2024 Unit 1 Biology Extra Notes PDF

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These notes provide an overview of cell organelles, material transport processes, such as simple diffusion, facilitated diffusion, and osmosis, and cellular respiration.

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‭Unit 1 Biology Extra Notes‬ ‭Cell Organelle Structures and Roles‬ ‭.‬ N 1 ‭ ucleus‬‭-‬‭to protect and confine the genetic information‬‭(DNA) of the cell.‬ ‭2.‬ ‭Ribosomes‬‭-‬‭either float freely in the cytoplasm or‬‭are attached to the rough ER. They are‬ ‭the site of assemb...

‭Unit 1 Biology Extra Notes‬ ‭Cell Organelle Structures and Roles‬ ‭.‬ N 1 ‭ ucleus‬‭-‬‭to protect and confine the genetic information‬‭(DNA) of the cell.‬ ‭2.‬ ‭Ribosomes‬‭-‬‭either float freely in the cytoplasm or‬‭are attached to the rough ER. They are‬ ‭the site of assembly of the building blocks to make proteins.‬ ‭3.‬ ‭Chloroplast‬‭–‬‭s ite of photosynthesis where light is‬‭captured, glucose & oxygen are made‬ ‭4.‬ ‭Rough Endoplasmic Reticulum‬‭–‬‭has ribosomes on surface,‬‭synthesises & modifies‬ ‭proteins‬ ‭5.‬ ‭Smooth ER‬‭–‬‭s ite of synthesis of lipids‬ ‭6.‬ ‭Golgi body‬‭-‬‭s ites of protein sorting, packaging,‬‭and modification for use in the cell or‬ ‭export out.‬ ‭7.‬ ‭Mitochondria‬‭-‬‭s ite of aerobic cellular respiration‬‭reaction that produces the ATP.‬ ‭8.‬ ‭Vacuole‬‭-‬‭water and solute storage, also maintains‬‭plant cell structure‬ ‭Phospholipid bilayer‬ ‭Recognise and label structures:‬ ‭ ydrophobic‬‭- repels water, (water hating), non polar‬ H ‭Hydrophilic‬‭- attracts water, (water loving), polar‬ ‭Material Transport Processes‬ ‭Simple Diffusion‬ ‭‬ ‭Where?‬‭Not just membranes‬ ‭‬ ‭Which direction?‬‭Down concentration gradient from‬‭H to L - passive‬ ‭‬ ‭What substances can carry it out?‬‭Uncharged particles‬‭s uch as lipid based‬ ‭s ubstances and gases – hydrophobic only‬ ‭Facilitated Diffusion‬ ‭‬ ‭Where?‬‭Protein carrier in membrane‬ ‭‬ ‭Which direction?‬‭Down concentration gradient from‬‭H to L - passive‬ ‭‬ ‭What substances can carry it out?‬‭Large hydrophilic‬‭s ubstances‬ ‭Osmosis‬ ‭‬ ‭Where?‬‭Phospholipids in membrane‬ ‭‬ ‭Which direction?‬‭Down concentration gradient from‬‭H to L - passive‬ ‭‬ ‭What substances can carry it out?‬‭Water – hydrophilic‬ ‭‬ ‭Definition:‬‭The passive movement of‬‭water‬‭across a‬‭semi-permeable membrane‬ ‭from‬‭an area of‬‭low solute (high water) concentration‬‭to‬‭an area of‬‭high solute‬ ‭(low water) concentration‬‭.‬ ‭Active transport‬ ‭‬ ‭Where?‬‭Protein channel‬ ‭‬ ‭Which direction?‬‭Against concentration gradient from‬‭L to H‬ ‭‬ ‭What substances can carry it out?‬‭Hydrophilic only‬ ‭‬ ‭Definition:‬‭requires‬‭ATP‬‭to move/pump ions (charged‬‭particles) against a‬ ‭concentration gradient from low to high concentration‬ ‭ ypotonic Solution‬‭– water will move towards higher‬‭solute (low water), into cell‬ H ‭Hypertonic Solution‬‭– water moves towards higher solute‬‭(low water), outside cell‬ ‭Isotonic‬‭– equilibrium of solute and solvent between‬‭inside and outside of cell‬ ‭Protein Synthesis‬ ‭‬ N ‭ ucleotide – phosphate, sugar, base (A,C,T,G)‬ ‭‬ ‭Ribosome – site of protein synthesis which occurs on its surface‬ ‭‬ ‭Transcription‬‭- DNA (A,C,T,G) template strand creates single mRNA (A,C,U,G)‬ ‭strand in nucleus using free nucleotides via RNA polymerase enzyme‬ ‭‬ ‭mRNA travels out of nucleus to ribosome‬ ‭‬ ‭Translation‬‭– tRNA brings anticodon with amino acid‬‭to complementary mRNA‬ ‭codon which join together to create a polypeptide chain‬ ‭‬ ‭This amino acid sequence creates a specific Protein‬ ‭‬ ‭Use of genetic code table – know this!‬ ‭Cellular Respiration‬ ‭Mitochondria‬ ‭Part‬ ‭Name‬ ‭1‬ ‭Cristae‬ ‭2‬ ‭Matrix‬ ‭3‬ ‭Inner mitochondrial membrane‬ ‭4‬ ‭Outer mitochondrial membrane‬ ‭ ames of 3 stages, locations and number of ATP gained / Inputs and outputs of each‬ N ‭stage‬ ‭Stage name‬ ‭Location‬ ‭Net ATP gain‬ ‭Aerobic or Anaerobic‬ ‭1. Glycolysis‬ ‭Cytosol‬ ‭2‬ ‭Anaerobic (no O2)‬ ‭.Citric Acid cycle /‬ 2 ‭Matrix‬ ‭2‬ ‭ erobic‬ A ‭Krebs cycle‬ ‭Doesn’t have O‬‭2‬ ‭as in input, but is‬ ‭dependent on O‬‭2‬ ‭.‬‭Electron‬ 3 ‭Cristae‬ ‭26‬ ‭ erobic‬ A ‭Transport chain‬ ‭Literally has‬‭O‭2‬ ‬ ‭as an input.‬ ‭Glycolysis‬ ‭Location‬ ‭Inputs‬ ‭Outputs‬ ‭Cytoplasm‬ ‭ ‬‭6‭H C ‬ ‬‭12‬‭O‭6 ‬ ‬ ‭(glucose)‬ ‭ yruvate‬ P ‭ADP + Pi‬ ‭2 ATP‬ ‭H (from glucose)‬ ‭Kreb’s Cycle‬ ‭Location‬ ‭Inputs‬ ‭Outputs‬ ‭Matrix‬ ‭ yruvate‬ P ‭ O‬‭2‬ C ‭ADP + Pi‬ ‭2 ATP‬ ‭H (from pyruvate)‬ ‭Location‬ ‭Inputs‬ ‭Outputs‬ I‭nner mitochondrial‬ ‭‬ H ‭ 6 ATP‬ 2 ‭membrane / Cristae‬ ‭ADP + Pi‬ ‭H‬‭2‭O ‬ ‬ ‭O‬‭2‬ ‭Electron Transport Chain‬ ‭Photosynthesis‬ ‭Purpose, when and where it occurs‬ ‭Part‬ ‭Name‬ ‭Role in photosynthesis‬ ‭A‬ ‭Grana‬ ‭Absorb light, split water‬ ‭B‬ ‭Stroma‬ ‭Join CO2 and H to form C6H12O6‬ ‭Chloroplast – labelling‬ ‭Inputs and outputs of each stage‬ ‭Stage name‬ ‭Location‬ ‭Inputs‬ ‭Outputs‬ ‭.Light‬ 1 ‭Grana‬ ‭ ight‬ L ‭ ‬ H ‭dependent‬ ‭H‬‭2‭0 ‬ ‬ ‭O‬‭2‬ ‭reactions‬ ‭.Light‬ 2 ‭Stroma‬ ‭ O‬‭2‬ C ‭C‬‭6‭H ‬ ‬‭12‬‭O‬‭6‬ ‭independent‬ ‭H‬ ‭reactions‬ ‭Digestive system‬ ‭Chemical Digestion - Enzymes‬ ‭ ‬ ‭ tomach:‬‭pepsin action, optimal pH 2 and‬‭can withstand acidic (gastric acid)‬ S ‭environment‬ ‭ ‬ ‭Small intestine:‬‭trypsin action, optimal pH 8‬ ‭ mall intestine:‬ S ‭ ‬ ‭Has a long length which contains a specialised surface, that contains millions of tiny‬ ‭folds called‬‭villi,‬‭giving it a large surface area.‬ ‭ ‬ ‭On top of that, the epithelial cells lining the small intestine and its villi contain‬‭microvilli‬ ‭on their exposed surface, increasing the surface area even more.‬ ‭Macromolecules –‬‭are broken down into their monomers‬‭by the enzymes outlined in‬ ‭the table below.‬ ‭Macromolecule‬ ‭Enzyme class required‬ ‭Monomer (absorbable)‬ ‭Protein‬ ‭Protease‬ ‭Amino acid‬ ‭Carbohydrate‬ ‭Amylases‬ ‭Monosaccharide, eg Glucose‬ ‭Nucleic acid‬ ‭Nuclease‬ ‭ ucleotide: nitrogen base and pentose‬ N ‭sugar‬ ‭Plant Structure and Function‬ ‭ eaf structure: shape (surface area to volume), cuticle, mesophyll, stomata‬ L ‭ ‬ ‭Palisade mesophyll‬‭site of‬‭photosynthesis‬‭and is located‬‭on the‬‭upper surface‬‭of the leaf‬ ‭ ‬ ‭Spongy mesophyll‬‭is the main site of‬‭gas exchange‬‭and is ocated on the‬‭lower surface‬‭of leaf‬ ‭ ‬ ‭Stomata‬‭are on the‬‭underside‬‭of the leaf‬ ‭ ‬ ‭The‬‭top surface‬‭of the leaf is covered by a thick,‬‭waxy‬‭cuticle‬‭(‬‭prevents water loss‬ ‭ ‬ ‭Vascular bundles‬‭(including xylem and phloem) are‬‭located centrally to allow for optimal access‬ ‭by all leaf cells‬ ‭ tomata opening and closing:‬ S ‭Guard cells surround stomata and when they fill with water the stomata opens but when‬ ‭water is not available, the guard cells are not filled with water and the stomata close.‬ ‭To close stomata and save water, plants:‬ ‭ ‬ ‭Actively pump potassium ions out of guard cells‬ ‭ ‬ ‭W‭a‬ ter then diffuses out of the vacuoles and guard‬‭cells‬ ‭ ‬ ‭E‭a‬ ch guard cell becomes flaccid, closing the stomata‬ ‭Water Movement‬ ‭ oot structure:‬‭shape (roots hairs: increases surface‬‭area to volume), active transport of‬ R ‭minerals to initiate osmosis of water into root hair‬ ‭Vascular tissues: Xylem and Phloem‬ ‭ ylem:‬‭dead, continuous, one direction, moves water,‬‭cohesion/capillary action (water‬ X ‭molecules sticking together) adhesion is water molecules sticking to sides of the vessel‬ ‭Phloem:‬‭living, companion cells, two directional, moves sugar and minerals‬ ‭Key knowledge‬ ‭From chromosomes to genomes‬ ‭The distinction between genes, alleles and a genome‬ ‭ ene – section of DNA on chromosome‬ G ‭Allele – an alternate form of a gene‬ ‭Genome – full set of DNA/genes in an organism‬ ‭The nature of a pair of homologous chromosomes carrying the same gene loci and the distinction between‬ ‭a utosomes and sex chromosomes‬ ‭ omologous chromosomes – carry same genes at the same gene loci, one for mother, one for father‬ H ‭Autosomes – non sex chromosomes, chromosome pairs 1-22‬ ‭Sex chromosomes – X for female, Y for male‬ ‭The production of haploid gametes from diploid cells by meiosis, including the significance of crossing over‬ ‭of chromatids and independent assortment for genetic diversity‬ ‭ aploid – 23 chromosomes in gametes (sperm and egg cells)‬ H ‭Diploid – full set, 46 in all somatic cells/not gametes‬ ‭Meiosis – 2 divisions. 4 cells produced, crossing over and independent assortment create variation‬ ‭Genotypes and phenotypes‬ T‭ he use of symbols in the writing of genotypes for the alleles present at a particular gene locus –‬‭eg AA‬ ‭The expression of dominant and recessive phenotypes, including‬‭codominance (blood types, A, B, AB, O)‬‭a nd‬ ‭incomplete dominance (RR=Red, rr=White but Rr=Pink)‬ ‭I nfluences of epigenetic factors, on phenotypes‬ ‭Changes in the way the gene is expressed due to alterations in how tightly coiled the DNA is around‬ ‭histones or via DNA methylation‬ ‭Patterns of inheritance‬ ‭Pedigree charts and patterns of inheritance, including autosomal and sex-linked inheritance‬ ‭ ode of‬ M ‭ aulty‬ F ‭ Affected‬ ‭ Healthy‬ ‭.‬ ‭Autosomal dominant –‬ 1 ‭inheritance‬ ‭Allele‬ ‭individuals‬ ‭Individuals‬ ‭look for image on right and the‬ ‭1.‬ A ‭ utosomal‬ ‭trait appearing in every generation‬ ‭Dominant‬ ‭A ‬ ‭AA or Aa ‬ ‭aa‬ ‭2.‬ ‭Autosomal recessive – look‬ ‭for two unaffected parents‬ ‭2.‬ A ‭ utosomal‬ ‭ B or Bb‬ B ‭producing and affected child‬ ‭b ‬ ‭bb‬ ‭Recessive‬ ‭(carrier)‬ ‭3.‬ ‭Sex linked dominant –‬ ‭more in Female, affected faher s‬ ‭3.‬ ‭Sex Linked‬ ‭Female‬ ‭ ale‬ F M ‭ emale‬ M ‭ ale‬ ‭pass on to all daughters, not sons‬ ‭(X)‬ ‭X‭H‬ ‬‭‬ ‭ ‭H‬ ‬‭X‭H‬ ‬ ‭or‬ X ‭H‬ ‭h‬ ‭ ‭H‬ ‭Y X ‬ ‬ ‭ ‭h‬ ‭X X ‬ ‭h‬ ‬ ‭ ‭h‬ ‭Y X ‬ ‬ ‭Dominant‬ ‭X‬ ‭X‬ ‭4.‬ ‭Sex Linked‬ ‭ emale‬ F ‭Female‬ M ‭ ale‬ ‭ ale‬ M ‭(X)‬ ‭X‭r‬ ‭‬ ‬ ‭X‭R‬ ‬‭X‭R‬ ‬‭or‬ ‭X‭r‬‭X ‬ ‭r‬ ‬ ‭ ‭r‬‬‭Y‬ X ‭ ‭R‬ ‬‭Y‬ X ‭Recessive‬ ‭X‭R‬ ‬‭X‭r‬‬ ‭4.‬ ‭Sex linked recessive – more in Males, unaffected carrier females occur‬ ‭Predicted genetic outcomes for a monohybrid cross and a monohybrid test cross‬ ‭Purpose of a test cross – to determine the genotype of a parent displaying the dominant phenotype.‬ ‭‬ ‭How it works: Cross the parent with an organism of known recessive phenotype. A? x aa‬ ‭‬ ‭Possible Outcome 1: If only the dominant phenotype results then the unknown genotype is‬ ‭homozygous dominant. AA x aa = 100% Aa‬ ‭‬ ‭Possible Outcome 2: If dominant and recessive phenotypes result then the unknown‬ ‭phenotype is heterozygous. Aa x aa = 50% Aa and 50% aa‬ ‭****Always write genotype AND phenotype % at the end of the punnet square‬

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