Pharmacology L1 Mcqs PDF

Pharmacology L1 Mcqs 1|Page 1) A macrolide antibiotic is required to treat a streptococcal infection in a 71-year-old penicillin-sensitive man who is also receiving digoxin and warfarin therapy. Which of the following drugs would be best for this patient? A. Erythromycin...

Pharmacology L1 Mcqs 1|Page 1) A macrolide antibiotic is required to treat a streptococcal infection in a 71-year-old penicillin-sensitive man who is also receiving digoxin and warfarin therapy. Which of the following drugs would be best for this patient? A. Erythromycin B. Azithromycin C. Clarithromycin D. Telithromycin E. None of the above 2) Select the fourth generation cephalosporin among the following: A. Cefuroxime B. Ceftazidime C. Cefepime D. Ceftizoxime E. None of the above 3) Vancomycin has the following unwanted effects.......... A. Pseudomembranous colitis B. Hepatotoxicity C. Red neck" syndrome, phlebitis D. All of the above 4) Patient of bronchial asthma maintained on theophylline developed upper respiratory tract infection. Which antimicrobial if used can increase the risk of developing theophylline toxicity: A. Ampicillin. B. Cephalexin. C. Cotrimoxazole. D. Erythromycin. 5) Clavulanic acid is combined with amoxicillin because......... A. It counteracts the adverse effects of amoxicillin B. It inhibits beta lactamases that destroy amoxicillin C. It retards renal excretion of amoxicillin D. It kills bacteria that are not killed by amoxicillin E. None of the above 6) Which of the following antibiotics requires close monitoring and dosing adjustment in this patient given his liver disease? A. Penicillin G. B. Tobramycin. C. Erythromycin D. Vancomycin. 2|Page 7) Patient of deep vein thrombosis maintained on anticoagulant warfarin developed upper respiratory tract infection. Which antimicrobial if used can increase the risk of developing warfarin toxicity: A. Ampicillin B. Cephalexin. C. Erythromycin D. Cotrimoxazole 8) Nour El-Dein is a patient suffering from depression. He takes medications (anti depression) that help him to increase serotonin levels to regulate the mod Nour. After that, he suffered from a bacterial infection, and the pharmacist prescribed for him linezolid Which of the following could may occur? A. Superinfection B. Red man syndrome C. Serotonin syndrome D. Thrombosis 9) In patient of nephrotoxicity can use gentamicin and cefepime: A. This statement is true B. This statement is false 10) Which of the following can use to treatment Clostridium difficele....... A. Ceftazidiem B. Vancomycin IV C. Clindamycin D. Vancomycin Oral 11) Which of the following can used with Pseudomonal infection? A. Ampicillin and it's additional B. Amoxicillin and it's additional C. Pipraceillin and it's additional D. Benzathine penicillin and it's additional 12) Which of the following drug used for MRSA....... A. Penicillin B. Methicillin C. Pipraceillin D. Cefterlion 13) Ceftriaxone are: A. Can't treatment Cholecystitis B. Elimination by kidney. C. Can't cross BBB D. Elimination by kidney and biliary 3|Page 14) Ceftazidiem are: A. Long acting antibiotics B. Specific used with G + C. Short acting antibiotics D. Can't cross BBB 15) Ampicillin can bass normal (healthy BBB): A. This statement is true B. This statement is false 16) Cefazeloin......... A. Active against Gram + & cross BBB B. Active against Gram + & not cross BBB C. Active against Gram- & cross BBB D. Active against Gram- & not cross BBB 17) Which of the following side effects of penicillin? A. Ca deficiency B. Arthritis C. Loos motions D. Red man syndrome 18) Penicillin can kill normal Flora and cause oral contraceptive failure: A. This statement is false B. This statement is true 19) Ampicillin can kill normal Flora and cause oral contraceptive failure: A. This statement is true B. This statement is false 20) Carditis that caused by Rheumatic fever during attack treated by: A. Benzathine penicillin B. Corticosteroids C. Penicillin G D. Cefterlion E. Ceftriaxone 21) Carditis that caused by Rheumatic fever treated by: A. Corticosteroids B. Oral Ampicillin C. Oral Amoxicillin D. IV Ampicillin 4|Page 22) The best use of benzathine penicillin in........ A. Empirical treatment B. Prophylaxis C. With MRSA but not VRSA D. With MRSA and VRSA 23) Which of the following drug are B lactamase sensitive? A. Amoxicillin B. Ceftriaxone C. Cefepime D. Ceftazidiem E. None of the above 24) Penicillin V are: A. Long acting & parental B. Long acting & oral C. Short acting & oral D. Long acting & oral 25) Benzyl penicillin are: A. Long acting & parental B. Short acting & oral C. Long acting & oral D. Short acting & parental 26) Which of the following drug are bacteriostatic? A. Pipraceillin B. Cefotaxime C. Cefepime D. Cefterlion E. Rifamycin 27) The antibiotics drug are taking without any combination to give best effect: A. This statement is true B. This statement is false 28) Which one of the following antimicrobial drugs inhibits bacterial cell wall synthesis? A. Tetracycline B. Piperacillin C. Ciprofloxacin D. Gentamycin E. Erythromycin 5|Page 29) Which of the following drug inhibition of bacterial cell wall synthesis? A. Quinolones B. Sulfonamides C. Gentamicin D. Carpenem E. Erythromycin 30) Mohamed Salah is a child suffering from a bacterial infection that caused him many problems. He went to the pharmacy. The pharmacist prescribed Penicillin V for him as he done a culture but also the treatment didn't produce results. After a while, the result of the analysis turned out to be MRSA. He went to the doctor and the doctor prescribed Vancomycin for him and he should take it for a certain period, but Mohamed didn't. He didn't complete his course, and unfortunately the problem came back again. The doctor here repeated the treatment again, but he did not get the result of doing another culture. It turned out that the bacteria had become resistant to Vancomycin. Which of the following medicines useful for Muhammad's condition? A. Cefterlion B. Ampicillin with clavulnic acid C. Ceftriaxone D. Linezolid E. Ceftazidiem 31) One of the following is not true of linezolid: A. inhibits bacterial protein synthesis at an early step. B. It is active against vancomycin resistant enterococci C. It is the drug of choice for enterococcal endocarditis D. It can be administered orally as well as by i.v. infusion. 32) Cefotaxime ……… A. Active against Gram -ve & cross BBB B. Active against Gram +ve & not cross BBB C. Active against Gram -ve & not cross BBB D. Active against Gram +ve & cross BBB 33) Which one of the following antibiotics acts mainly against gram negative bacteria? A. Benzathine penicillin B. Erythromycin C. Cefotaxime D. Vancomycin E. Penicillin G 6|Page Answers 1 B 2 C 3 C 4 D 5 B 6 C 7 C 8 C 9 B 10 D 11 C 12 D 13 D 14 C 15 B 16 B 17 C 18 B 19 A 20 B 21 D 22 B 23 A 24 C 25 D 26 A 27 B 28 B 29 D 30 D 31 C 32 A 33 C 34 35 36 37 38 39 40 41 42 7|Page