Which adhesion factor is primarily responsible for the initial attachment of a pathogen to host cells?
Understand the Problem
The question is asking which specific adhesion factor is mainly responsible for the initial interaction and attachment of a pathogen to the cells of a host organism. It provides multiple-choice answers relating to microbial structures.
Answer
Pili (fimbriae).
Pili (fimbriae) are primarily responsible for the initial attachment of a pathogen to host cells.
Answer for screen readers
Pili (fimbriae) are primarily responsible for the initial attachment of a pathogen to host cells.
More Information
Pili or fimbriae are hair-like appendages on certain bacteria that facilitate attachment to host cells, aiding in colonization and infection. They are critical in the initial phase of pathogenic invasion.
Tips
A common mistake is confusing different types of adhesins, as other structures like flagella, while involved in motility, do not primarily mediate initial attachment.
Sources
- Bacterial Pathogenesis - Medical Microbiology - NCBI Bookshelf - ncbi.nlm.nih.gov
- Bacterial Adhesion and Entry into Host Cells - ScienceDirect.com - sciencedirect.com
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