Irritable Bowel Syndrome (IBS) PDF

Irritable Bowel Syndrome (IBS) Prof. Dr. Wesam Ahmed Ibrahim Professor of Internal Medicine gu.edu.eg What is irritable bowel syndrome (IBS)? Irritable bowel syndrome (IBS) is a group of symptoms that affect your digestive system. It’s a common....

Irritable Bowel Syndrome (IBS) Prof. Dr. Wesam Ahmed Ibrahim Professor of Internal Medicine gu.edu.eg What is irritable bowel syndrome (IBS)? Irritable bowel syndrome (IBS) is a group of symptoms that affect your digestive system. It’s a common. People with IBS experience symptoms that include abdominal pain and cramps. With IBS, you may also have frequent diarrhea, constipation or both. IBS doesn’t cause tissue damage in your GI (gastrointestinal) tract or increase risk of more serious conditions, like colon cancer. Instead, it’s a chronic (long-term) condition that most people can manage by changing their routines and what they eat, taking medications and receiving behavioral therapy.  Subtypes of IBS IBS-D (diarrhea predominant( IBS-C (constipation predominant) IBS-M (mixed diarrhea and constipation) IBS-U (unclassified; the symptoms cannot be categorized into one of the above three subtypes) What are the types of IBS? Researchers categorize IBS based on how stools look on the days when you’re having symptom. Most people with IBS have normal bowel movements on some days and abnormal ones on others. The abnormal days define the kind of IBS you have. IBS with constipation (IBS-C): Most of stool is hard and lumpy. IBS with diarrhea (IBS-D): Most of stool is loose and watery. IBS with mixed bowel habits (IBS-M): both hard and lumpy bowel movements and loose and watery movements. IBS-U (unclassified; the symptoms The differences are important. Certain treatments only work for specific types of IBS. How common is IBS? It’s very common. Experts estimate that about 10% to 15% of adults in the United States have IBS. Only about 5% to 7% see a provider and receive a diagnosis. It’s the most common disease that gastroenterologists diagnose. What are the symptoms of IBS? Symptoms of IBS can appear frequently. Or, they may occur during flare-ups. In other words, you don’t always experience symptoms. Instead, symptoms may go away (and you’ll have normal bowel movements). At other times, symptoms return. Signs and symptoms of IBS include: Abdominal pain or cramps, usually related to the urge to poop. Excess gas and bloating. Diarrhea, constipation or alternating between the two. Mucus in your poop (may look whitish). Feeling like you’re unable to empty your bowels after pooping. Pathophysiology What causes IBS? Researchers don’t know exactly what causes IBS, but they classify it as a neurogastrointestinal (GI) disorder. These conditions, also called disorders of the gut-brain interaction, have to do with problems with how your gut and brain coordinate to help your digestive system work. Communication challenges between your brain and gut can cause: Dysmotility: You may have problems with how your GI muscles contract and move food through your GI tract. The colon (large intestine) muscle tends to contract more in people with IBS. These contractions cause cramps and pain. Visceral hypersensitivity: You may have extra-sensitive nerves in your GI tract. People with IBS tend to have a lower pain tolerance than people without it. Your digestive tract may be super sensitive to abdominal pain or discomfort. Other potential causes of IBS include: Gut bacteria: Research has shown that people with IBS may have altered bacteria in their GI tract, contributing to symptoms. Studies have shown that the types and amounts of gut bacteria are different in people with IBS than in people without it. Severe infections: Some people get diagnosed with IBS after a severe infection affecting their GI tract, suggesting germs may play a role. Food intolerance: Sensitivities or allergies to certain foods may contribute to IBS. Childhood stress: IBS is more common in people who experienced severe stressors in childhood, including physical, sexual and emotional abuse. IBS triggers: If you have IBS, you may have noticed that certain things trigger symptoms. A trigger doesn’t cause the condition itself, but it can cause or worsen a symptom flare-up. Common triggers include: Periods: People assigned female at birth (AFAB) may notice symptoms worsen predictability according to their menstrual cycle. Certain foods: Food triggers vary from person to person. Still, common culprits that can trigger an IBS symptom flare-up include dairy, foods that contain gluten (like wheat) and foods/drinks known to make you gassy. Stress: Some researchers suggest that IBS is your gut’s response to stress. Related, this is why IBS is sometimes called “nervous stomach” or “anxious stomach.” Risk factors for IBS: ü IBS most often occurs in people in their late teens to early 40s. ü female are up to twice as likely to get diagnosed with IBS. Other risk factors include: Intolerance to certain foods. Severe digestive tract infection. History of abuse. Diagnosis of anxiety, depression or post-traumatic stress disorder (PTSD). Many people with IBS also have other chronic pain conditions. Conditions associated with an increased risk of IBS include: Fibromyalgia. Chronic fatigue syndrome. Chronic pelvic pain. Diagnosis and Tests How is IBS diagnosed? The first step in diagnosing IBS is a detailed medical history. Your provider will ask about symptoms. They may ask: Do you have pain related to bowel movements? Do you notice a change in how often you have a bowel movement? Has there been a change in how your poop looks? How often do you have symptoms? When did your symptoms start? What medicines do you take? Have you been sick or had a stressful event in your life recently? Depending on your symptoms, you may need other tests to confirm a diagnosis. There isn’t a single test to diagnose IBS. Instead, your provider will determine if you have IBS by: Asking about your symptoms. Making sure you’re up to date on your colon cancer screening. Checking that you don’t have symptoms suggesting other disorders. Lab tests: Most lab tests exclude other conditions that may be causing your symptoms, like an infection, food intolerance or a different digestive condition, like inflammatory bowel disease (IBD). Not everyone needs the same tests. Blood test: To check for a digestive disease condition or another condition that may cause your symptoms. Stool test: To check for an infection or signs of inflammation in your bowel caused by a digestive condition. Hydrogen breath test: To see if you have an overgrowth of bacteria in your gut (SIBO) or a food intolerance. Imaging tests: You may need imaging procedures to rule out conditions involving inflammation or abnormal growths in your GI tract. Colonoscopy: Can help your provider determine if you have certain bowel disorders that may be causing your symptoms, including polyps, IBD and cancerous growths. Flexible sigmoidoscopy Upper endoscopy: Can help your provider diagnose celiac disease or other GI conditions. What is the treatment for IBS? No specific therapy works for everyone, but most people with IBS can find a treatment plan that works for them. Typical treatment options include changing the foods you eat and your routine. Medications can help, too. Behavioral health therapy may help. Many of these treatments take time to work. They can help your symptoms, but your symptoms may not go away completely. Meal changes: A dietitian can help you choose foods and modify eating/drinking habits to avoid symptom flare- ups. They may recommend that you: Increase fiber in your diet. Fiber-rich foods, including fruits, vegetables, grains, prunes and nuts, can help if you’re struggling with constipation. Introduce fiber slowly into your diet to give your gut time to adjust. Add supplemental fiber to your diet. Limit dairy products, like cheese and milk. Lactose intolerance is more common in people with IBS. If you cut back on dairy, make sure to eat nondairy foods rich in calcium, like broccoli, spinach or salmon. Meal changes: Limit foods that can make you gassy. Foods like beans and cabbage are notorious for causing gas, but carbonated sodas and even chewing gum can make you gassy. Reduce these foods to go easier on your gut. Avoid gluten. People with IBS — even those without celiac disease — tend to be more sensitive to gluten. If you opt for a gluten-free diet, work with your provider to ensure you’re getting enough of the key vitamins and minerals (like fiber, iron and calcium) often found in foods with gluten. Try the low FODMAP diet. This food plan reduces the amount of hard-to-digest carbohydrates you eat. It recommends alternatives that allow you to get the nutrients you need while going easier on your GI tract. Meal changes: Drink plenty of water. Drink at least eight 8-ounce glasses of water a day (2 liters). Water keeps your GI tract lubricated and can help treat or prevent constipation. Keep a food diary. Your provider may recommend that you note the foods you eat to determine which foods trigger IBS flare-ups and then bring this to a nutritionist. Activity changes: Changing daily activities can help, too. Your provider may recommend that you: Exercise regularly. Aim for 150 minutes of moderate exercise weekly. This is about 30 minutes a day, five days a week. “Moderate” means you’re raising your heart rate. Try relaxation techniques. Daily yoga, meditation and other de-stressing techniques can help calm an overtaxed nervous system and a “nervous gut.” Sometimes, a behavioral therapist can help. Get enough sleep. Aim for seven to nine hours of quality sleep each night. Go to bed at the same time each night. A good night’s rest is one of the most powerful de-stressors available. Reach out to a provider if you’re having trouble sleeping. Keep an activity diary. Record the activities that help you manage your IBS and compare notes with your provider. Medications Your healthcare provider may prescribe medications to provide symptom relief, including: Antidepressants (if you have depression and anxiety along with significant abdominal pain). Medications to ease constipation (including fiber supplements and laxatives). Medications to firm stools (anti-diarrheals). Medications to help with intestinal spasms. Although research into their effectiveness is ongoing, your provider may recommend probiotics. These “good bacteria” may help relieve IBS symptoms. Thank You gu.edu.eg