Endogenous and Exogenous Substances PDF
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Summary
This document discusses endogenous and exogenous substances, their definitions, and their importance in the human body. Key concepts like neurotransmitters, and various brain regions are explored. The document covers important topics in human biology and physiology.
Full Transcript
**Endogenous Substances** **Definition:** Endogenous substances are naturally occurring compounds produced by the body.\ **Importance:** They play vital roles in physiological processes, such as hormones (e.g., insulin) and neurotransmitters (e.g., dopamine). **Exogenous Substances** **Definition...
**Endogenous Substances** **Definition:** Endogenous substances are naturally occurring compounds produced by the body.\ **Importance:** They play vital roles in physiological processes, such as hormones (e.g., insulin) and neurotransmitters (e.g., dopamine). **Exogenous Substances** **Definition:** Exogenous substances originate from outside the body, such as drugs, toxins, and nutrients.\ **Importance:** Their effects can significantly impact bodily functions, sometimes beneficially (e.g., medications) or harmful (e.g., drugs). **Neurotransmitter** **Definition:** Neurotransmitters are chemical messengers that transmit signals across synapses between neurons.\ **Importance:** They are crucial for communication within the nervous system, affecting mood, perception, and bodily functions. **Acetylcholine** **Definition:** A neurotransmitter involved in muscle activation, memory, and learning.\ **Importance:** It plays a role in the autonomic nervous system and is linked to Alzheimer\'s disease when levels are disrupted. **Dopamine** **Definition:** A neurotransmitter associated with pleasure, motivation, and reward.\ **Importance:** It influences mood, attention, and motor control. Dysregulation is linked to disorders like Parkinson\'s and schizophrenia. **Norepinephrine** **Definition:** A neurotransmitter and hormone involved in the body\'s \"fight or flight\" response.\ **Importance:** It affects arousal, attention, and stress response. Abnormal levels can contribute to anxiety and depression. **Glutamate** **Definition:** The primary excitatory neurotransmitter in the brain.\ **Importance:** It plays a critical role in learning, memory, and overall brain function. Excessive glutamate can lead to neurotoxicity. **Serotonin** **Definition:** A neurotransmitter that regulates mood, appetite, and sleep.\ **Importance:** Low levels are linked to depression and anxiety disorders. Many antidepressants target serotonin pathways. **GABA (Gamma-Aminobutyric Acid)** **Definition:** The main inhibitory neurotransmitter in the brain.\ **Importance:** It helps regulate anxiety, muscle tension, and sleep. Many anti-anxiety medications enhance GABA activity. **Endorphin** **Definition:** Neurotransmitters that act as natural painkillers and mood enhancers.\ **Importance:** They are released during exercise, stress, and pain, contributing to feelings of euphoria. **Cerebral Hemispheres** **Definition:** The two halves of the brain, each responsible for different functions.\ **Importance:** The left hemisphere typically handles language and analytical tasks, while the right hemisphere is associated with creativity and spatial abilities. **Frontal Lobe** **Definition:** The brain region associated with reasoning, planning, problem-solving, and emotional regulation.\ **Importance:** It plays a crucial role in executive functions and personality. **Parietal Lobe** **Definition:** The region responsible for processing sensory information and spatial awareness.\ **Importance:** It integrates sensory inputs and contributes to perception and movement coordination. **Occipital Lobe** **Definition:** The visual processing center of the brain.\ **Importance:** It interprets visual stimuli and is essential for vision-related tasks. **Temporal Lobe** **Definition:** The area involved in auditory processing and memory.\ **Importance:** It plays a role in recognizing faces and understanding language. **Hypothalamus** **Definition:** A small brain region that regulates homeostasis, including temperature, hunger, and thirst.\ **Importance:** It links the nervous system to the endocrine system via the pituitary gland. **Pituitary Gland** **Definition:** The \"master gland\" that controls various hormonal functions.\ **Importance:** It regulates growth, metabolism, and reproductive processes through hormone release. **Amygdala** **Definition:** An almond-shaped structure involved in emotion processing and memory.\ **Importance:** It plays a crucial role in fear responses and emotional regulation. **Hippocampus** **Definition:** A brain region essential for memory formation and spatial navigation.\ **Importance:** It is involved in the consolidation of information from short-term to long-term memory. **Wilder Penfield** **Definition:** A neurosurgeon known for his pioneering work in mapping the brain\'s functions through electrical stimulation.\ **Importance:** His findings advanced understanding of the brain\'s cortical organization and treatment for epilepsy. **Motor Cortex** **Definition:** The area of the cerebral cortex that controls voluntary movements.\ **Importance:** Different regions correspond to different body parts, allowing precise movement control. **Somatosensory Cortex** **Definition:** The brain region that processes sensory input from the body.\ **Importance:** It interprets touch, temperature, pain, and proprioception. **Scanning Techniques** **Definition:** Various methods to visualize brain structure and activity.\ **Importance:** Techniques like EEG, CT, MRI, and PET provide insights into brain function and pathology. **EEG (Electroencephalogram)** **Definition:** A test that records electrical activity in the brain.\ **Importance:** It helps diagnose conditions like epilepsy and sleep disorders. **Brain Waves** **Definition:** Electrical impulses in the brain measured by EEG, categorized into delta, theta, alpha, beta, and gamma waves.\ **Importance:** Different brain states correspond to various mental activities and levels of consciousness. **CT Scan (Computed Tomography)** **Definition:** A medical imaging technique that uses X-rays to create detailed cross-sectional images of the body.\ **Importance:** Useful for diagnosing injuries and brain abnormalities. **MRI (Magnetic Resonance Imaging)** **Definition:** An imaging technique that uses strong magnets and radio waves to create detailed images of organs and tissues.\ **Importance:** Particularly effective for imaging the brain and spinal cord. **PET (Positron Emission Tomography)** **Definition:** An imaging test that uses radioactive tracers to visualize metabolic processes in the body.\ **Importance:** Useful for assessing brain function and diagnosing conditions like Alzheimer's. **Selective Attention** **Definition:** The process of focusing on a particular object or task while ignoring others.\ **Importance:** It enables efficient processing of relevant information in a complex environment. **Cameron Motte** **Definition:** A notable figure who underwent hemispherectomy to treat severe epilepsy.\ **Importance:** His case exemplifies brain plasticity and recovery after significant surgical intervention. **Hemispherectomy** **Definition:** A surgical procedure that involves removing or disconnecting one hemisphere of the brain.\ **Importance:** It is often performed to control severe epilepsy, particularly in children, with remarkable outcomes. **Neuroplasticity** **Definition:** The brain\'s ability to reorganize itself by forming new neural connections throughout life.\ **Importance:** It allows recovery from injury and adaptation to new experiences. **Divided Brain** **Definition:** Refers to the functional specialization of the two hemispheres of the brain.\ **Importance:** Each hemisphere has distinct roles, with the left typically associated with language and the right with spatial tasks. **Inattentional Blindness** **Definition:** A psychological phenomenon where individuals fail to perceive objects in their visual field when focused on a specific task.\ **Importance:** It highlights limitations in attention and awareness. **Monkey Business Illusion** **Definition:** A visual illusion that demonstrates inattentional blindness, where viewers miss obvious changes in a scene while focusing on a task.\ **Importance:** It illustrates how attention can affect perception. **Change Blindness** **Definition:** A phenomenon where a change in a visual stimulus goes unnoticed by the observer.\ **Importance:** It shows limitations in visual perception and attention. **Sequential Processing** **Definition:** A cognitive process that involves analyzing information one step at a time.\ **Importance:** It is often used in tasks requiring focused attention and logical reasoning. **Parallel Processing** **Definition:** The simultaneous processing of multiple aspects of information.\ **Importance:** It allows for quicker responses and the ability to manage complex stimuli. **Sensation** **Definition:** The process of detecting physical stimuli through sensory receptors.\ **Importance:** It is the first step in experiencing the world around us. **Perception** **Definition:** The interpretation and organization of sensory information.\ **Importance:** It enables individuals to make sense of their sensory experiences. **Absolute Threshold** **Definition:** The minimum level of stimulus intensity needed to detect a stimulus 50% of the time.\ **Importance:** It defines the limits of human perception. **Difference Threshold** **Definition:** The smallest detectable difference between two stimuli, also known as the just noticeable difference (JND).\ **Importance:** It helps understand sensory discrimination. **Signal Detection Theory** **Definition:** A theory that explains how we detect signals amidst noise, incorporating decision-making processes.\ **Importance:** It emphasizes the subjective nature of perception, influenced by various factors like expectations and biases. **Sensory Receptors** **Definition:** Specialized cells that detect sensory stimuli and convert them into neural signals.\ **Importance:** They are crucial for all sensory modalities, including vision, hearing, and touch. **Transduction** **Definition:** The process of converting physical energy from stimuli into electrical signals that can be interpreted by the brain.\ **Importance:** It is essential for all sensory systems. **Sensory Adaptation** **Definition:** The diminished sensitivity to a stimulus as a result of constant exposure.\ **Importance:** It allows individuals to focus on changes in the environment rather than constant stimuli. **Photons** **Definition:** The basic units of light and all other forms of electromagnetic radiation.\ **Importance:** They are crucial for vision, as light enters the eye in the form of photons. **Visible Spectrum** **Definition:** The portion of the electromagnetic spectrum that is visible to the human eye.\ **Importance:** It encompasses wavelengths from approximately 380 to 750 nanometers. **Cornea** **Definition:** The transparent front layer of the eye that helps focus light.\ **Importance:** It is crucial for clear vision, providing a protective barrier as 4o mini **Lens** **Definition:** A transparent structure behind the cornea that helps focus light onto the retina.\ **Importance:** It adjusts shape for near and distant vision through a process called accommodation. **Accommodation** **Definition:** The process by which the eye\'s lens changes shape to focus on objects at varying distances.\ **Importance:** It allows for clear vision across different ranges, critical for daily tasks. **Retina** **Definition:** The light-sensitive layer at the back of the eye that converts light into neural signals.\ **Importance:** Contains photoreceptors (rods and cones) essential for vision. **Rods** **Definition:** Photoreceptor cells in the retina that are sensitive to low light levels.\ **Importance:** They enable night vision and peripheral vision but do not detect color. **Cones** **Definition:** Photoreceptor cells in the retina responsible for color vision and detail.\ **Importance:** They function best in bright light and are concentrated in the fovea. **Fovea** **Definition:** A small central pit in the retina that provides the clearest vision.\ **Importance:** It is densely packed with cones, allowing for sharp central vision. **Optic Nerve** **Definition:** The nerve that transmits visual information from the retina to the brain.\ **Importance:** It is critical for the perception of sight, connecting the eye to the visual cortex. **Trichromatic Theory** **Definition:** A theory of color vision that states the eye has three types of cones sensitive to red, green, and blue light.\ **Importance:** It explains how we perceive a wide range of colors through combinations of these three primary colors. **Opponent-Process Theory** **Definition:** A theory suggesting that color perception is controlled by the activity of opposing neural processes (e.g., red-green, blue-yellow).\ **Importance:** It accounts for color afterimages and some aspects of color vision. **Afterimage** **Definition:** A visual illusion in which an image continues to appear after exposure to the original image has ceased.\ **Importance:** It demonstrates the workings of the opponent-process theory in color vision. **Color Blindness** **Definition:** A genetic condition where individuals cannot perceive certain colors accurately, often due to missing cone types.\ **Importance:** It primarily affects the ability to distinguish between red and green, impacting daily life. **Nearsightedness (Myopia)** **Definition:** A vision condition where distant objects appear blurry while close objects can be seen clearly.\ **Importance:** It occurs when the eye is too long or the cornea is too curved, requiring corrective lenses or surgery. **Farsightedness (Hyperopia)** **Definition:** A vision condition where nearby objects are blurry while distant objects can be seen clearly.\ **Importance:** It results from a shorter eye or flatter cornea, often correctable with glasses. **Visual Cliff Study (Eleanor Gibson and Richard Walk, 1960)** **Definition:** An experiment demonstrating depth perception in infants using a simulated cliff.\ **Importance:** Findings suggested that depth perception is innate, as infants showed reluctance to crawl over the \"cliff.\" **Gestalt Laws of Organization** **Definition:** Principles describing how we perceive visual elements as organized wholes.\ **Importance:** They include concepts like closure, proximity, similarity, and simplicity, which guide perception. **Closure** **Definition:** The tendency to perceive incomplete shapes as complete figures.\ **Importance:** It helps in recognizing objects even when parts are missing. **Proximity** **Definition:** The principle that objects near each other tend to be grouped together.\ **Importance:** It affects how we interpret spatial relationships in visual scenes. **Similarity** **Definition:** The tendency to group similar objects together.\ **Importance:** It aids in identifying patterns and organizing visual information. **Simplicity** **Definition:** The preference for the simplest interpretation of a visual arrangement.\ **Importance:** It guides perception to favor straightforward forms and structures. **Blue Dress/Gold Dress** **Definition:** A viral optical illusion that sparked debate about color perception based on lighting conditions.\ **Importance:** It illustrates subjective differences in color perception and the role of contextual cues. **Laurel vs. Yanni** **Definition:** An auditory illusion where listeners hear either \"Laurel\" or \"Yanni\" based on frequency emphasis.\ **Importance:** It highlights differences in auditory perception and processing. **Charles Limb; Building Musical Muscle TED Talk** **Definition:** A TED Talk by neuroscientist Charles Limb discussing the brain\'s response to music.\ **Importance:** He explores how improvisation and musical creativity activate specific brain regions. **Semantic Specificity** **Definition:** The concept that specific words or phrases activate distinct neural patterns related to their meaning.\ **Importance:** It relates to how language and meaning are processed in the brain. **Hammer, Anvil, Stirrup** **Definition:** The three tiny bones in the middle ear that transmit sound vibrations from the eardrum to the inner ear.\ **Importance:** They amplify sound and are essential for hearing. **Inner Ear** **Definition:** The innermost part of the ear that includes the cochlea and vestibular system.\ **Importance:** It converts sound vibrations into neural signals for the brain. **Cochlea** **Definition:** A spiral-shaped structure in the inner ear that contains the sensory receptors for hearing.\ **Importance:** It plays a key role in converting sound waves into electrical signals. **Basilar Membrane** **Definition:** A membrane in the cochlea that moves in response to sound waves, stimulating hair cells.\ **Importance:** Its movement helps transduce sound into nerve impulses. **Hearing Loss** **Definition:** A partial or total inability to hear.\ **Importance:** It can be caused by various factors, including aging, noise exposure, and genetic conditions. **Sensorineural Hearing Loss** **Definition:** Hearing loss resulting from damage to the inner ear or auditory nerve.\ **Importance:** It is often permanent and can be caused by factors like aging or exposure to loud sounds. **Conduction Hearing Loss** **Definition:** Hearing loss caused by problems in the outer or middle ear that prevent sound from being conducted to the inner ear.\ **Importance:** It may be temporary or correctable with medical intervention. **Sound Shadow** **Definition:** The phenomenon where a sound is perceived to be quieter on one side due to the head blocking sound waves.\ **Importance:** It helps in localizing the source of sounds based on their intensity differences. **Place Theory** **Definition:** A theory that explains pitch perception based on the location of activated hair cells along the cochlea.\ **Importance:** It accounts for how different pitches stimulate different areas of the cochlea. **Frequency Theory** **Definition:** A theory that proposes pitch is determined by the frequency of nerve impulses traveling up the auditory nerve.\ **Importance:** It explains how we perceive low frequencies but is less effective for high-frequency sounds. **Pressure** **Definition:** A tactile sensation detected by mechanoreceptors in the skin.\ **Importance:** It contributes to the perception of texture and touch. **Warmth** **Definition:** A tactile sensation associated with heat detected by thermoreceptors.\ **Importance:** It helps in identifying temperature changes in the environment. **Cold** **Definition:** A tactile sensation associated with coolness detected by thermoreceptors.\ **Importance:** It alerts individuals to potential hazards (e.g., frostbite). **Pain** **Definition:** An unpleasant sensory and emotional experience associated with actual or potential tissue damage.\ **Importance:** It serves as a protective mechanism, alerting individuals to injury. **Nociceptors** **Definition:** Sensory receptors that detect pain stimuli.\ **Importance:** They play a crucial role in the perception of pain and protective responses. **Gustation** **Definition:** The sense of taste, involving the detection of flavor compounds through taste buds.\ **Importance:** It contributes to food preferences and dietary choices. **Flavor** **Definition:** The combination of taste and smell that produces a unique sensory experience when consuming food.\ **Importance:** It enhances the enjoyment of eating and can influence eating habits. **Taste Buds** **Definition:** Sensory organs on the tongue that detect taste stimuli.\ **Importance:** They are responsible for perceiving the five basic tastes: sweet, sour, salty, bitter, and umami. **Five Tastes** **Definition:** The basic categories of taste perception: sweet, sour, salty, bitter, and umami (savory).\ **Importance:** Each taste plays a role in nutrition and dietary preferences. **Olfaction** **Definition:** The sense of smell, involving the detection of airborne chemicals through olfactory receptors.\ **Importance:** It contributes to flavor perception and is closely linked to memory and emotion. **Pheromones** **Definition:** Chemical signals released by an organism that affect the behavior or physiology of others of the same species.\ **Importance:** They play roles in communication, mating, and social behaviors. **Summarizing the Senses** **Definition:** An overview of how the senses (sight, hearing, touch, taste, and smell) contribute to perception and interaction with the environment.\ **Importance:** Understanding sensory systems helps in fields like psychology, marketing, and health. **Optical Illusions** **Definition:** Visual phenomena that trick the brain into perceiving something differently than it actually is.\ **Importance:** They provide insight into the complexities of visual perception. **Three-Pronged Trident** **Definition:** An optical illusion that appears to have three prongs but is perceived as having a different number depending on viewing angles.\ **Importance:** It illustrates how perspective affects visual interpretation. **Mueller-Lyer Illusion** **Definition:** An optical illusion where two lines of equal length appear to be different lengths due to arrow-like ends.\ **Importance:** It demonstrates how context and framing can influence perception. **Why Do We Sleep?** **Definition:** A question addressing the purpose of sleep, which includes restorative processes and memory consolidation.\ **Importance:** Sleep is crucial for physical health, cognitive function, and emotional well-being. **Biological Rhythms** **Definition:** Regular, cyclic patterns of biological activity, including sleep-wake cycles and hormonal fluctuations.\ **Importance:** They regulate physiological processes and are influenced by environmental cues. **Circadian Rhythms** **Definition:** Biological cycles that occur approximately every 24 hours, such as the sleep-wake cycle.\ **Importance:** They synchronize physiological processes with the day-night cycle, influencing sleep, alertness, and metabolism. **Suprachiasmatic Nucleus (SCN)** **Definition:** A group of neurons in the hypothalamus that regulates circadian rhythms.\ **Importance:** It acts as the body\'s master clock, responding to light and dark cycles. **Melatonin** **Definition:** A hormone produced by the pineal gland that regulates sleep-wake cycles.\ **Importance:** It is released in response to darkness, promoting sleepiness. **Owl** **Definition:** A term often used to describe people who naturally stay up late and wake later.\ **Importance:** It highlights individual differences in circadian rhythms and sleep patterns. **Lark** **Definition:** A term used for individuals who wake up early and feel most alert in the morning.\ **Importance:** It reflects the variations in sleep preferences among people. **Sleep Deprivation** **Definition:** The condition resulting from insufficient sleep, affecting cognitive and physical performance.\ **Importance:** Chronic sleep deprivation can lead to serious health issues, including impaired immune function and mood disorders. **Does Everyone Need 8 Hours of Sleep?** **Definition:** A common inquiry regarding the optimal amount of sleep needed for health.\ **Importance:** Sleep needs vary by individual, influenced by age, lifestyle, and health, with some needing more or less than the typical 7-9 hours recommended for adults.