What is true regarding the mechanism of action of daptomycin?
Understand the Problem
The question asks about the mechanism of action of the lipopeptide antibiotic daptomycin, specifically how it inhibits bacterial growth and function. The user needs to identify the correct mechanism from the multiple-choice options provided.
Answer
Daptomycin disrupts bacterial cell membrane function, leading to cell death.
Daptomycin's mechanism of action involves calcium-dependent binding to the bacterial membrane, leading to membrane depolarization and disruption of cell membrane function, inhibiting protein, DNA, and RNA synthesis, and ultimately causing bacterial cell death.
Answer for screen readers
Daptomycin's mechanism of action involves calcium-dependent binding to the bacterial membrane, leading to membrane depolarization and disruption of cell membrane function, inhibiting protein, DNA, and RNA synthesis, and ultimately causing bacterial cell death.
More Information
Daptomycin is a cyclic lipopeptide antibiotic used to treat infections caused by Gram-positive bacteria. Its unique mechanism of action makes it effective against drug-resistant strains.
Tips
The exact downstream effects of daptomycin are not fully understood.
Sources
- Daptomycin - StatPearls - NCBI Bookshelf - ncbi.nlm.nih.gov
- Mechanism of Action and Resistance to Daptomycin in ... - pmc.ncbi.nlm.nih.gov
- Daptomycin | Journal of Antimicrobial Chemotherapy - academic.oup.com
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