What is the clinical significance of measuring the levels of lactate dehydrogenase (LDH) isoenzymes in diagnosing tissue damage?
Understand the Problem
The question asks about the clinical relevance of measuring lactate dehydrogenase (LDH) isoenzymes to diagnose tissue damage. It presents four options concerning the tissue specificity and diagnostic utility of LDH isoenzymes.
Answer
LDH isoenzyme measurements help identify the type, location, and severity of tissue damage, aiding in diagnosing and monitoring diseases.
Measuring lactate dehydrogenase (LDH) isoenzymes helps in identifying the type of tissue damaged, its location in the body, and the extent of the damage. Elevated levels of specific LDH isoenzymes can indicate damage to particular organs or tissues, aiding in diagnosis and monitoring of various diseases.
Answer for screen readers
Measuring lactate dehydrogenase (LDH) isoenzymes helps in identifying the type of tissue damaged, its location in the body, and the extent of the damage. Elevated levels of specific LDH isoenzymes can indicate damage to particular organs or tissues, aiding in diagnosis and monitoring of various diseases.
More Information
There are five types of LDH isoenzymes, each associated with different tissues. For example, LDH-1 is found primarily in the heart, while LDH-5 is found in the liver and skeletal muscle.
Tips
A common mistake is to assume that a high total LDH level automatically pinpoints the exact location of tissue damage. An isoenzyme test is needed to determine the source of tissue damage.
Sources
- Lactate Dehydrogenase (LDH) Isoenzymes Test - MedlinePlus - medlineplus.gov
- LDH (Lactate Dehydrogenase) Test: What It Is & Results - my.clevelandclinic.org
- Clinical and Diagnostic Significance of Lactate Dehydrogenase and ... - pmc.ncbi.nlm.nih.gov
AI-generated content may contain errors. Please verify critical information
