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This document describes the anatomy and related procedures for the male and female urethra. It covers the different parts and components of the urethra and associated techniques like catheterization, ureteroscopy, and biopsies.
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+-----------------+-----------------+-----------------+-----------------+ | **Male | \- Elastic tube | | | | Urethra** | from neck of | | | | | bladder to the | | | | **...
+-----------------+-----------------+-----------------+-----------------+ | **Male | \- Elastic tube | | | | Urethra** | from neck of | | | | | bladder to the | | | | **Anatomy** | tip of glans | | | | | penis | | | | | | | | | | **[3 | | | | | Parts]{.underli | | | | | ne}** | | | | | | | | | | **[Prostatic | | | | | (pars | | | | | prostatica)]{.u | | | | | nderline}** | | | | | | | | | | \- The part of | | | | | urethra passing | | | | | through | | | | | prostate. | | | | | | | | | | \- Elevation in | | | | | middle | | | | | (colliculus | | | | | seminalis), has | | | | | depression | | | | | called | | | | | utriculus | | | | | masculinus, on | | | | | either side of | | | | | which are the | | | | | ejaculatory | | | | | ducts. | | | | | | | | | | **[Membranous | | | | | (pars | | | | | membranacea)]{. | | | | | underline}** | | | | | | | | | | \- The part of | | | | | urethra passing | | | | | through pelvic | | | | | floor. | | | | | | | | | | \- Surrounded | | | | | by external | | | | | sphincter | | | | | muscle. | | | | | | | | | | \- | | | | | Bulbourethral | | | | | glands (cow's | | | | | glands) open | | | | | into bulbar | | | | | urethra, to | | | | | lubricate it | | | | | before | | | | | ejaculation. | | | | | | | | | | **[Cavernous | | | | | (pars | | | | | cavernosa)]{.un | | | | | derline}** | | | | | | | | | | \- Divided into | | | | | bulbourethral | | | | | and penile | | | | | urethra | | | +=================+=================+=================+=================+ | **Histology** | **[Prostatic | **[Membranous | **[Cavernous | | | (pars | ]** | (pars | | | prostatica)]{.u | | cavernosa)]{.un | | | nderline}** | **[(pars | derline}** | | | | membranacea)]{. | | | | \- Transitional | underline}** | \- Squamous | | | epithelium | | cell epithelium | | | | \- | | | | | Pseudostratifie | | | | | d | | | | | columnar | | | | | epithelium | | +-----------------+-----------------+-----------------+-----------------+ | **Female | \- External | | | | Urethra** | opening of | | | | | female urethra | | | | **Anatomy** | is 2cm below | | | | | clitoris | | | | | | | | | | **[Skene | | | | | Glands]{.underl | | | | | ine}** | | | | | | | | | | \- Paraurethral | | | | | glands or | | | | | female | | | | | prostate, are a | | | | | pair of glands | | | | | located on | | | | | either side of | | | | | the female | | | | | urethra. | | | | | | | | | | **[Urethra | | | | | Mucosa]{.underl | | | | | ine}** | | | | | | | | | | \- This lining | | | | | helps the | | | | | urethra | | | | | accommodate the | | | | | passage of | | | | | urine and | | | | | prevents | | | | | leakage between | | | | | voids. | | | | | Additionally, | | | | | the surrounding | | | | | musculature, | | | | | including the | | | | | external | | | | | urethral | | | | | sphincter, | | | | | provides | | | | | voluntary | | | | | control over | | | | | the release of | | | | | urine. | | | +-----------------+-----------------+-----------------+-----------------+ | **French | **[French | | | | Catheter | Catheter | | | | Scale** | Scale]{.underli | | | | | ne}** | | | | | | | | | | \- System used | | | | | to measure the | | | | | outer diameter | | | | | of catheters | | | | | and other | | | | | medical tubing. | | | | | | | | | | 1 FR=3/uX(pi) | | | +-----------------+-----------------+-----------------+-----------------+ | **Urethrocystos | **[Indications] | | | | copy** | ** | | | | | | | | | | \- Hematuria, | | | | | suspected | | | | | bladder | | | | | carcinoma, | | | | | control of | | | | | resection of | | | | | bladder | | | | | carcinoma, | | | | | overview of | | | | | urethra, | | | | | cystitis, | | | | | urinary | | | | | incontinence, | | | | | bladder | | | | | fistula, | | | | | strictures of | | | | | urethra, BPH, | | | | | foreign body in | | | | | urethra or | | | | | bladder. | | | | | | | | | | **[Contraindica | | | | | tions]{.underli | | | | | ne}** | | | | | | | | | | \- Acute | | | | | urinary tract | | | | | infection | | | | | (prostatitis, | | | | | urethritis, | | | | | epididymorchiti | | | | | s) | | | | | | | | | | \- Septic | | | | | conditions | | | | | | | | | | **[Technique]{. | | | | | underline}** | | | | | | | | | | \- Anaesthesia | | | | | (local, venous, | | | | | spinal) | | | | | | | | | | \- Lubrication | | | | | to reduce | | | | | mucosal trauma | | | | | | | | | | \- French | | | | | catheter scale | | | +-----------------+-----------------+-----------------+-----------------+ | **Resectoscope* | \- Similar to | | | | * | cystoscope but | | | | | with capability | | | | | to perform | | | | | resection using | | | | | electrical | | | | | current | | | | | | | | | | **[Indication]{ | | | | |.underline}** | | | | | | | | | | \- Benign | | | | | prostate | | | | | hyperplasia | | | | | (BPH) | | | | | | | | | | \- Bladder | | | | | carcinoma, | | | | | | | | | | \- Ureterocoele | | | +-----------------+-----------------+-----------------+-----------------+ | **Urethrotomes* | \- Surgical | | | | * | instruments | | | | | designed | | | | | typically | | | | | consists of a | | | | | narrow, sharp | | | | | blade or | | | | | cutting element | | | | | that can be | | | | | introduced into | | | | | the urethra to | | | | | make precise | | | | | incisions in | | | | | the strictured | | | | | area. | | | | | | | | | | \- The | | | | | procedure is | | | | | often done | | | | | under local or | | | | | general | | | | | anaesthesia. | | | | | | | | | | \- For the | | | | | treatment of | | | | | urethral | | | | | strictures. A | | | | | urethral | | | | | stricture is a | | | | | narrowing of | | | | | the urethra | | | +-----------------+-----------------+-----------------+-----------------+ | **Ureteroscopy* | Similar to | **[Contraindica | | | * | cystoscopy but | tions]{.underli | | | | longer (45cm -- | ne}** | | | | 55cm in length) | | | | | | \- Inflammatory | | | | **[Indications] | processes | | | | ** | | | | | | \- Narrow | | | | \- Bleeding | ureters | | | | from upper | | | | | urinary tract | \- Severe | | | | | strictures of | | | | \- Stones in | ureter | | | | upper urinary | **[Types]{.unde | | | | tract | rline}** | | | | | | | | | \- Tumours in | \- Semi-rigid | | | | upper urinary | | | | | tract | \- Flexible | | | | | | | | | \- Strictures | | | | | in ureter | | | | | | | | | | \- Extraction | | | | | of foreign | | | | | bodies in upper | | | | | urinary tract | | | +-----------------+-----------------+-----------------+-----------------+ | **Nephroscopes* | **[Rigid | | | | * | Nephroscope]{.u | | | | | nderline}** | | | | | | | | | | \- Antegrade | | | | | manipulations | | | | | | | | | | \- for | | | | | visualizing and | | | | | treating larger | | | | | kidney stones. | | | | | They provide a | | | | | clear and | | | | | direct view of | | | | | the kidney\'s | | | | | interior, | | | | | allowing | | | | | urologists to | | | | | fragment and | | | | | remove stone. | | | | | | | | | | **[Flexible | | | | | Nephroscope | | | | | ]** | | | | | | | | | | \- Antegrade | | | | | manipulations | | | | | | | | | | \- Particularly | | | | | useful for | | | | | accessing | | | | | calyces and | | | | | smaller spaces | | | | | within the | | | | | kidney | | | +-----------------+-----------------+-----------------+-----------------+ | **Sources of | **[Resection]{. | | | | Energy** | underline}** | | | | | | | | | | \- Monopolar | | | | | single | | | | | electrode for | | | | | cutting and | | | | | coagulation | | | | | | | | | | \- Bipolar | | | | | minimizing the | | | | | risk of injury | | | | | to surrounding | | | | | tissues | | | | | | | | | | **[Lithotripsy] | | | | | ** | | | | | | | | | | \- Ultrasound | | | | | | | | | | \- Lasers | | | | | | | | | | **[Tissue | | | | | Vaporisation | | | | | ]** | | | | | | | | | | \- Lasers | | | +-----------------+-----------------+-----------------+-----------------+ | **Biopsy** | **[Ultrasound | **[Bladder | | | | Guided | Biopsy]{.underl | | | | Biopsy]{.underl | ine}** | | | | ine}** | | | | | | [Indications]{. | | | | [Indications]{. | underline} | | | | underline} | | | | | | \- Interstitial | | | | \- Small | cystitis | | | | tumours (no | | | | | treatment | \- Malakoplakia | | | | required) | | | | | | \- Bladder | | | | \- Inoperable | carcinoma | | | | large tumours | | | | | | [Technique]{.un | | | | **[Prostate | derline} | | | | Biopsy]{.underl | | | | | ine}** | \- | | | | | Endoscopically | | | | [Indication]{.u | (cystoscope or | | | | nderline} | resectoscope) | | | | | | | | | \- Cancer | \- With clip or | | | | suspected | resection loop | | | | | | | | | \- Elevated PSA | **[Testicular | | | | | Biopsy]{.underl | | | | \- Abnormal | ine}** | | | | digital rectal | | | | | exam [ | [Indication]{.u | | | | ] | nderline} | | | | | | | | | [Technique]{.un | \- Testicular | | | | derline} | tumour | | | | | | | | | \- Transrectal | \- Male | | | | | infertility | | | | \- | | | | | Transperineal | [Technique]{.un | | | | | derline} | | | | [Complications] | | | | | | \- | | | | | Contralateral | | | | \- Pain | testes also | | | | | screened (high | | | | \- Bleeding | risk of spread) | | | | | | | | | \- Prostatitis | \- Open biopsy | | | | | (with incision | | | | | instead of | | | | | needle) | | | | | | | | | | [Obstructive | | | | | Azoospermia | | | | | ] | | | | | | | | | | \- Mature | | | | | spermatozoa | | | | | detected | | | | | | | | | | [Non-obstructiv | | | | | e | | | | | Azoospermia]{.u | | | | | nderline} | | | | | | | | | | \- No | | | | | spermatozoa | | | | | detected (no | | | | | spermatogenesis | | | | | ) | | +-----------------+-----------------+-----------------+-----------------+ | **Lymph Nodes** | \- Lymph nodes | | | | | indicate stage | | | | | of cancer | | | | | progression. | | | | | | | | | | **[Kidney | | | | | Carcinoma]{.und | | | | | erline}** | | | | | | | | | | \- | | | | | Retroperitoneal | | | | | lymph nodes | | | | | | | | | | **[Testicular | | | | | Carcinoma]{.und | | | | | erline}** | | | | | | | | | | \- | | | | | Retroperitoneal | | | | | lymph nodes | | | | | | | | | | **[Prostate | | | | | Carcinoma]{.und | | | | | erline}** | | | | | | | | | | \- Pelvic lymph | | | | | nodes | | | | | | | | | | **[Bladder | | | | | Carcinoma]{.und | | | | | erline}** | | | | | | | | | | \- Pelvic lymph | | | | | nodes | | | | | | | | | | **[Penile | | | | | Carcinoma]{.und | | | | | erline}** | | | | | | | | | | \- Inguinal | | | | | lymph nodes | | | +-----------------+-----------------+-----------------+-----------------+ | **Lower urinary | **[Vesicostomy] | | | | tract | ** | | | | drainage** | | | | | | \- Involves | | | | | creating an | | | | | opening in the | | | | | bladder that is | | | | | brought to the | | | | | surface of the | | | | | abdomen. | | | | | | | | | | \- A catheter | | | | | is then | | | | | inserted into | | | | | this opening to | | | | | allow urine to | | | | | drain directly | | | | | from the | | | | | bladder to the | | | | | outside. | | | | | | | | | | **[Suprapubic | | | | | Drainage]{.unde | | | | | rline}** | | | | | | | | | | \- Catheter is | | | | | inserted | | | | | through the | | | | | abdominal wall | | | | | directly into | | | | | the bladder. | | | | | | | | | | \- This is | | | | | typically done | | | | | by making a | | | | | small incision | | | | | above the pubic | | | | | bone. | | | +-----------------+-----------------+-----------------+-----------------+ | **Bladder | **[Diagnostic | **[Ballon | | | Catheterization | ]** | Inflation | | | ** | | Catheter]{.unde | | | | \- Monitor | rline}** | | | | hourly diuresis | | | | | | \- Inflation | | | | \- Taking urine | limitations | | | | for | marked on | | | | microbiological | catheter | | | | examination in | | | | | women | \- In adults | | | | | 5ml-15ml | | | | \- Injecting | maximum | | | | drugs | | | | | (cystatics) or | \- Saline | | | | contrast agents | solution or 10% | | | | (cystography) | glycerine | | | | | solution is | | | | **[Therapeutics | used for | | | | ]** | silicone | | | | | catheters | | | | \- Relieve | | | | | acute urine | **[Catheter | | | | retention | material]{.unde | | | | | rline}** | | | | \- Irrigation | | | | | of bladder | \- Latex | | | | | | | | | **[Patient | \- Silicone | | | | Preparation]{.u | (more suitable | | | | nderline}** | for mucosa) | | | | | | | | | \- Cleaning of | **[Catheter | | | | genital with | size]{.underlin | | | | antiseptic | e}** | | | | solution | | | | | | \- Children | | | | \- Anaesthesia | (6-10) | | | | using sterile | | | | | gels containing | \- Adults | | | | lidocaine (wait | (12-16) | | | | 3 minutes) | | | | | | | | | | \- Lubrication | | | | | to reduce risk | | | | | of urethral | | | | | trauma | | | +-----------------+-----------------+-----------------+-----------------+ | **Suprapubic | \- Catheter is | **[Advantages]{ | | | Drainage of | inserted |.underline}** | | | Urine** | through the | | | | | abdominal wall | \- Patient | | | | directly into | comfort (local | | | | the bladder. | anaesthesia) | | | | This is | | | | | typically done | \- Reduced risk | | | | by making a | of urinary | | | | small incision | tract infection | | | | above the pubic | | | | | bone. | \- Absence of | | | | | strictures | | | | **[Indications] | | | | | ** | **[Disadvantage | | | | | s]* | | | | \- Impossible | * | | | | transurethral | | | | | bladder | \- Need for | | | | catheterization | hospitalization | | | | | | | | | \- Traumatic | \- Risk of | | | | urethral injury | perforation of | | | | | intestinal loop | | | | \- Neurogenic | or bleeding | | | | bladder damage | | | | | [ ] | \- Leakage of | | | | | urine around | | | | **[Technique]{. | catheter during | | | | underline}** | detrusor | | | | | contractions | | | | \- Under | | | | | ultrasound | | | | | control | | | +-----------------+-----------------+-----------------+-----------------+ | **Upper Urinary | **[Nephrostomy] | **[Ureteral | | | Tract Drainage | ** | Stent (Double J | | | Methods** | | Stent)]{.underl | | | | Tube carrying | ine}** | | | | urine drainage | | | | | from kidney | \- The ureter | | | | allows urine to | is the tube | | | | bypass the | that connects | | | | obstruction and | the kidney to | | | | flow directly | the bladder, | | | | from the kidney | allowing urine | | | | to an external | to pass from | | | | drainage bag. | the kidney to | | | | | the bladder. | | | | [Risk and | | | | | Complications]{ | [Indication]{.u | | | |.underline} | nderline} | | | | | | | | | \- Infection | \- | | | | | Hydronephrosis | | | | \- Bleeding | | | | | | [Complications] | | | | \- Accidental | | | | | removal of tube | | | | | | \- Iatrogenic | | | | | injuries | | +-----------------+-----------------+-----------------+-----------------+ | **Condom | Condom | | | | Catheter** | connected to | | | | | drainage tube. | | | | | | | | | | [Disadvantages] | | | | | | | | | | | | | | | \- High | | | | | infection risk | | | | | | | | | | \- Allergy to | | | | | material | | | | | | | | | | Compression or | | | | | squeezing of | | | | | penis | | | +-----------------+-----------------+-----------------+-----------------+ | **Prostate | **[Prostate | **[Prostate | | | Tumour | specific | Cancer Antigen | | | Markers** | Antigen]{.under | 3 | | | | line}** | (PCA-3)]{.under | | | | | line}** | | | | \- Organ | | | | | specific but | \- Gene that | | | | not tumour | expresses | | | | specific | non-coding RNA | | | | | only present in | | | | \- Function is | human prostate. | | | | to liquify | | | | | semen | \- Screening | | | | | performed after | | | | \- Half-life: | negative | | | | 14 days | biopsy, before | | | | | deciding to | | | | \- Consistent | perform | | | | elevation 5+ | repeated | | | | days = likely | biopsy. | | | | metastasis | | | | | | \- Located in | | | | [Increased]{.un | urine | | | | derline} | | | | | | **[Rectal | | | | \- Carcinoma of | Douche]{.underl | | | | prostate | ine}** | | | | | | | | | \- Benign | \- A medical | | | | prostatic | procedure | | | | hyperplasia | involving the | | | | | introduction of | | | | \- Prostatitis | a liquid into | | | | | the rectum and | | | | [Decreased]{.un | colon via the | | | | derline} | anus for | | | | | cleaning. | | | | \- | | | | | Transurethral | \- Then first | | | | resection of | urine is tested | | | | prostate | for PCA-3 | | | | | | | | | \- Prostate | \- | | | | removal | | | | | | | | | | \- 5 Alpha | | | | | reductase | | | | | inhibitors | | | +-----------------+-----------------+-----------------+-----------------+