only the most essential biochemical concepts e. e. e. e. and avoids details not required by undergraduate students. Additional information has been given in the form of re fre re re diagrams, tables, and flowcharts to understand the topics and its proper perspective. sf f f ks ks ks The text has been so presented that the students would find it easy to attempt any question in the form of k objective type or essay type after going through the text. To facilitate the student learning, I have added new oo oo oo oo features: eb eb eb eb Exam questions in the form of long answer questions (LAQs), short answer questions (SAQs), multiple choice questions (MCQs), and clinical case studies. m m m m A glossary with precise definitions of the most common words of biochemical sciences. A list of reference/normal values for selected biochemical laboratory tests. After reading this book, reader suggestion and healthy criticism will be of great help in the future m m m m m improvement of the book. I would like you to send me your feedback at [email protected]/ co co co co co [email protected] e. e. e. e. fre fre fre fre Pankaja Naik ks ks ks ks oo oo oo oo eb eb eb eb m m m m m m m m m co co co co co e. e. e. e. fre fre fre fre ks ks ks ks oo oo oo oo eb eb eb eb m m m m m m m m m co co co co co e. e. e. e. fre fre fre fre s ks ks ks ok oo oo oo o eb eb eb eb m m m m  co co co co co m m m m m m m m m m m eb eb eb eb eb e o ok oo oo oo oo s ks ks k sf ks fre fre fre re fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre fre fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re fre e. e. e. e. e. co co co co c m m m m om m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re f re e. e. e. e. e. co co co c co m m m om m  e e e e m m m m m m m om m co co co co c e. e. e. e. fre fre fre f re ks ks ks ks Acknowledgments oo oo oo oo eb eb eb eb m m m m I express my profound gratitude to Honorable Shri Balasaheb Thorat (MLA and Trustee), and Honorable m m m m om Dr Sudhirji Tambe (MLA and Trustee), SMBT Sevabhavi Trust, Nashik, Maharashtra, India for their keen interest co co co co in all the academic activities of the faculty members. I sincerely express my gratitude to Dr Harshal Tambe, the c dynamic Managing Trustee, SMBT Sevabhavi Trust, Nashik, Maharashtra, India, for his continuous support and e. e. e. e. encouragement. re fre re re I am grateful to all my colleagues and students from various institutes and universities across the world as sf f f ks ks ks reviewers. Their suggestions and thoughtful comments have been of immense help to me in maintaining the k oo oo oo oo excellence of the second edition. I would like to acknowledge and thank the help rendered by Dr Pankaj Kamble, Dr Sandip Lambe and Ms Asmita Patil, my colleagues in the department. eb eb eb eb Special thanks to Mr SD Kurhe (Chief Officer) and Dr BM Deshpande (Administrative Officer), SMBT Sevabhavi m m m m Trust for all the cooperation extended by them to me. I profusely thank Mr Mukesh Kale, artist/DTP operator, Nashik, Maharashtra, India for his help in completing the script within the due period. m m m m m I am grateful to Shri Jitendar P Vij (Group Chairman) and Mr Ankit Vij (Group President), M/s Jaypee Brothers co co co co co Medical Publishers (P) Ltd, New Delhi, India for their motivating passion and all the timely help extended in e. e. e. e. bringing out the second edition. I wish to thank Mr Chandrashekhar S Gawade, Branch Manager, Mumbai, fre fre fre fre Maharashtra, India for his unfailing personal support in the preparation of the second edition. I also wish to thank Ms Payal Bharti (Project Manager), Mr Umar Rashid (Development Editor) and staff of Jaypee Brothers Medical ks ks ks ks Publishers for their cooperation and patience during the preparation and publication of the second edition. oo oo oo oo Last but not least, I thank my husband Mr Shekhar and my son Mr Sushrut for understanding and supporting me to complete the task successfully. eb eb eb eb m m m m m m m m m co co co co co e. e. e. e. fre fre fre fre ks ks ks ks oo oo oo oo eb eb eb eb m m m m m m m m m co co co co co e. e. e. e. fre fre fre fre s ks ks ks ok oo oo oo o eb eb eb eb m m m m  co co co co co m m m m m m m m m m m eb eb eb eb eb e o ok oo oo oo oo s ks ks k sf ks fre fre fre re fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre fre fre e. e. e. e. e. co co co co co m m m m m m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re fre e. e. e. e. e. co co co co c m m m m om m m m m m m eb eb eb eb eb e oo oo oo oo oo ks ks ks ks ks fre fre fre f re f re e. e. e. e. e. co co co c co m m m om m  e e e e m m m m m m m om m co co co co c e. e.