Summary

This document provides a comprehensive overview of different types of tissues in the human body. It discusses connective tissue, including its components and types, as well as various supportive tissues like cartilage and bone. Additional sections explain muscular and nervous tissue, and concludes with a look at epithelial tissue, including descriptions of several subtypes. The document would be suitable as lecture notes detailing tissue types.

Full Transcript

**4.1 Types of Tissues (COOKED 4)** - Connective tissue- binds and supports body parts - Muscular tissue- moves the body and its parts - Nervous tissue-conducts nerve impulses - Epithelial tissue- covers body surfaces; lines body cavities **4.2 Connective Tissue Connects and Support...

**4.1 Types of Tissues (COOKED 4)** - Connective tissue- binds and supports body parts - Muscular tissue- moves the body and its parts - Nervous tissue-conducts nerve impulses - Epithelial tissue- covers body surfaces; lines body cavities **4.2 Connective Tissue Connects and Supports** ***Connective Tissue Components*** - Specialized cells, ground substances, and protein fibers - Ground substance- noncellular material between the cells - Varies in consistency from solid (bone) to fluid (blood) Three types of protein fibers - Collagen fibers- flexible and strong - Reticular fibers- thin, highly branched collagen fibers - Elastic fibers- contain elastin, a protein that stretches and recoils **Fibrous Connective Tissue** - Comes in two main forms: loose and dense - Both contain fibroblasts separated by matrix (ground substance and fibers ***Loose fibrous connective tissue*** - includes areolar connective tissue, reticular connective tissue, and adipose tissue (supports epithelium and many internal organs) ***Dense fibrous connective tissue*** - found in tendons (connect muscles to bones) and ligaments (connect bones to bones) - Contains densely packed collagen fibers ***Adipose tissue (loose)*** - Very little extracellular matrix - Adipocytes- cells filled with liquid fat - Function in energy storage, insulation, and cushioning - Found primarily under the skin and around some organs **Supportive Connective Tissue** - Two major types- cartilage and bone - Functions in structure, shape, protection, and leverage for movement - Cartilage is more flexible than bone because it lacks mineralization of the matrix **Cartilage** - Chondrocytes and chondroblasts- cells that lie in small chambers called lacunae - Matrix is solid but flexible - Lacks a direct blood supply, so heals slowly Three types, distinguished by the type of fiber found in the matrix - Hyaline cartilage- fine collagen fibers (found in the tip of the nose, ends of long bones and the fetal skeleton) - Elastic cartilage- lots of elastic fibers. (found in the outer ear) - Fibrocartilage- strong collagen fibers. (Found in the disks between vertebrae) **Bone** The most rigid connective tissue - Matrix is made of collage and calcium salts - Salts surround protein fibers, which provide elasticity and strength (steel rods in reinforced concrete) - Compact and spongy are types of bone tissue. - Cells called osteoblasts and osteoclasts form the matrix in bone tissue Compact bones make up the shafts of long bones. - Consists of cylindrical structural units called osteons - The central canal contains blood vessels and nerves - Bone cells are in lacunae Spongy bone is inside the end of long bones - Lighter than compact bone, but strong **Fluid Connective Tissue 1** - Two types of fluid connect tissue: blood and lymph ***Blood and lymph*** Cooked 6 covers this Though lymph contains wbcs **4.3 Muscular Tissue Moves the Body** **Muscular Tissue** - Specialized to contract - Cells are called muscle fibers - Skeletal, smooth, and cardiac **Skeletal Muscle** - Attached to the skeleton by tendonds - Contraction moves the skeleton - Voluntarily controlled - Muscle fibers are very long; can run the entire length of the muscle - Have multiple nuclei - Straited, or striped, in appearance **Smooth Muscle** - No striations - Spindle-shaped cells with one nucleus - Involuntarily controlled - Found in the walls of viscera **Cardiac Muscle** - Found only in the walls of the heart - Striated - Involuntarily controlled - Single nucleus - Cells are connected by intercalated disks **4.4 Nervous Tissue Communicates** **Nervous Tissue** - Consists of neurons and neuroglia - Sensory input, integration, and motor output. **Neurons** - Dendrites, a cell body, and an axon - Dendrites carry the information toward the cell body - The cell body contains the nucleus and other organelles - Axon conducts nerve impulses away from the cell body - Some axons are covered in myelin, a fatty substance Nerves- bundles of axons traveling to and from the brain and spinal cord **Neuroglia** - Outnumber neurons 9 to 1 - Take up more than half the volume of the brain - Main function is to support and nourish neurons **4.5 Epithelial Tissue Protects** - Made of tightly packed cells - Lines body cavities, covers body surfaces, and is found in glands - Anchored by a basement membrane on one side and is free on the other side - Named for the number of cell layers and the shape of the cells - Simple vs stratified; squamous, columnar, or cuboidal **Simple epithelia** ***Simple squamous epithelium*** - Single layer of flattened cells - That is, found in the lungs, where it functions in gas exchange ***Simple cuboidal epithelium*** - Single layer of cube-shaped cells ***Simple columnar epithelium*** - Single layer of column-shaped cells ***Pseudostratified columnar epithelium*** - Because of the location of the nuclei, it appears stratified but every cell touches the basement membrane - Often has cilia, which moves mucus across its surface ***Gland*** - One or more cells that make and secrete a product - Two types: exocrine and endocrine - Exocrine glands secrete into ducts - Endocrine glands secrete into blood stream; have no ducts **Stratified Epithelia** - Several layers of cells ***Stratified Squamous epithelia*** - Forms the outer layer of the skin and lines the mouth, esophagus ***Transitional epithelia*** - Cells change shape in response to tension (cuboidal to squamous) - Found lining in the urinary bladder **4.6 Organ Systems, Body Cavities, and Body Membranes** Organs and cavities are lined with membranes, many of which secrete fluid **Anatomical Terms** - Ventral or anterior refers to the front - Dorsal or posterior means toward the back - Superior means toward the head - Inferior means toward the feet Some are relative to other body parts - Something that is medial is closer to the midline of the body - Lateral, away from the midline When referring to an appendage like an arm or a leg - Proximal means closer to the trunk of the body - Distal means away from the trunk **Organ Systems** - Some organs are involved in the function of more than one organ system - For example, the pancreas plays a role in the endocrine and digestive systems - Other structures and glands also contribute to the operation of organ systems **Body Cavities** - Two main cavities: dorsal and ventral ***Ventral cavity (coelom in early development)*** - Contains the thoracic, abdominal, and pelvic cavities - The diaphragm separates the thoracic and abdominal cavities - The thoracic cavity contains the lungs and the heart - The abdominal cavity contains the stomach, liver, spleen, pancreas, gallbladder, and most of the small and large intestines - The pelvic cavity contains the rectum, the urinary bladder, the internal reproductive organs, and the rest of the small and large intestines - Males have an external extension of the abdominal wall called the scrotum, which contains the testes ***Dorsal cavity*** - Contains the cranial cavity and vertebral canal **Body Membranes** - Line cavities and the internal spaces of organs and tubes that open to the outside - Four types: mucous, serous, and synovial membranes and the meninges ***Mucous membranes*** - Line the tubes of the digestive, respiratory, urinary, and reproductive systems - Composed of epithelium overlying loose fibrous connective tissue - Contains goblet cells that secrete mucus ***Serous membranes*** - Line closed cavities (not open to the environment) and cover the surface of the organs contained within - That is, pleurae line the thoracic cavity and cover the lungs - That is, pericardium forms the pericardial sac and covers the heart - That is, double layer of peritoneum, called mesentery, lines the abdominal cavity and covers its organs ***Synovial Membranes*** - Composed only of loose connective tissue - Line freely moveable joints - Secrete synovial fluid for lubrication ***Meninges*** - Composed only of connective tissue - In the dorsal cavity (protects the brain and spinal cord) - Meningitis- inflammation of the meninges **4.7 Integumentary System** - Includes skin and accessory organs such as hair, nails, and glands Functions: - Protects underlying tissue from trauma, pathogen invasion, and water loss - Helps regulate body temp - Contains sensory receptors, such as touch and temp receptors - Makes us aware of our surroundings Contains all 4 tissue types - Skin has two main regions: the epidermis and the dermis - Under the skin there is a subcutaneous layer (hypodermis) - The subcutaneous layer is between the skin and underlying structures, such as muscle or bone **Epidermis** - Thin, outermost layer of the skin - Stratified squamous epithelium - Stem cells that produce new epidermal cells are in the deepest layer - If an injury destroys the stem cells, skin needs to be replaced - Autograft- from another area of the body - Allograft- from another person ***Cells of the Epidermis*** Keratinocytes- in the upper layers of epidermis - Dead and filled with keratin - Forms a waterproof barrier Langerhans cells - A type of white blood cell Melanocytes - Product melanin - Produces skin color and protects from UV light - People have the same number of melanocytes, but the amount of melanin produced varies Other contributors to skin color: carotene and hemoglobin - Epidermal cells produce vitamin D when exposed to UV rays - Vitamin D is important in the regulation of calcium and phosphorus levels in the body **Skin cancer** - Caused by ultraviolet rays from the sun ***Basal cell carcinoma*** - Cancer of epidermal stem cells - Most common type of skin cancer; easily curable ***Melanoma*** - Cancer of melanocytes - Extremely serious **The Dermis** - Thick, inner layer of the skin - Made of dense fibrous connective tissue - Contains collagen and elastic fibers for strength and elasticity - Contains blood vessels, sensory receptors, and glands - Sensory receptors are specialized for touch, pressure, pain, heat, and cold **The Subcutaneous Layer** - Technically not part of the skin - Composed of loose connective tissue and adipose tissue - Stores energy, insulates, and protects **Accessory Organs of the Skin** ***Nails*** - Nails offer a protective covering of the digits (fingers and toes) - Nails grow from the nail root to cover the nail bed - The cuticle covers the nail root - Lunula- white half moon shape at the base ***Hair*** - Hair follicles- epidermal structures that surround the hair itself - Hair shaft- the portion of hair protruding from the skin - The color of hair comes from melanin; as melanocytes age, they produce less pigment and hair turns gray - Arrector pili muscles- attached to the hair follicle - Can contract, which creates goosebumps ***Oil Glands (sebaceous glands)*** - Produce sebum, which softens the hair and skin - Also retards bacterial growth - Acne-inflammation of the sebaceous glands ***Sweat glands (sudoriferous glands)*** - In the dermis, their ducts open onto the skin surface - Help to regulate body temperature **4.8 Homeostasis** - Relatively constant internal environment - Blood glucose, ph, body temp - If conditions vary too much, illness results **The Internal Environment** - Blood and interstitial fluid - Blood delivers oxygen and nutrients to the tissues and carries away co2 and waste - Interstitial fluid surrounds body cells: substances are exchanged through it - Body systems work together to keep these substances within the range or normalcy **Body Systems and Homeostasis** The nervous and endocrine systems coordinate the other organ systems - The nervous system is faster, but the effects of the endocrine system last longer - The Endocrine system secretes hormones-chemical messengers that travel in blood **Negative Feedback** - The primary mechanism used in the body - Two components: a sensor and control center - The output of the system turns down, or off, the production - That is, how a furnace works - Temperature regulation **Positive Feedback** - Brings about a change in the same direction as the original stimulus - Childbirth: the fetus's head pushes against the cervix, which stimulates signals that are sent to the brain - The brain then secretes the hormone oxytocin, which causes stronger contractions - This causes more oxytocin to be released - Childbirth stops the positive feedback - Can be harmful in some situations (fever)

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