Which of the following cellular changes is LEAST likely to be observed in necrotic cells? A) DNA fragmentation as a result of endonuclease activation. B) Increased eosinophilia of... Which of the following cellular changes is LEAST likely to be observed in necrotic cells? A) DNA fragmentation as a result of endonuclease activation. B) Increased eosinophilia of the cytoplasm due to loss of RNA. C) Genetic activation D) Cellular swelling due to failure of the sodium-potassium pump.
Understand the Problem
The question is asking to identify the cellular change least likely to be observed in necrotic cells. Necrosis is a form of cell injury which results in the premature death of cells in living tissue by autolysis. We need to select the incorrect option from the list.
Answer
The answer is C) Genetic Activation because necrosis doesn't typically involve activating new genes.
The cellular change LEAST likely to be observed in necrotic cells is genetic activation. Necrosis is characterized by cellular changes, including DNA fragmentation, increased eosinophilia of the cytoplasm, and cellular swelling.
Answer for screen readers
The cellular change LEAST likely to be observed in necrotic cells is genetic activation. Necrosis is characterized by cellular changes, including DNA fragmentation, increased eosinophilia of the cytoplasm, and cellular swelling.
More Information
Necrosis is a form of cell injury which results in the premature death of cells in living tissue by autolysis. Necrosis is caused by factors external to the cell or tissue, such as infection, toxins, or trauma.
Tips
It is important to remember the key features that define necrosis, particularly when distinguishing it from other forms of cell death like apoptosis.
Sources
- Mechanisms and Morphology of Cellular Injury, Adaptation, and Death - pmc.ncbi.nlm.nih.gov
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