Allosteric Modifiers (Inhibitors and Activators) PDF
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Uploaded by SpeedyBarbizonSchool
Tanta University Faculty of Medicine
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Summary
This document explains allosteric inhibitors and activators. It describes how these small organic molecules can bind to enzymes outside of their active site to potentially decrease or increase activity. The document includes an example of ATP as an allosteric modifiers
Full Transcript
- Allosteric modifiers (inhibitors and activators) Allosteric inhibitors: They are usually small organic molecules that bind to a specific site away from the catalytic site and produce conformational changes in protein structure that lead to decreased activity of the enzyme Example : ATP for phospho...
- Allosteric modifiers (inhibitors and activators) Allosteric inhibitors: They are usually small organic molecules that bind to a specific site away from the catalytic site and produce conformational changes in protein structure that lead to decreased activity of the enzyme Example : ATP for phosphofructokinase-1 - Allosteric modifiers (inhibitors and activators) 1