Temperature Pathophysiology PDF
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Uploaded by OutstandingSimile
Samuel Merritt University
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Summary
This document discusses temperature regulation, aging effects on temperature regulation, fever, hyperthermia, and hypothermia. It provides a lecture outline or presentation on these topics, including detailed information on the mechanisms related to these processes. The document appears to be intended for a pathophysiology course at Samuel Merritt University.
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TEMPERATURE N111 Pathophysiology Samuel Merritt University TEMPERATURE REGULATION Peripheral & central thermoreceptors hypothalamic control Heat production and conservation Chemical reactions to metabolism Skeletal muscle contraction Voluntary mechanisms ...
TEMPERATURE N111 Pathophysiology Samuel Merritt University TEMPERATURE REGULATION Peripheral & central thermoreceptors hypothalamic control Heat production and conservation Chemical reactions to metabolism Skeletal muscle contraction Voluntary mechanisms AGING Slowed blood circulation, vasoconstriction, and decreased metabolic rate sweating, shivering, and perception of cold and heat TEMPERATURE PATHOPHYSIOLOGY FEVER E: Pyrogens (exogenous and endogenous) P: Resets the hypothalamic thermostat to a higher temperature or set point Activates heat production and conservation of heat until the new set point is reached TI: Tylenol? FEVER (CONT’D) FEVER BENEFITS Kills the invading microorganisms Promotes lysosomal breakdown and autodestruction of infected cells lymphocytic transformation & phagocytic motility Augments antiviral interferon production Augments phagocytosis HYPERTHERMIA NO resetting the set point or mediation by Pyrogens Heat cramps, exhaustion, heatstroke 41° (105.8°) nerve damage convulsions 43° (109.4°) death HYPOTHERMIA
