Which of the following is the most appropriate treatment? A. Celecoxib B. Ibuprofen C. Tramadol D. Prednisone
Understand the Problem
The question provides a clinical scenario of a 75-year-old man suffering from knee pain and asks for the most appropriate treatment based on the medical history and lab results provided.
Answer
Celecoxib
The final answer is Celecoxib.
Answer for screen readers
The final answer is Celecoxib.
More Information
Given the patient's chronic kidney disease, NSAIDs like ibuprofen may worsen his kidney function further. Celecoxib, a COX-2 inhibitor, poses a lesser risk to kidneys and is effective in managing osteoarthritis pain, as shown in knee osteoarthritis cases.
Tips
A common mistake is assuming all NSAIDs pose the same risk for kidney impairment. COX-2 inhibitors like Celecoxib are typically safer for patients with kidney issues.
Sources
- WHO Analgesic Ladder - StatPearls - ncbi.nlm.nih.gov
- Pharmacologic Therapy for Acute Pain - AAFP - aafp.org
- Comparative Analgesic Effects of Ibuprofen, Celecoxib and... - thejcdp.com
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