What is the primary action of Class II mGluRs on calcium influx?
Understand the Problem
The question is asking about the effects of Class II metabotropic glutamate receptors (mGluRs) on calcium influx, specifically identifying the primary action among multiple choices provided. This involves understanding the physiological role and mechanism of mGluRs in neurotransmission.
Answer
Class II mGluRs inhibit calcium influx by modulating calcium channels.
The primary action of Class II metabotropic glutamate receptors (mGluRs) involves inhibiting calcium influx by modulating calcium channels and synaptic transmission.
Answer for screen readers
The primary action of Class II metabotropic glutamate receptors (mGluRs) involves inhibiting calcium influx by modulating calcium channels and synaptic transmission.
More Information
Class II mGluRs are generally associated with the inhibition of synaptic transmission and are involved in neuroprotective processes.
Tips
A common mistake is confusing the function of different mGluR classes, as Class I mGluRs activate intracellular calcium release, unlike Class II which inhibits.
Sources
- Metabotropic Glutamate Receptor Activation Modulates Kainate and ... - jneurosci.org
- The modulation of calcium currents by the activation of mGluRs - link.springer.com
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