Over The Counter Drugs and Children's Sensitivity
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This document provides information on over-the-counter medications, herbal supplements, and considerations for different age groups, especially children. It discusses how drug metabolism and response vary between adults and children, stressing the importance of caution when administering medications to children.
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**Over the counter drug:** -antihistamines: cetirizine (Zyrtec), dyphenhidramine (Benadryl), loratadine (Claritin) -eyedrops: artificial tears -pain relieve: acetaminophen, ibuprofen, aspirin -nasal steroids: fluticasone **Herbal and dietary supplement:** -cranberry: decreases elimination of r...
**Over the counter drug:** -antihistamines: cetirizine (Zyrtec), dyphenhidramine (Benadryl), loratadine (Claritin) -eyedrops: artificial tears -pain relieve: acetaminophen, ibuprofen, aspirin -nasal steroids: fluticasone **Herbal and dietary supplement:** -cranberry: decreases elimination of renally excreted drug -garlic: interference with decreased blood glucose therapy -gingko: increase risk for bleeding with anticoagulants, antiplatelets -grapefruit: decrease metabolism of some drugs, increase duration of caffeine effects -St. John's wort: lead to serotonin syndrome if taken with other serotonergic drugs **Life span:** \ intensive effect of drugs -BBB not fully improved -drug metabolism is low -renal secretion is low **Children:** -absorption, distribution, excretion: more like adults -metabolism: faster than adults DON'T give aspirin to children -\> Reye's syndrome -\> can be fatal Glucocorticoids -\> can suppress inflammation -\> try not to use for children because it can suppress their growth -\> try to use small dose, short time
