Pharmacology Made Easy: Biologic DMARDs - etanercept PDF - ATI
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Uploaded by DignifiedRadon
Royal Holloway, University of London
2023
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Summary
This document from Assessment Technologies Institute (ATI) provides a medication information table for Biologic DMARDs, specifically etanercept. It covers therapeutic uses, adverse drug reactions, interventions, administration instructions, client instructions and contraindications, with focus on pharmacology and drug interactions. This is a useful resource for healthcare professionals.
Full Transcript
Pharmacology Made Easy Medication Information Table Biologic DMARDs – etanercept Category Information THERAPEUTIC USE DMARDs are medications that treat and decrease...
Pharmacology Made Easy Medication Information Table Biologic DMARDs – etanercept Category Information THERAPEUTIC USE DMARDs are medications that treat and decrease joint inflammation, and subsequently prevent joint damage. Biologic DMARDs are tumor necrosis factor antagonists—medications that bind with naturally occurring tumor necrosis factor, preventing it from attaching to cells on the surface of synovial tissue in the joints. ADVERSE DRUG Increased susceptibility to infections REACTIONS Dizziness Abdominal pain Pharyngitis Psoriasis Upper Respiratory Infections Rare occurrence of severe allergic reactions such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and erythema multiforme Local injection site reaction Heart failure Reactivation of latent tuberculosis (TB) INTERVENTIONS Assess for infection prior to each injection. Monitor for manifestations of infection during therapy. Monitor for skin reactions. Monitor for discoloration, warmth, and itching at the injection site. Monitor clients for signs and manifestations of heart failure (cough, shortness of breath, elevated blood pressure and heart rate, pink sputum). Administer TB test prior to starting therapy ADMINISTRATION Administer by subcutaneous injection. Give once weekly Monitor site for redness, pain, and swelling after administration. CLIENT INSTRUCTIONS Report signs and manifestations of infection immediately. Avoid immunizations, especially those that contain live vaccines. Report skin rashes immediately. Advise clients to report reactions that do not subside within a few days. Report manifestations of heart failure (cough, shortness of breath, elevated blood pressure and heart rate, pink sputum) immediately. Report shortness of breath or new production of sputum. Copyright ©2023 Assessment Technologies Institute, L.L.C. All rights reserved. This resource is copyright protected material of ATI and is provided for use solely under license by ATI. Copying, distributing, or posting this material on the internet or social media is strictly prohibited. Posting on institution LMS requires ATI’s prior written permission. PAGE 1 www.atitesting.com ©2023 Assessment Technologies Institute, L.L.C. Pharmacology Made Easy: Medication Information Table Biologic DMARDs – etanercept Category Information CONTRAINDICATIONS Active infection Hematologic disease Malignancy PRECAUTIONS Autoimmune diseases Live vaccines Heart failure INTERACTIONS Administration with chemotherapeutic medications may cause bone marrow suppression. Should not be given with anakinra due to increased risk of infections. Live vaccines PAGE 2 www.atitesting.com ©2023 Assessment Technologies Institute, L.L.C.
