Emulsion Dosage Forms PDF

Dosage Forms | By PierreA. Hanna, esc msc.pho, Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University, Egypt. Disperse systems Emulsions  Introduction Two immiscible liquids, one of which is finely subdivided and uniformly distributed as d...

Dosage Forms | By PierreA. Hanna, esc msc.pho, Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University, Egypt. Disperse systems Emulsions  Introduction Two immiscible liquids, one of which is finely subdivided and uniformly distributed as droplets (the dispersed phase, >0.|um) throughout the other (the dispersion medium or continuous phase). The system is stabilized by the presence of an emulsifying agent.  TYPES OF EMULSION * A: oil-in-water (o/w) * B: water-in-oil (w/0) » C:water-in-oil-in-water (w/o/w) ¢ D: oil-in-water-in-oil o/w/o  Advantage of emulsion * Taste masking e ™ penetration » M efficacy (antiseptics, o/w) » Controlled absorption and penetration * Greater emollient effect (w/0)  Tests for identification of emulsion type 1.Miscibility tests (external phase) 2.Conductivity measurements (Systems with aqueous continuous phases will readily conduct electricity) 3.Staining tests (Water-soluble and oil-soluble dyes are used)  Advantage of emulsion * Small and uniformly sized » Sufficiently homogenous * No creaming or redispersed  Types of emulsifying agent ¢ Non-ionic ¢ Anionic e Cationic  Choice of emulsifying agent » Toxicity and irritancy considerations e hydrophile-lipophile ~ balance (HLB) method Any Questions?