Which type of intermolecular interaction would most enhance the water solubility of a medication?
Understand the Problem
The question asks which type of intermolecular interaction would best improve a medication's ability to dissolve in water. We need to consider which intermolecular force is most compatible with water's properties to enhance solubility.
Answer
Dipole-dipole interactions enhance water solubility of a medication.
Dipole-dipole interactions enhance the water solubility of a medication. These interactions happen when there is unequal sharing of electrons in a covalent bond due to differences in electronegativity between the atoms.
Answer for screen readers
Dipole-dipole interactions enhance the water solubility of a medication. These interactions happen when there is unequal sharing of electrons in a covalent bond due to differences in electronegativity between the atoms.
More Information
Water is a polar solvent. Solutes that can participate in dipole-dipole interactions are more likely to dissolve in water. The other types of intermolecular forces are: hydrogen bonding, dispersion forces, and ion-dipole forces.
Tips
A common mistake is to think only about hydrogen bonding and not consider dipole-dipole interactions. Remember to consider all types of intermolecular forces and polarity when it comes to solubility.
Sources
- Drug Solubility - an overview | ScienceDirect Topics - sciencedirect.com
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