Pediatric and Geriatric Considerations PDF

Document Details

PeaceableGreen

Uploaded by PeaceableGreen

University of Northern British Columbia

Tags

immunology pediatric immunity geriatric immunity biology

Summary

This document discusses pediatric and geriatric immunity. Pediatric immunity benefits from maternal antibodies initially, while geriatric immunity shows decreased T-cell activity and antibody response.

Full Transcript

Pediatric and Geriatric Considerations Pediatric Immunity Sufficient IgM but deficient IgG & IgA responses Maternal antibodies provide protection within the fetal circulation and during the first months of life Geriatric Immunity Decreased T-cell activity (Thymus size is 15% of its maximum size) Th...

Pediatric and Geriatric Considerations Pediatric Immunity Sufficient IgM but deficient IgG & IgA responses Maternal antibodies provide protection within the fetal circulation and during the first months of life Geriatric Immunity Decreased T-cell activity (Thymus size is 15% of its maximum size) Thymic hormone production drops, as does the organ’s ability to mediate T-cell differentiation Decreased antibody response to antigens

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