Capillaria philippinensis PDF

Capillaria philippinensis Dr/ Ayman Abdelmaogod Lecturer of medical parasitology Disease: intestinal capillariasis Geographical distribution: the disease is endemic in Philippines, Thailand and some areas of Far East. Some cases are diagnosed in Egypt Morphology: female size- 2.3- 5.3mm...

Capillaria philippinensis Dr/ Ayman Abdelmaogod Lecturer of medical parasitology Disease: intestinal capillariasis Geographical distribution: the disease is endemic in Philippines, Thailand and some areas of Far East. Some cases are diagnosed in Egypt Morphology: female size- 2.3- 5.3mm in length(oviparous-larviparous)uterus can contain eggs&larvae male - 2- 4mm in length Eggs: Size: 20x 40u Shape: peanut- shaped and bioperculated with thick shell Colour: golden yellow Content: immature Life cycle: The adult worms lives embedded in the mucosa of the jejunum and ileum of the D.h( fish eating birds and occasionally man) The female lay thick shelled eggs or larvaefaeces The eggs mature in fresh water in 5- 10 days eaten by small fresh water fish(I.h)hatch in their intestine, burrow in the mucosaadult Mode of human infection: ingestion of the whole raw fish where the infective larvae are located in the mucosa of the fish intestine Internal autoinfection: the larvae released by the larviparous female mature, matelays eggs& larvae which develop into adults and so on causing hyperinfection. Pathogenesis&clinical picture The worms causes epithelial erosion of the mucosa of the small intestine mainly the jejunumchronic inflammationmalabsorptionloss of the fluids,electrolytes and plasma proteins leading to : Abdominal pain,severe watery diarrhoea,nausea,vomiting,weight loss,generalized oedema and hypotention the disease is fatal if not treated diagnosis Clinically Laboratory: Direct: Stool examination to find eggs, larvae and adults. Charcot leyden crystal may be found Indirect diagnosis: I D test using capillaria antigen. Eosinophilia Marked hypoproteinaemia especially albumin Electrolyte depletion(Na,K,Cl, calcium,Mg) especially K treatment Mebendazole: 400mg daily for one month Albendazole: 400mg daily for 10 days Electrolyte replacement by iv fluids High protein diet Prevention&control Avoid eating raw fish Sanitary disposal of human excreta Mass treatment Health education Best wishes