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Avoid carbamazepine in elderly due to increased risk for inappropriate antidiuretic hormone secretion (SIADH) NDRIs work by inhibiting DA reuptake (increases alertness and motivation) & inhibits NE reuptake (increases energy) Dopamine & norepinephrine are two neurotransmitters affected by ND...

Avoid carbamazepine in elderly due to increased risk for inappropriate antidiuretic hormone secretion (SIADH) NDRIs work by inhibiting DA reuptake (increases alertness and motivation) & inhibits NE reuptake (increases energy) Dopamine & norepinephrine are two neurotransmitters affected by NDRIs Agitation, headache, dry mouth, constipation, weight loss are common side effects of NDRIs Prescribing Pearls of NDRIs The NDRI bupropion (Wellbutrin) can be prescribed to improve alertness, energy, and motivation The NDRI bupropion (Wellbutrin) is not a first-line treatment for anxiety The NDRI bupropion (Wellbutrin)is contraindicated in clients with a hx of seizure disorder When should the NDRI be taken? In the morning NDRI should be discontinued if seizures or anxiety occurs