Pediatric Hemoptysis PDF - September 6th, 2022

Pediatric Hemoptysis Dr. Salah Abdulkareem Ibrahim M.B.Ch.B. F.K.B.M.S. College of medicine/University of Dohuk [email protected] September 6th, 2022 General Presentation u Hemoptysis, defined as coughing up blood or present...

Pediatric Hemoptysis Dr. Salah Abdulkareem Ibrahim M.B.Ch.B. F.K.B.M.S. College of medicine/University of Dohuk [email protected] September 6th, 2022 General Presentation u Hemoptysis, defined as coughing up blood or presenting with blood in sputum, arises from the lungs. There are two vascular beds that supply the 7 lungs: the pulmonary arterial circulatory system which is a low pressure system, and the bronchial circulatory system which is a high pressure system. Hemoptysis can occur when either of these vascular beds is damaged. Massive hemoptysis, usually suggesting damage in the high pressure bronchial vasculature, is defined as the - presence of more than 8 mL/kg of blood over 24. hours for adults day 600 Ml / ( 75 Ky ) General Presentation/cont u Hemoptysis is rarely seen in children, especially in children younger than 6 years of age because they tend to swallow their sputum. When evaluating a child presenting with expectoration of blood, it is important to determine the origin of the bleeding, as blood may have come from extrapulmonary sites such as the upper airway or from the gastrointestinal system (hematemesis). This differentiation is important as it alters the investigation and treatment plans. Hemoptysis is characterized by bright red blood that may be frothy with an alkaline pH. Comparison between hemoptysis and hematemesis ☆ Features Hemoptysis Hematemesis Sputum features -bright red or pink - dark red or brown if frothy -pH: alkaline - lower in GI tract, consistency: liquid bright red if higher with clotted look - up -usually not frothy content: mixed in -pH: acidic - with sputum consistency: ground coffee, stale blood appearance -content: may have food particles History no nausea or presence of nausea vomiting -may have or vomiting -may history of lung have history of disease -may be gastrointestinal or associated with hepatic disease coughing or gurgling u History of Chief Complaint: - Seek information regarding the timing and amount of blood (when did it occur, has it been constant, how much blood is expelled each time) - Find out about associated symptoms: u fever? Is there a recent history of infection or cold symptoms (fatigue, runny nose, sore throat, coughing)? Have there been recent choking episodes? Has there been recent weight loss or appetite changes? Is the child short of breath? Is the child paler than usual or cyanotic (this can point to an underlying cardiac or vasculature problem) Is there any pain, either localized or generalized? (this can help determine the location of bleeding) - Inquire about any episodes of recent trauma or the possibility of aspiration - Inquire about any medications that the child has or may have taken - Inquire about travel history and infectious contacts u Past Medical History - Any complications in the perinatal or neonatal period? - Does the child have any known underlying diseases (eg. Cystic Fibrosis, Ciliary dyskinesia, congenital diseases, rheumatic heart disease). - Is there a history of symptoms that may suggest chronic lung disease (eg. long-term coughing, wheezing, or stridor) - Are there any surgeries that the child has undergone? - Is the child’s growth and development progressing normally?  u Are there any familial disorders? - bleeding → tendency Are there any allergies the child → eosinophilia & hyper IgE makes thin has? - Are the child’s vaccinations the vessel Predispose to rupture up to date? - What do they think is § the cause of hemoptysis? Do you want ↳ this to add anything , ( Did I miss anything ) ? BCG to question change your entire approach may protect against TB Physical Examination u A complete general physical exam that includes vitals (blood pressure, heart rate, respiratory rate and temperature) and growth parameters must be carried out. u Inspection: you should observe the patient’s body habitus and distress level. Look for any signs of blunt trauma such as bruising or swelling. Observe chest wall expansion during a breath to assess for symmetry or indications of a collapsed lung. Observe the skin colour for paleness or cyanosis. u Palpation: you will want to palpate the chest area for any signs of tenderness or masses. Feel for any swollen lymph nodes. Tactile fremitus and percussion: you will want to assess the right and left lungs for tenderness or any signs of consolidation (dullness to percussion), collapse, or effusion. u Auscultation: Ensure to ascultate the 3 lobes of the right lung and 2 lobes of the left lung. Listen for abnormal breath sounds including localized wheezing (foreign bodies), pleural rubs (pneumonia), bruits or thrills (arteriovenous malformation), and any heart murmurs (suggests cardiac origin). Differential Diagnosis u A. Infectious causes: 40% of hemoptysis is due to acute lower respiratory tract infections u a. Pneumonia i. Bacteria (eg. pneumococcal) u ii.Virus (eg. Respiratory syncytial virus) u iii. Fungus (eg. aspergillosis) u iv. Parasitic (eg. echinococcosis) u b. Lung abscess u c. Tracheobronchitis u d. Immunodeficiency e. g SCID u B. Trauma u a. Aspiration of foreign body (major cause of hemoptysis for children younger than 4 years of age) Toodler G. ☒ ja u b. Contusion u c. Iatrogenic (eg. damage from bronchoscopy) u C. Bronchiectasis u a. Cystic fibrosis u b. Ciliary dyskinesia u c. post-lower respiratory tract infection u D. Vasculature u a. Pulmonary arteriovenous malformation u b. Alveolar hemorrhage syndromes (eg. associated with renal disease or rheumatologic disease) u c. Connective tissue disease (eg. Goodpasture syndrome, vasculitis) u d. Pulmonary thromboembolism u E. Neoplasms (uncommon) u a. Bronchial adenoma 1° , less likely u b. Metastatic cancer 2°, more likely Investigations u A) Laboratory tests u -CBC and differential (to assess infectious causes, hemoglobin level) u –ESR (may be elevated in infection and systemic disease) u -D-dimer (if pulmonary embolism is suggested) u -Coagulation studies (INR, PTT) (to rule out coagulation disorders) u -sputum sample sent in for C&S for bacteria, fungus, and mycobacteria infection u B) Diagnostic imaging -Chest X-ray: In many cases of hemoptysis, a plain chest X-ray is insufficient to identify the location of bleeding. As many as a third of children presenting with hemoptysis will have normal chest x-rays. An abnormal x-ray, however, can be useful in showing atelectasis, pneumothorax, alveolar infiltrates or some neoplastic tumours.  CT u Chest computed tomography: Should a chest X-ray be insufficient, a chest CT would be the next procedure of choice. A chest CT is useful for further visualization of the lung parenchyma and associated vasculature. u -MRI: An MRI may be helpful in evaluating the mediastinum and hilum structures, as well as finding arteriovenous malformations, but is not always readily available and usually requires sedation in the pediatric population. u -Bronchoscopy: If laboratory and imaging investigations are insufficient in determining the location and cause of hemoptysis, flexible fiberoptic bronchoscopy is indicated.  treat the cause symptomatic Rxcmucotgt:c)