What is the function of the Fc region of an antibody?
Understand the Problem
The question is asking about the role of the Fc region of an antibody. The Fc region interacts with various immune cells and proteins to mediate different immune responses. Answering this question requires knowledge of antibody structure and function in immunology.
Answer
The Fc region of an antibody activates the immune system by binding to Fc receptors and complement proteins.
The Fc region of an antibody primarily mediates interaction with the immune system. It binds to Fc receptors on immune cells and complement proteins to activate effector functions like antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).
Answer for screen readers
The Fc region of an antibody primarily mediates interaction with the immune system. It binds to Fc receptors on immune cells and complement proteins to activate effector functions like antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).
More Information
The Fc region's ability to interact with various immune components allows antibodies to bridge the humoral and cellular arms of the immune system, directing a targeted immune response against specific antigens.
Tips
A common mistake is to confuse the functions of the Fab region (antigen-binding) with the Fc region (immune system interaction).
Sources
- Fragment Crystallizable Region - an overview | ScienceDirect Topics - sciencedirect.com
- Antibodies 101: Fc Effector Functions - Addgene Blog - blog.addgene.org
- Fragment Crystallizable Region - an overview | ScienceDirect Topics - sciencedirect.com
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