Drugs for Parkinson's Disease PDF

Antihyperlipidemic & Vasodilators - Unit 6 Drugs for Parkinson?s Disease Unit 5 NUR 210/BSL 101  Antihyperlipidemic & Vasodilators - Unit 6 Parkinson?s Disease Chronic neurologic disorder for which there is no cure. Symptoms are managed with medication Imbalance of dopamine...

Antihyperlipidemic & Vasodilators - Unit 6 Drugs for Parkinson?s Disease Unit 5 NUR 210/BSL 101  Antihyperlipidemic & Vasodilators - Unit 6 Parkinson?s Disease Chronic neurologic disorder for which there is no cure. Symptoms are managed with medication Imbalance of dopamine (needed to control movement) ? not enough Imbalance of acetylcholine ? too much Causes degeneration of neurons of the extrapyramidal motor tract Symptoms worsen as the disease progresses  Antihyperlipidemic & Vasodilators - Unit 6 Parkinson?s Disease & Pseudoparkinsonism Signs and Symptoms Signs and Symptoms Pill rolling motion in hands Tremors of the head and neck Rigidity Postural changes Shuffling walk Bradykinesia (slow movement) Lack of facial expression No changes in cognitive level  Antihyperlipidemic & Vasodilators - Unit 6 Parkinson?s Disease Treatments Anticholinergic drugs* Block cholinergic receptors ? see anticholinergic presentation Dopaminergics* Drug converts to dopamine Dopamine agonists Stimulate dopamine receptors MAO-B inhibitors Inhibit MAO-B enzyme that interferes with dopamine COMT inhibitors Inhibit COMT enzyme that inactivates dopamine *The drug classifications you are responsible for knowing  Antihyperlipidemic & Vasodilators - Unit 6 Antiparkinson?s drugs ? Dopaminergic ? Carbidopa and Levodopa Action Levopdopa goes to brain cells to convert to dopamine Carbidopa blocks the conversion peripherally so levodopa can get to the brain Uses Treat the signs and symptoms of Parkinson?s disease. Does not cure Parkinson?s disease  Antihyperlipidemic & Vasodilators - Unit 6 Antiparkinson?s drugs ? Dopaminergic ? Carbidopa and Levodopa Side effects/Adverse reactions GI distress, dry mouth Fatigue, insomnia, dizziness, headache, blurred vision Dark urine Orthostatic hypotension, Palpitations Hypotension Urinary retention Psychosis, severe depression  Antihyperlipidemic & Vasodilators - Unit 6 Antiparkinson?s drugs ? Dopaminergic ? Carbidopa and Levodopa Contraindications Antipsychotics Drug and Food interactions Many! High protein foods decrease absorption  Antihyperlipidemic & Vasodilators - Unit 6 Antiparkinson?s drugs ? Nursing care plan Assessment Vital signs Signs and symptoms of Parkinson?s Medical/medication history  Antihyperlipidemic & Vasodilators - Unit 6 Antiparkinson?s drugs ? Nursing care plan Nursing interventions Monitor vital signs for orthostatic hypotension Administer on empty stomach but may give with low protein food if stomach upset occurs High protein foods delay absorption Monitor for signs and symptoms of Parkinson?s Monitor for suicidal ideation  Antihyperlipidemic & Vasodilators - Unit 6 Antiparkinson?s drugs ? Nursing care plan Teach Take on empty stomach Take at the same times each day Take with low protein foods if stomach upset occurs Do not abruptly discontinue drugs Levodopa may cause harmless discoloration of urine and sweat to brown  Antihyperlipidemic & Vasodilators - Unit 6 Antiparkinson?s drugs ? Nursing care plan Evaluation Improved symptom control client and family understanding of the medications Side effects/Adverse reactions minimized