Human Genetics Asynchronous Study Guide PDF

In partnership with Human Genetics BSc (Hons) Dental Hygiene BSc (Hons) Dental Therapy Asynchronous Study Guide MODULE: Biomedical Science HED_4_001  Human Genetics: Asynchronous Study Guide Guide description: This document is a brief guide to assist self-directed learning for the unit...

In partnership with Human Genetics BSc (Hons) Dental Hygiene BSc (Hons) Dental Therapy Asynchronous Study Guide MODULE: Biomedical Science HED_4_001  Human Genetics: Asynchronous Study Guide Guide description: This document is a brief guide to assist self-directed learning for the unit. Minimum suggested time for this unit: 1.5 hours Expectation: Student should review prior knowledge regarding genetic principles, vocabulary and terminology associated with this subject from Basic Biology. Aim: This unit aim to give a brief introduction to human genetics and its relevance in dentistry Learning outcome: After this session, students should be able to – 1. Describe basic principles of human genetics 2. Identify the impact of gene mutation in humans 3. Recognise the relevance of human genetics in dentistry Student Activities: Essential: 1. Pre-session reading: check reading list and/or download available pdf 2. Self- assessment on knowledge related to human genetics: common vocabulary, terminology and principles of genetics in human 3. View pre-recorded video presentation 4. Moodle activity 1 (Formative Assessment section): Share one foreseeable challenge in providing oral health care for a patient with Treacher Collins or Down Syndrome in the group discussion forum. See guided learning from post-session reading. 5. Moodle activity 2 (Formative Assessment section): e-MCQ self-assessment (Quiz) Activities Minimum suggested time 1&2 25 minutes 3 40 minutes 4 15 minutes 5 10 minutes Education Curator: J Khaw Page 1 of 2 BioMedSci  Human Genetics: Asynchronous Study Guide Reading list: Pre-session reading: 1. Waugh, A. and Grant, A. (2018) Chapter 17: Introduction to genetics. Ross & Wilson Anatomy And Physiology In Health And Illness. 13 th Ed. Edinburgh: Elsevier, pp. 475-486. 2. Hart, P.S. and Hart, T.C. (2016) Invited commentary: The need for human genetics and genomics in dental school curricula. Mol Genet Genomic Med, 4, pp. 123-125. DOI: 10.1002/mgg3.216 Guided post-session reading: Campos, P., Taitson, P., da Silva, L. and Leao, L. (2022) Dental and health aspects in the co-occurrence of Treacher Collins and Down syndromes: Case report. Spec Care Dentist, pp. 1-5. DOI: 10.1111/scd.12735 Think about the following questions while you read the above article: i. What were the aetiology of the genetic condition? ii. What were the impact of the gene variant on the patient’s physical development? iii. What are the challenges you can foresee, as a dental hygienist and dental therapist, providing a follow-up oral health care for this patient post- GA treatment? Self Assessment: Vocabulary and Terminology to be familiar Autosomal Translation Adenine Dominant Mutation Guanine Recessive Somatic Cytosine X-linked Gonadal Thymine Imprinting Gamete Replication Microdeletion Radiation Deletion Chromosomes Genes mRNA Chromatin RNA splicing Transcription Mendelian Mitosis Congenital DNA Meiosis disorder Nucleotides Allele Recombinant Double helix Genotype Insertion Amino Acid Phenotype Gene sequencing Student activity in Moodle under Formative Assessment section: 1. Share one foreseeable challenge in providing oral health care for a patient with Treacher Collins or Down Syndrome in the group discussion forum 2. Complete quiz to test your knowledge on this topic Education Curator: J Khaw Page 2 of 2 BioMedSci